- Antimicrobial agents and applications
- Foot and Ankle Surgery
- Diabetic Foot Ulcer Assessment and Management
- Retinal Imaging and Analysis
- Monetary Policy and Economic Impact
- Biopolymer Synthesis and Applications
- Retinal Diseases and Treatments
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Infrared Thermography in Medicine
- Orthopedic Surgery and Rehabilitation
- Occupational and environmental lung diseases
- Lower Extremity Biomechanics and Pathologies
- Skin Protection and Aging
- Speech and Audio Processing
- Ear Surgery and Otitis Media
- Market Dynamics and Volatility
- Occupational exposure and asthma
- Corrosion Behavior and Inhibition
- Statistical Distribution Estimation and Applications
- Air Quality and Health Impacts
- Financial Risk and Volatility Modeling
- Diabetes Treatment and Management
- Cutaneous Melanoma Detection and Management
- Statistical Methods and Inference
- Digital Imaging for Blood Diseases
Korea University
2003-2025
Ansan University
2020-2025
Kyungpook National University
2024
Korea University Medical Center
2010-2024
Baylor University Medical Center
2024
Gangnam Severance Hospital
2024
Yonsei University
2024
University of British Columbia
2023
BC Cancer Agency
2023
Severance Hospital
2020
We described a challenge named "DRAC - Diabetic Retinopathy Analysis Challenge" in conjunction with the 25th International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI 2022). Within this challenge, we provided DRAC datset, an ultra-wide optical coherence tomography angiography (UW-OCTA) dataset (1,103 images), addressing three primary clinical tasks: diabetic retinopathy (DR) lesion segmentation, image quality assessment, DR grading. The scientific...
Abstract Polyhexamethylene guanidine phosphate (PHMG-p) is a major component in humidifier disinfectants, which cause life-threatening lung injuries. However, to our knowledge, no published studies have investigated associations between PHMG-p dose and damage severity with long-term follow-up. Therefore, we evaluated longitudinal dose-dependent changes injuries using repeated chest computed tomography (CT). Rats were exposed low (0.2 mg/kg, n = 10), intermediate (1.0 high (5.0 10) doses of...
Asymptotic normality of the posterior is a well understood result for dynamic as nondynamic models based on sets abstract conditions whose actual applicability hardly known especially case nonstationarity. In this paper we provide set by which can relatively easily prove asymptotic under quite general situations possible This reinforces and generalizes point Sims Uhlig (1991) that inference likelihood principle, explained Berger Wolpert (1988), will be unchanged regardless whether data are...
Recent investigations have revealed the crucial role of von Willebrand factor (vWF) in platelet thrombus formation under flow conditions. The plasma concentrations vWF were measured together with various hemodynamic and hemostatic parameters 51 cases acute myocardial infarction. In 10 randomly selected cases, distribution multimers serially determined after reperfusion therapy by percutaneous transluminal coronary angioplasty (PTCA). concentration at onset infarction was significantly higher...
Abstract Background Lung injury elicited by respiratory exposure to humidifier disinfectants (HDs) is known as HD-associated lung (HDLI). Current elucidation of the molecular mechanisms related HDLI mostly restricted fibrotic and inflammatory diseases. In our previous report, we found that tumors were caused intratracheal instillation polyhexamethylene guanidine phosphate (PHMG-p) in a rat model. However, cancer-related genetic changes concomitant with development these have not yet been...
Background: We investigated whether fasting glucose (FG) variability could predict the risk of dementia.Methods: This cohort study analyzed data from Koreans with diabetes after at least three health examinations by Korean National Health Insurance Corporation between 2005 and 2010, which included one examination 2009 2010. A total 769,554 individuals were included, excluding those aged <40 years dementia. FG was measured using independent mean (FG-VIM). The incidence dementia defined...
Air pollution is a risk factor that increases cardiovascular morbidity and mortality. In this study, we investigated the cardiotoxicity of particulate matter (PM) exposure using zebrafish embryo model. We found PM induced cardiotoxicity, such as arrhythmia, during cardiac development. caused by altering expression levels development (T-box transcription 20, natriuretic peptide A, GATA-binding protein 4)- ion-channel (scn5lab, kcnq1, kcnh2a/b, kcnh6a/b)-related genes. conclusion, study showed...
Weight-bearing computed tomography (WBCT) enables acquisition of three dimensional bony structure images in a physiological weight-bearing position, which is fundamental under-standing the pathologic lesions and deformities ankle joint. Over past decade, re-searchers focused on validating developing WBCT measurements, has significantly enhanced our knowledge common foot disease. Consequently, understanding application clinical practice becoming more important to produce improved out-comes...
Submission Type: Ankle Arthritis Research Level 3 - Retrospective cohort study, Case-control Meta-analysis of studies Introduction/Purpose: Improving range motion (ROM) is one the most challenging objectives in total ankle replacement (TAR). While preserving advantages TAR comparison to fusion, factors that interfere with ROM are not well established literature. Movement joint predominantly occurs sagittal plane, yet no study has analyzed how alignment interferes ROM. Our aims evaluate...
Abstract Our aim was to correlate chest CT and pathologic findings of polyhexamethylene guanidine phosphate (PHMG)-induced lung injuries in a rat model, determine whether PHMG exposure causes tumors, explore genetic alterations according under the guidance CT. A solution intratracheally administrated 40 male rats. Chest carried out all rats both lungs were collected for histopathologic evaluation. At 4- 8-weeks post-instillation, one lobe right from 3 subjected RNA sequencing. least abnormal...
A diabetic wound presents a severe risk of infections and other complications because its slow healing. Evaluating the pathophysiology during healing is imperative for care, necessitating proper model assay monitoring. The adult zebrafish rapid robust studying human cutaneous fecundity high similarities to repair. OCTA as an can provide three-dimensional (3D) imaging tissue structure vasculature in epidermis, enabling monitoring pathophysiologic alterations skin wound. We present...
As the number of elderly drivers rapidly increases worldwide, interest in dangers driving is growing as accidents rise. The purpose this study was to conduct a statistical analysis risk factors drivers. In analysis, data from government organization’s open were used for secondary processing 10,097 people. Of 9990 respondents, 2168 current drivers, 1552 past but not presently, and 6270 did have driver’s license; participants divided into groups accordingly. who had better subjective health...
This study aimed to evaluate the effects of COVID-19 pandemic on obesity, metabolic parameters, and clinical values in South Korean population. Data from seventh eighth National Health Nutrition Examination Surveys were analyzed, comprising 3560 participants 2018 (pre-COVID-19) 3309 2021 (post-COVID-19). The focused adults aged 19 years older who overweight (BMI ≥ 25 kg/m2). results showed a significant increase waist circumference (approximately 2 cm), BMI 0.11 kg/m2), systolic blood...
Weight-bearing computed tomography (WBCT) enables acquisition of three dimensional bony structure images in a physiological weight-bearing position, which is fundamental under-standing the pathologic lesions and deformities ankle joint. Over past decade, re-searchers focused on validating developing WBCT measurements, has significantly enhanced our knowledge common foot disease. Consequently, understanding application clinical practice becoming more important to produce improved out-comes...
There have been no studies on the effects of polyhexamethylene guanidine phosphate (PHMG) after a long period exposure in rodent model. We aimed to evaluate long-term lung damage PHMG using conventional chest computed tomography (CT) and histopathologic analysis rat A solution was intratracheally administrated 24 male rats. At 8, 26, 52 weeks instillation, CT performed all rats both lungs were extracted for evaluation. four carcinomas had developed three eight (37.5%). Bronchiolo-alveolar...
This study aimed to develop a diabetes prediction model. The model performance was compared with logistic regression, and the decision tree Chi-square automatic interaction detection (CHAID) used predict diabetes. In total, 3233 patients were included in analysis. Of these, 589 2644 without after analyzing sample from Korean Genome Epidemiology Study (KoGES)-8 data. this study, Diabetes Mellitus (DM) diagnosis regression through machine learning (ML) using CHAID classification tree. We...
Otitis media (OM) is a common disease in childhood that may have aftereffects such as hearing loss. Therefore, early diagnosis and proper treatment are important. However, the diagnostic accuracies of otolaryngology pediatrics low, at 73% 50%, respectively. clinical work supports diseases, computer-aided (CAD) systems, can be helpful. CAD systems for diagnosing ear diseases require an automatic tympanic membrane (TM) segmentation model to assist diagnosis. This because it difficult detect TM...