Hugh Sorby

ORCID: 0000-0001-8991-4703
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About
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Research Areas
  • Artificial Intelligence in Healthcare and Education
  • Gene Regulatory Network Analysis
  • Research Data Management Practices
  • Neonatal skin health care
  • Health, Environment, Cognitive Aging
  • Cystic Fibrosis Research Advances
  • Scientific Computing and Data Management
  • RNA Interference and Gene Delivery
  • Glioma Diagnosis and Treatment
  • Bioinformatics and Genomic Networks
  • Slime Mold and Myxomycetes Research
  • Musculoskeletal pain and rehabilitation
  • Cerebrospinal fluid and hydrocephalus
  • Data Analysis with R
  • Cardiovascular Function and Risk Factors
  • Meta-analysis and systematic reviews
  • Microbial Metabolic Engineering and Bioproduction
  • Neurological and metabolic disorders
  • Machine Learning in Healthcare

University of Auckland
2014-2024

Computational models have great potential to accelerate bioscience, bioengineering, and medicine. However, it remains challenging reproduce reuse simulations, in part, because the numerous formats methods for simulating various subsystems scales remain siloed by different software tools. For example, each tool must be executed through a distinct interface. To help investigators find use simulation tools, we developed BioSimulators (https://biosimulators.org), central registry of capabilities...

10.1093/nar/gkac331 article EN cc-by Nucleic Acids Research 2022-04-21

Abstract We present here CellML 2.0, an XML-based language for describing and exchanging mathematical models of physiological systems. MathML embedded in documents is used to define the underlying mathematics models. Models consist a network reusable components, each with variables equations giving relationships between those variables. may import other create systems increasing complexity. 2.0 defined by normative specification presented here, prescribing syntax rules which it should be...

10.1515/jib-2020-0021 article EN cc-by Berichte aus der medizinischen Informatik und Bioinformatik/Journal of integrative bioinformatics 2020-06-01

Abstract We present here CellML 2.0.1, an XML-based language for describing and exchanging mathematical models of physiological systems. MathML embedded in documents is used to define the underlying mathematics models. Models consist a network reusable components, each with variables equations giving relationships between those variables. may import other create systems increasing complexity. 2.0.1 defined by normative specification presented here, prescribing syntax rules which it should be...

10.1515/jib-2023-0003 article EN cc-by Berichte aus der medizinischen Informatik und Bioinformatik/Journal of integrative bioinformatics 2023-03-01

The integrated maps viewer of the SPARC Portal ( https://sparc.science ) provides interactive, modular, and continually-updated visualizations nerve-organ anatomy function. data knowledge is registered onto two-dimensional flatmaps, three-dimensional anatomical organ whole-body scaffolds. Flatmaps are zoomable built from a range sources portray nerve given species, scaffold geometric models able to represent spatial distribution connectivity knowledge, observed data, computational models....

10.1152/physiol.2024.39.s1.2483 article EN Physiology 2024-05-01

In this protocol, we will demonstrate how to prepare a generic organ scaffold for publication as SPARC dataset using the Scaffold mapping tools. This protocol ensure that is made available and reusable community in reproducible manner.

10.17504/protocols.io.6qpvr8q72lmk/v1 preprint EN 2024-08-16

In this protocol, we will demonstrate how to prepare a generic organ scaffold for publication as SPARC dataset using the Scaffold mapping tools. This protocol ensure that is made available and reusable community in reproducible manner.

10.17504/protocols.io.6qpvr8q72lmk/v4 preprint EN 2024-08-16
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