A5042376448- Retinal Diseases and Treatments
- Corneal surgery and disorders
- Glaucoma and retinal disorders
- Retinal Imaging and Analysis
- Corneal Surgery and Treatments
- Retinal and Optic Conditions
- Ocular Diseases and Behçet’s Syndrome
- Ocular Surface and Contact Lens
- Retinal and Macular Surgery
- Intraocular Surgery and Lenses
- Systemic Lupus Erythematosus Research
- Allergic Rhinitis and Sensitization
- Ophthalmology and Visual Impairment Studies
- Drug-Induced Ocular Toxicity
- Retinal Development and Disorders
- Infection Control and Ventilation
- Ocular Infections and Treatments
- Salivary Gland Disorders and Functions
- Ocular Oncology and Treatments
- Skin Protection and Aging
- Dermatologic Treatments and Research
- Spaceflight effects on biology
- Retinopathy of Prematurity Studies
- Urban Green Space and Health
- Aortic aneurysm repair treatments
Aintree University Hospitals NHS Foundation Trust
2024-2025
University of Liverpool
2023-2025
University of Brescia
2023-2025
Royal Liverpool University Hospital
2023-2025
Royal Liverpool and Broadgreen University Hospital NHS Trust
2025
Luigi Sacco Hospital
2020-2024
University of Milan
2020-2024
University of Naples Federico II
2024
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
2023-2024
Veneto Eye Bank Foundation
2024
To report the incidence and risk factors for fibrosis at 10 years in a large cohort of persons with neovascular age-related macular degeneration (nAMD).Retrospective, multicenter, study.We included 225 naive nAMD eyes that underwent intravitreal anti-vascular endothelial growth factor treatment over follow-up two Italian referral centers. Demographic clinical data were reviewed baseline on an annual basis. Onset was defined by clinically assessing photographs, fundus descriptions, or...
Purpose:To investigate the reduction of ocular surface bacterial load induced by two commercially available ophthalmic antiseptic formulations, povidone-iodine (PVI) 0.6% and chlorexidine (CLX) 0.02%, before surgery.Design:Randomized controlled trial.MethodsSeventy adult patients, undergoing intraocular surgery (phacoemulsification), were randomized to receive in index eye PVI (group A) QID for 3 days or CLX B)" surgery. The untreated was used as control. A conjunctival swab taken both eyes...
Airaldi, Matteo MD; Passaro, Maria Laura Ventura, Mariacarmela Vaccaro, Sabrina Ancona, Chiara Semeraro, Francesco Costagliola, Ciro Romano, Vito MD Author Information
To report the incidence and risk factors for fibrosis at 10 years in a large cohort of persons with neovascular age-related macular degeneration (nAMD).Retrospective, multicenter, study.We included 225 naive nAMD eyes that underwent intravitreal anti−vascular endothelial growth factor treatment over follow-up two Italian referral centers. Demographic clinical data were reviewed baseline on an annual basis. Onset was defined by clinically assessing photographs, fundus descriptions, or...
Purpose: To evaluate a novel deep learning algorithm to distinguish between eyes that may or not have graft detachment based on pre–Descemet membrane endothelial keratoplasty (DMEK) anterior segment optical coherence tomography (AS-OCT) images. Methods: Retrospective cohort study. A multiple-instance artificial intelligence (MIL-AI) model using ResNet-101 backbone was designed. AS-OCT images were split into training and testing sets. The MIL-AI trained validated the set. Model performance...
Purpose: To describe an early sterile keratolysis associated with a decellularized porcine corneal inlay implant for keratoconus. Methods: This is case report of 23-year-old man keratoconus who underwent lenticular intrastromal keratoplasty in his OD. Within 4 weeks, the patient presented anterior and partial extrusion, leading to surgical removal. Results: After removal, despite aggressive topical treatment including steroid drops, antibiotic ointment, bandage contact lenses, developed...
To report visual outcomes and rate of retinal pigment epithelium (RPE) atrophy progression in patients with extensive macular pseudodrusen-like appearance (EMAP).Retrospective, observational study.Patients EMAP symptom onset before 55 years age, at least 12 months follow-up using Spectralis blue-light fundus autofluorescence (BAF) OCT no other ocular or systemic conditions.Best-corrected acuity (BCVA), BAF, images were reviewed baseline each annual visit until the last available follow-up....
Purpose To evaluate the influence of immunomodulatory therapy (IMT) on visual and treatment outcomes inflammatory choroidal neovascularization (iCNV) in patients affected by Multifocal Choroiditis (MFC), to compare them treated with steroids as needed. Design Multicenter retrospective matched cohort study. Methods Patients MFC iCNV were divided a IMT group "steroids needed" according time between diagnosis beginning systemic treatment. Visual acuity, number anti-Vascular Endothelial Growth...
Purpose: To investigate the role of preoperative posterior stromal ripples (pre-PSR) on visual acuity recovery after Descemet membrane endothelial keratoplasty (DMEK). Methods: This is a comparative case series retrospectively analyzing patients who underwent DMEK. Electronic records and imaging DMEK were reviewed. The last first postoperative available anterior segment optical coherence tomography scans for each eye analyzed presence pre-PSR. difference in longitudinal trends was assessed...
To describe a novel surgical technique using trypan blue assistance for iris cyst excision. With viscoelastic in the anterior chamber, contents are aspirated with 27G needle. Trypan is then injected into residual cavity to stain its walls. Forceps and vitrectomy utilized ensure complete removal of wall safe margin surrounding tissue. The blue-assisted facilitates visualization, enabling precise removal. excision provides an effective approach stromal removal, minimizing recurrence risk...
Abstract Background The NHS has committed to achieving net-zero carbon emissions by 2045. Dry eye disease, a chronic condition affecting approximately 29.5% of the global population, poses significant challenge due its environmentally harmful care pathway, which also exacerbates condition. This research article presents multi-centre cross-sectional survey patients with severe dry disease examine pollution and associated pathway. aim is identify target areas where innovation can aid in...
Purpose: To report the incidence, features, and clinical outcomes of macular neovascularization (MNV) in a large Italian cohort patients with extensive atrophy pseudodrusen-like appearance (EMAP). Methods: Retrospective, longitudinal study including 79 EMAP (158 eyes) ≥6 months follow-up at three retina clinics. Medical records imaging were reviewed for demographic data, age, best-corrected visual acuity (BCVA), MNV retinal pigment epithelium (RPE) size, measured by short-wavelength...
Aim: To interpret the likely clinical susceptibility of isolates from microbial keratitis we performed a meta-analysis published data that measured concentrations of, topically applied, antimicrobials in cornea or aqueous humour. We then correlated these values with vitro minimum inhibitory concentration (MIC). Methods and Analysis: searched PubMed to identify studies reporting and/or corneal 53 applied ocular antimicrobials, spanning following classes: beta-lactams, glycopeptides,...
The aim of this study was to compare complication rates Descemet membrane endothelial keratoplasty (DMEK) performed by directly supervised and nondirectly corneal fellows.This a retrospective, comparative case series DMEK surgeries novice surgeons (less than 15 cases) with or without direct expert supervision. Patients who underwent surgery for Fuchs dystrophy pseudophakic bullous keratopathy minimum follow-up 12 weeks were included. Data on patients' demographics, surgical details, surgeon...
Abstract Background To compare the change in lesion area over 4 years of follow-up eyes with neovascular age-related macular degeneration (nAMD) treated anti-vascular endothelial growth factor (VEGF) agents using either a proactive or reactive regimen routine clinical practice. Methods This was multicentre, retrospective comparative study. Totally, 202 treatment-naïve nAMD (183 patients) received anti-VEGF therapy according to ( n = 105) 97) regimen. Eyes were included if they had injections...
To evaluate the Descemet membrane endothelial keratoplasty (DMEK) preparation performance of trainee surgeons in an ex vivo human donor cornea DMEK wet lab simulation setting.
Purpose: To compare the performance of 3 commercially available tomographers (the Pentacam Scheimpflug camera, swept-source optical coherence tomography Casia, and blue light slit-scanning tomographer Precisio) in identification patterns associated with Fuchs endothelial corneal dystrophy (FECD) decompensation. Methods: This was a clinic-based cross-sectional imaging study. Pachymetry maps posterior surface elevation were acquired devices from 61 eyes affected by FECD. The graded according...
Purpose: This study aims to investigate the potential in vivo relationship between macular pigment (MP) and retinal layers thickness healthy subjects dry, non-advanced age-related degeneration (AMD). Methods: An observational, cross-sectional was conducted. Healthy >40 years patients with early or intermediate AMD were recruited. Structural OCT optical volume (MPOV) collected for each subject. Retinal parameters calculated based on standard treatment diabetic retinopathy (ETDRS) map....
Purpose: The purpose of this study was to examine the direct impact on carbon emissions attributed use fluorinated gases in endothelial keratoplasty (EK) procedures using gas tamponade and evaluate respective footprint different delivery systems used EK procedures. Methods: In retrospective, single-center environmental study, all corneal between January 2021 2024 at Royal Liverpool University Hospital were reviewed included. CO 2 equivalent calculated based mass each used, following...
Purpose: The aim of this study was to assess the outcomes off-centered Descemet membrane endothelial keratoplasty (DMEK) grafts compared descemetorhexis. Methods: This is a retrospective case series DMEK procedures conducted between June 2022 and July 2023 with postoperative graft decentration, characterized by gap descemetorhexis edge. Results: Eight eyes 8 patients met inclusion criteria. average edge 911.2 μm (range 306–1468). resulting focal peripheral edema overlying resolved in all...