A5003810567- Cardiac Arrest and Resuscitation
- Acute Myocardial Infarction Research
- Blood Pressure and Hypertension Studies
- Cardiac Imaging and Diagnostics
- Cardiac Health and Mental Health
- Sex and Gender in Healthcare
- Heart Failure Treatment and Management
- Cardiac Valve Diseases and Treatments
- Cardiac pacing and defibrillation studies
- Venous Thromboembolism Diagnosis and Management
- Trauma and Emergency Care Studies
- Health Systems, Economic Evaluations, Quality of Life
- Palliative Care and End-of-Life Issues
- Healthcare Policy and Management
- Acute Ischemic Stroke Management
- Cardiac Arrhythmias and Treatments
- Health disparities and outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Mechanical Circulatory Support Devices
- Racial and Ethnic Identity Research
- Emergency and Acute Care Studies
- Cardiovascular Function and Risk Factors
- Diversity and Career in Medicine
- Pharmaceutical Practices and Patient Outcomes
- Cardiac electrophysiology and arrhythmias
Kaiser Permanente
2009-2025
University of Colorado Denver
2016-2025
Colorado Permanente Medical Group
2024-2025
Outcomes Research Consortium
2012-2024
University of Colorado Anschutz Medical Campus
2013-2024
Children's Hospital of Orange County
2024
Ultragenyx Pharmaceutical (United States)
2023
Collins College
2020-2021
American Society of Echocardiography
2019
American Heart Association
2011-2019
Background— Despite a recent American Heart Association (AHA) consensus statement emphasizing the importance of resistant hypertension, incidence and prognosis this condition are largely unknown. Methods Results— This retrospective cohort study in 2 integrated health plans included patients with incident hypertension whom treatment was begun between 2002 2006. Patients were followed up for development based on AHA criteria uncontrolled blood pressure despite use ≥3 antihypertensive...
Resistant hypertension (RH) is defined as above-goal elevated blood pressure (BP) in a patient despite the concurrent use of 3 antihypertensive drug classes, commonly including long-acting calcium channel blocker, blocker renin-angiotensin system (angiotensin-converting enzyme inhibitor or angiotensin receptor blocker), and diuretic. The drugs should be administered at maximum maximally tolerated daily doses. RH also includes patients whose BP achieves target values on ≥4 medications....
Background— Women are at higher risk than men for adverse events with certain invasive cardiac procedures. Our objective was to compare rates of in-hospital in and women receiving implantable cardioverter- defibrillator (ICD) therapy community practice. Methods Results— Using the National Cardiovascular Data Registry ICD Registry, we identified patients undergoing first-time implantation between January 2006 December 2007. Outcomes included after implantation. Multivariable analysis assessed...
Physicians' gender bias may contribute to disparities in cardiovascular testing. We used the Implicit Association Test examine association of implicit biases with decisions use tests.In 2014, cardiologists completed Tests and a clinical vignette patient randomly assigned. The measured for characteristics strength risk taking. represented an intermediate likelihood coronary artery disease regardless gender: chest pain (part 1) followed by abnormal exercise treadmill test 2). Cardiologists...
Background Despite higher thromboembolism risk, women with atrial fibrillation have lower oral anticoagulation ( OAC ) use compared to men. The influence of the CHA 2 DS ‐ VAS c score or introduction non–vitamin K s on this relationship is not known. Methods and Results Using PINNACLE National Cardiovascular Data Registry from 2008 2014, we association sex (warfarin s) overall by examined temporal trends in sex. Multivariable regression models assessed between those scores ≥2. Temporal...
Background: Women who suffer an out-of-hospital cardiac arrest receive bystander cardiopulmonary resuscitation (CPR) less often than men. Understanding public perceptions of why this occurs is a necessary first step toward equitable application potentially life-saving intervention. Methods: We conducted national survey members the using Mechanical Turk, Amazon’s crowdsourcing platform, to determine reasons women might CPR Eligible participants were adults (≥18 years) located in United...
Despite women having fewer traditional risk factors (eg, hypertension, diabetes), strokes are more common in than men aged ≤45 years. This study examined the contributions of and nontraditional migraine, thrombophilia) development among young adults.
To provide an integrated assessment of changes in systolic and diastolic function diabetic rats, we measured conscious hemodynamics performed ex vivo analysis left ventricular passive-elastic properties. Rats given streptozotocin (STZ) 65 mg/kg i.v. (n = 14) were compared with untreated age-matched controls 15) rats treated insulin after administration STZ 11). After 7 d, exhibited decreases heart rate peak developed (LV) pressure during aortic occlusion. 26 d diabetes there significant...
Despite gender-neutral guidelines, prior studies suggest that women have lower rates of hypertension control and these differences may vary with age. Accordingly, we compared between men as a function age.Within three integrated healthcare systems in the Cardiovascular Research Network, studied all patients seen from 2001 to 2007 incident hypertension. Within 1 year cohort entry, patient's was categorized controlled based upon achieving guideline-recommended blood pressure levels, recognized...
Patients with resistant hypertension are at risk for poor outcomes. Medication adherence and intensification improve blood pressure (BP) control; however, little is known about these processes or their association outcomes in hypertension. This retrospective study included patients from 2002 to 2006 incident 2 health systems who developed uncontrolled BP despite ≥3 antihypertensive medications. Patterns of treatment, medication (percentage days covered), treatment (increase class dose) were...
Background The proportion of racial/ethnic minorities receiving ventricular assist devices (VADs) has previously been less than expected. It is unclear if trends have changed since the broadening access to insurance in 2014 and rapid adoption VAD technology. Methods Results Using Interagency Registry Mechanically Assisted Circulatory Support, we analyzed time by race/ethnicity for 10 795 patients (white, 67.4%; African-American, 24.8%; Hispanic, 6.3%; Asian, 1.5%) who had a implanted between...
Cardiovascular risk factors, which are overall more prevalent in men, considered the major factors for strokes among young adults. However, recent European data found incidence of to be higher women. Using a large US claims sample, we examined sex differences index stroke rate We performed retrospective cohort study enrollees 10% random sample PharMetrics, nationally representative database insured Americans from 2001 2014. Outcomes were ischemic events, based on inpatient admissions using...
Background— Geriatric conditions may influence outcomes among patients receiving implantable cardioverter-defibrillators (ICDs). We sought to determine the prevalence of frailty and dementia older adults primary prevention ICDs impact multimorbidity on mortality within 1 year ICD implantation. Methods Results— The cohort included 83 792 Medicare from National Cardiovascular Data Registry who underwent first implantation between 2006 2009. These data were merged with analytic files frailty,...