A5050945427- Parkinson's Disease Mechanisms and Treatments
- Neurological disorders and treatments
- Botulinum Toxin and Related Neurological Disorders
- Cardiovascular Syncope and Autonomic Disorders
- Sleep and related disorders
- Circadian rhythm and melatonin
- Genetic Neurodegenerative Diseases
- Restless Legs Syndrome Research
- Autism Spectrum Disorder Research
- Heart Rate Variability and Autonomic Control
- Parkinson's Disease and Spinal Disorders
- Sleep and Wakefulness Research
- Blood Pressure and Hypertension Studies
- Attention Deficit Hyperactivity Disorder
- SARS-CoV-2 and COVID-19 Research
- Pain Mechanisms and Treatments
- Pharmacovigilance and Adverse Drug Reactions
- Olfactory and Sensory Function Studies
- Pharmacological Effects and Toxicity Studies
- Bipolar Disorder and Treatment
- Cholinesterase and Neurodegenerative Diseases
- Cardiovascular Health and Disease Prevention
- Mitochondrial Function and Pathology
- Dysphagia Assessment and Management
- Biochemical Analysis and Sensing Techniques
Pontificia Universidad Católica Argentina
2013-2025
Consejo Nacional de Investigaciones Científicas y Técnicas
2016-2025
University of Buenos Aires
2016-2025
Instituto Universitario de Ciencias de la Salud - Fundación Héctor A. Barceló
2024-2025
Universidad Abierta Interamericana
2020-2023
Assistance Publique – Hôpitaux de Paris
2022
Centro Científico Tecnológico - Tucumán
2021
Centro Científico Tecnológico - San Juan
2015-2021
Université de Toulouse
2010-2017
Inserm
2009-2017
Freezing of gait (FOG) is a common axial symptom Parkinson disease (PD).To determine the prevalence FOG in large group PD patients, assess its relationship with quality life and clinical pharmacological factors, explore changes from off to on conditions patients motor fluctuations.Cross-sectional survey 683 idiopathic PD. Scores for were missing 11 who not included analysis. Patients recruited referral centers general neurology clinics public or private institutions France.Patients...
Inadequate sleep and disordered breathing (SDB) can impair learning skills. Questionnaires used to evaluate sleepiness in adults are usually inadequate for adolescents. We conducted a study the performance of Spanish version Pediatric Daytime Sleepiness Scale (PDSS) assess impact SDB on academic performance. A cross-sectional survey students from 7 schools 4 cities Argentina. questionnaire with PDSS was used. Questions occurrence snoring witnessed apneas were answered by parents. Mathematics...
Background Elderly adults should avoid medications with anticholinergic effects since they may increase the risk of adverse events, including falls, delirium, and cognitive impairment. However, data on burden are limited in subpopulations, such as individuals Parkinson disease (PD). The objective this study was to determine whether associated outcomes a PD inpatient population. Methods Using Cerner Health Facts® database, we retrospectively examined medication use, diagnoses, hospital...
Objectives To describe the post-marketing safety profile of respiratory syncytial virus prefusion F (RSVpreF) vaccine among pregnant individuals. Design This study analysed adverse event (AE) reports submitted to U.S. Food and Drug Administration’s Vaccine Adverse Event Reporting System (VAERS) database following RSVpreF immunisation from 1 September 2023 23 February 2024. Setting VAERS, as a national spontaneous surveillance system, provides insights into in real-world setting. Participants...
Pathological gambling (PG) in Parkinson's disease (PD) is a frequent impulse control disorder associated mainly with dopamine replacement therapy. As impairments decision-making were described independently PG and PD, the objective of this study was to assess processes PD patients without PG.Seven 13 age, sex, education severity matched behavior enrolled study. All assessed comprehensive neuropsychiatric cognitive evaluation, including tasks used abilities under ambiguous or risky...
Introduction: Abnormal oro‐buccal functions including dysarthria, sialorrhea and dysphagia commonly affect patients with Parkinson’s disease (PD). Objectives: To estimate the prevalence of such symptoms at baseline in first 419 PD included COPARK cohort to analyze their correlations patients’ demographics, clinical characteristics, drugs consumption. Methods: Patients were assessed using Unified Rating Scale, Hospital Anxiety Depression PDQ‐39. Dysarthria, sialorrhea, defined as UPDRS items...
Background Impulse-control disorders (ICDs) occur in patients with Parkinson disease (PD), especially younger on dopamine therapies. Objective To assess the prevalence of ICD symptoms and its pharmacological correlations a sample French PD without (poststroke). Methods Outpatients (poststroke) were screened for compulsive behaviors related to hypersexuality, shopping, pathological gambling, or eating by means Questionnaire Impulse-Control Disorders—short version. Full medical history Unified...
Pediatric Daytime Sleepiness Scale (PDSS), we found that somnolence was independently and signifi cantly related to poor grades in language or math after adjusting for age, gender, body mass index (BMI), the presence of snoring apneas. 2 sleep deprived children may lead reduced attention, causing impaired learning academic failure. 10background: A multi-step causality pathway connecting short duration daytime sleepiness leading attention performance as fi nal result can be envisaged.However...
Pain is a common nonmotor symptom in patients with Parkinson disease (PD) but the correct diagnosis of respective cause remains difficult because suitable tools are lacking, so far. We developed framework to differentiate PD- from non-PD-related pain and classify PD-related into 3 groups based on validated mechanistic descriptors (nociceptive, neuropathic, or nociplastic), which encompass all previously described PD types. Severity syndromes was scored by ratings intensity, frequency,...
We assessed the clinimetric properties of ataxia rating scales and functional tests, made recommendations regarding their use.A systematic literature search was conducted to identify instruments used rate symptoms. The identified ability tests were reviewed ranked by panel as "recommended," "suggested," or "listed" for assessment patients with discrete cerebellar disorders, using previously established criteria.We 14 (9 5 tests). "Recommended" symptoms severity were: Friedreich's ataxia,...
passive immunotherapy is a therapeutic alternative for patients with COVID-19. Equine polyclonal antibodies (EpAbs) could represent source of scalable neutralizing against SARS-CoV-2.we conducted double-blind, randomized, placebo-controlled trial to assess efficacy and safety EpAbs (INM005) in hospitalized adult moderate severe COVID-19 pneumonia 19 hospitals Argentina. Primary endpoint was improvement at least two categories WHO ordinal clinical scale day 28 or hospital discharge...
In this study, we examined the relationship between screen time use, sleep characteristics, daytime somnolence, and academic performance in school-aged adolescents. We surveyed 1,257 12- to 18-year-old adolescents attending 52 schools urban or suburban areas of Argentina. recorded daily exposure various screen-based activities, including video- online-gaming, social media, TV streaming. Screen device type hour before bedtime, patterns during weekdays weekends, somnolence (Pediatric Daytime...