Zahoor A. Shah

ORCID: 0000-0001-8977-1618
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About
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Research Areas
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Neurological Disease Mechanisms and Treatments
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Ginkgo biloba and Cashew Applications
  • Acute Ischemic Stroke Management
  • Alzheimer's disease research and treatments
  • Neurotransmitter Receptor Influence on Behavior
  • Genomics, phytochemicals, and oxidative stress
  • Barrier Structure and Function Studies
  • S100 Proteins and Annexins
  • Memory and Neural Mechanisms
  • Inflammatory mediators and NSAID effects
  • Autophagy in Disease and Therapy
  • Stress Responses and Cortisol
  • Gut microbiota and health
  • Neurological Disorders and Treatments
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Animal Nutrition and Physiology
  • Obstructive Sleep Apnea Research
  • Reproductive Physiology in Livestock
  • Neuroscience of respiration and sleep
  • Zebrafish Biomedical Research Applications
  • Phytochemicals and Medicinal Plants
  • Forensic Entomology and Diptera Studies
  • Advancements in Transdermal Drug Delivery

University of Toledo
2013-2025

COMSATS University Islamabad
2021

Islamic Azad University, Shahrood
2020

North China Electric Power University
2020

Khwaja Fareed University of Engineering and Information Technology
2019

Sher-i-Kashmir Institute of Medical Sciences
2013

Johns Hopkins University
2006-2011

Johns Hopkins Medicine
2006-2011

Kosair Children's Hospital
2008

University of Louisville
2006-2008

The research experiment was carried out to investigate the cultivation of Oyster mushroom on different substrates. Mushroom is a profitable agribusiness. Incorporation non conventional crops in existing agricultural system can improve economic status farmer. Mushrooms are source protein, vitamins and minerals anticancerous, anticholesteral, antitumorous. Sawdust produced highest yield, biological efficiency number fruiting bodies, recommended as best substrate for cultivation.

10.3923/pjn.2004.158.160 article EN Pakistan Journal of Nutrition 2004-04-15

Epidemiologic studies have shown that foods rich in polyphenols, such as flavanols, can lower the risk of ischemic heart disease; however, mechanism protection has not been clearly established. In this study, we investigated whether epicatechin (EC), a flavanol cocoa and tea, is protective against brain damage mice. Wild-type mice pretreated orally with 5, 15, or 30 mg/kg EC before middle cerebral artery occlusion (MCAO) had significantly smaller infarcts decreased neurologic deficit scores...

10.1038/jcbfm.2010.53 article EN Journal of Cerebral Blood Flow & Metabolism 2010-05-05

An experiment was designed to study the effect of foliar application micronutrients on yield, quality and leaf composition sweet orange, Blood red variety at Shabazgari, Mardan. The laid out in a randomized complete block design 2) factorial arrangement. Zinc, manganese boron were applied as spray rate 0.4, 0.2 0.04 kg ha(-1), respectively presence 1.56 N ha(-1) urea 0.4 surfactance (as wetting agent) 400 L water. maximum fruit yield obtained, when Zn Mn sprayed along with minimum % peel...

10.3923/pjbs.2007.1823.1828 article EN Pakistan Journal of Biological Sciences 2007-05-15

Erectile dysfunction (ED) is frequent in obstructive sleep apnea syndrome (OSAS). Chronic intermittent hypoxia (CIH), one of the hallmarks OSAS, could mediate ED.To determine whether during affects erectile mice.Three groups C57BL/6 mice were exposed to CIH for 5 or 24 weeks. Sexual function was evaluated by vivo telemetry corpus spongiosum pressure. Spontaneous erections, sexual activity mating, and noncontact tests assessed after weeks treatment with tadalafil. Plasma testosterone measured...

10.1164/rccm.200801-190oc article EN American Journal of Respiratory and Critical Care Medicine 2008-06-06

Ebselen (EBS) is an organo-selenium-containing compound that has anti-inflammatory, antitumor, and antibacterial properties. EBS being explored as a possible treatment for reperfusion injury stroke under clinical trials mimetic of lithium the bipolar disorder [Mota et al. Synapse 2020, 74 (7), 1−6] noise-induced hearing loss result these actives [Martini J. Psychiatr. Res. 2019, 109, 107−117. Slusarczyk Neural Regener. 17 1255–1261. Thangamani PLoS One 2015, 10 e0133877. Kil Lancet 2017, 390...

10.1021/acschemneuro.0c00328 article EN ACS Chemical Neuroscience 2020-08-25

Microglial activation and failure of the antioxidant defense mechanisms are major hallmarks in different brain injuries, particularly traumatic injury (TBI). Cofilin is a cytoskeleton-associated protein involved actin binding severing. In our previous studies, we identified putative role cofilin mediating microglial apoptosis ischemic hemorrhagic conditions. Others have highlighted involvement ROS production resultant neuronal death; however, more studies needed to delineate oxidative stress...

10.3390/biology12040630 article EN cc-by Biology 2023-04-21

Abstract: Stroke, or ischaemic brain damage, is of great geriatric importance being the third most common cause death after cancer and heart diseases in developed countries. Despite such high frequency, its management has received inadequate attention. Many studies have shown role free radicals pathogenesis damage. Search for safe effective antioxidant radial scavenger agents, therefore, appear to be a promising approach stroke therapy. Gold, widely used modern medicine treatment rheumatoid...

10.1034/j.1600-0773.2002.900505.x article EN Pharmacology & Toxicology 2002-05-01

Tyrosine hydroxylase, a hypoxia-regulated gene, may be involved in tissue adaptation to hypoxia. Intermittent hypoxia, characteristic feature of sleep apnea, leads significant memory deficits, as well cortex and hippocampal apoptosis that are absent after sustained To examine the hypothesis intermittent hypoxia induce different catecholaminergic responses, changes tyrosine hydroxylase mRNA, protein expression, activity were compared various brain regions male rats exposed for 6 h, 1 day, 3...

10.1152/japplphysiol.00880.2004 article EN Journal of Applied Physiology 2005-04-08
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