A5043017156- Frailty in Older Adults
- Health Systems, Economic Evaluations, Quality of Life
- Geriatric Care and Nursing Homes
- Insect and Pesticide Research
- Neurobiology and Insect Physiology Research
- Palliative Care and End-of-Life Issues
- Innovations in Medical Education
- Insect Resistance and Genetics
- Musculoskeletal Disorders and Rehabilitation
- Long-Term Effects of COVID-19
- Insect Pest Control Strategies
- Dementia and Cognitive Impairment Research
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Intensive Care Unit Cognitive Disorders
- Autoimmune and Inflammatory Disorders Research
- Insect-Plant Interactions and Control
- Pharmaceutical Practices and Patient Outcomes
- Entomopathogenic Microorganisms in Pest Control
- Nutrition and Health in Aging
- Nicotinic Acetylcholine Receptors Study
- Insect and Arachnid Ecology and Behavior
- Insect Utilization and Effects
- Plant Gene Expression Analysis
- Delphi Technique in Research
Dalhousie University
2007-2021
Harold Wood Hospital
2019
Nova Scotia Health Authority
2017
Capital District Health Authority
2016
University of Leeds
2012
University of the West of England
2006-2008
University of Bath
1998
Shell (Netherlands)
1973-1997
Shell (United Kingdom)
1974-1996
Wellcome Trust
1995
Older adults have been disproportionately affected by the COVID-19 pandemic, with many outbreaks occurring in Long Term Care Facilities (LTCFs). We discuss this vulnerability among LTCF residents using an ecological framework, on levels spanning from individual to families and caregivers, institutions, health services systems, communities, contextual government policies. Challenges abound for fully understanding burden of LTCF, including differences nomenclature, data collection cultural...
The authors were charged with making a series of evidence‐based recommendations that would provide concrete advice on all aspects the management mild to moderate stages dementia and Alzheimer's disease (AD). primarily targeted primary care physicians practicing in Canada. assigned topic area did not include either assessment patient suspected or prevention AD other dementias. An extensive examination available literature was conducted. Explicit criteria for grading strength level evidence...
The purpose of this manuscript was to evaluate the effectiveness Community Actions and Resources Empowering Seniors (CARES) model in measuring mitigating frailty among community-dwelling older adults.The CARES is based on a goal-oriented multidisciplinary primary care plan which combines comprehensive geriatric assessment (CGA) with health coaching. A total 51 adults (82 ± 7 years; 33 females) participated pilot phase initiative. Frailty measured using Clinical Scale (CFS) Index (FI-CGA) at...
<h3>Introduction:</h3> Care by Design™ (CBD) (Canada), a model of coordinated team-based primary care, was implemented in long-term care facilities (LTCFs) Halifax, Nova Scotia, Canada, to improve access and continuity reduce high rates transfers emergency departments (EDs). <h3>Methods:</h3> This an observational time series before after the implementation CBD (Canada). Participants are LTCF residents with 911 Emergency Health Services calls from 10 LTCFs, representing 1424 beds. Data were...
Abstract Manduca sexta is a nicotine‐insensitive insect, the larval form of which feeds on tobacco. It has been postulated that its nicotine insensitivity may reflect presence modified nicotinic acetylcholine receptor whose α subunits lack amino acid residues necessary for binding nicotine: we have performed ligand assays and molecular cloning to examine this hypothesis. [ 125 I]α‐Bungarotoxin bound specifically both adult membranes, with K d values 7.6 6.5 n m B max 119 815 fmol/mg protein,...
Abstract The chitin precursor [ 14 C] N ‐acetylglucosamine injected into the haemolymph of Spodoptera littoralis ( Boisduval) larva was incorporated exponentially with time. When caterpillars were at commencement feeding on acylurea‐treated leaf discs, flufenoxuron, teflubenzuron and diflubenzuron found to be equally effective inhibitors synthesis, measured after 21 h. dose response curves by are not parallel, indicating that relative potency compounds will vary across range . simultaneously...
BackgroundMost older adults living in long-term care facilities (LTCF) are frail and have complex needs. Holistic understanding of residents’ health status is key to providing good care. Comprehensive Geriatric Assessment (CGA) a valid assessment method which aims embrace complexity. Here we aimed study CGA that has been modified for use (the LTC-CGA) investigate its acceptability usefulness stakeholders users.MethodsThis mixed methods study, conducted 10 LTCFs Halifax, Nova Scotia, reviewed...
Patient engagement in research priority-setting is intended to democratize and increase impact. The objectives of the Canadian Frailty Priority Setting Partnership (PSP) were engage people with lived or clinical experience frailty, produce a list priorities related care, support, treatment older adults living frailty.The PSP was supported by Network, coordinated researchers Toronto, Ontario followed methods James Lind Alliance, which included establishing Steering Group, inviting partner...
Abstract Objectives Polypharmacy is both common and harmful for frail residents of long-term care facilities (LTCF). We aimed to study rates polypharmacy potentially inappropriate medications (PIMs) before after the implementation a new model coordinated primary in LTCF, ‘Care by Design (CBD)’. Methods This was an observational before/after 10 LTCFs Halifax, NS, Canada. Chart reviews were conducted 529 LTCF whom medication use available. Both regularly scheduled PRN included but topical,...
Objectives. Rheumatological conditions are common, thus nurses (Ns) occupational therapists (OTs) and physiotherapists (PTs) require at least basic rheumatology knowledge upon qualifying. The aim of this study was to develop a core set teaching topics potential ways delivering them.
Objectives. Rheumatological conditions are common and all health professionals (HPs) therefore need sufficient knowledge skills to manage patients safely effectively. The aim of this study was examine current undergraduate education in rheumatology for HPs the UK. Methods. A questionnaire sent curriculum organizers clinical placement officers courses adult nursing, occupational therapy (OT) physiotherapy (PT) UK ascertain nature amount theory exposure provided. Results. Of 47 26 OT 30 PT...
Prior to the implementation of a new model care in long-term facilities Capital District Health Authority, Halifax, Nova Scotia, residents entering were responsible for finding their own family physician. As result, was provided by many physicians few leading coordination and continuity challenges. In 2009, Authority (CDHA) implemented called "Care Design" which includes: dedicated physician per floor, 24/7 on-call coverage, standardized geriatric assessment tool, an interdisciplinary team...
Abstract The mode of action a nitromethylene heterocycle (NMH) insecticide was studied by patch–clamp techniques using cockroach embryonic cultures as an experimental model. Under whole‐cell recordings, this compound elicited inward currents resembling those induced O‐acetylcholine (ACh). reversal potentials for both ACh and the NMH were similar, suggesting that carried same species ion. Pharmacological investigations NMH‐induced responses revealed insecticidal is exerted through agonistic...
Abstract Flufenoxuron (“Cascade”) is a novel acylurea with acaricidal and insecticidal properties. It acts in similar manner to diflubenzuron (DFB) by impairing chitin incorporation into insect cuticle . Chitin can be localised cytochemically using the lectin, wheat germ agglutinin (WGA), which binds specifically N ‐acetylglucosamine‐containing polymers. WGA adsorbed monodisperse colloidal gold (WGA‐gold) was used as an electron‐dense marker for localising of sixth‐instar Spodoptera...
The SARS-CoV-2 (Severe Acute Respiratory Syndrome coronavirus 2) has led to more than 165 million COVID-19 cases and >3.4 deaths worldwide. Epidemiological analysis revealed that the risk of developing severe increases with age. Despite a disproportionate number older individuals long-term care facilities being affected by COVID-19, very little is understood about immune responses development humoral immunity in extremely old person after infection. Here we conducted serological study...
After ingestion of various amounts either [3H]ecdysone or [3H]20-hydroxyecdysone (0.8 ng to 10 μg) by sixth instar larvae the Egyptian cotton leafworm Spodoptera littoralis, apolar metabolites are rapidly detected in gut and frass. Hydrolysis products with Helix hydrolases releases solely [3H]20-hydroxyecdysone, respectively. This, coupled formation chemical derivatives (acetonide acetate) which cochromatograph authentic reference compounds on hptlc hplc demonstrates that these consist...