A5101522429- dental development and anomalies
- Sirtuins and Resveratrol in Medicine
- Signaling Pathways in Disease
- Image Processing Techniques and Applications
- Calcium signaling and nucleotide metabolism
- Cell Image Analysis Techniques
- Sleep and Wakefulness Research
- Drilling and Well Engineering
- Network Security and Intrusion Detection
- School Health and Nursing Education
- Osteoarthritis Treatment and Mechanisms
- Hydraulic Fracturing and Reservoir Analysis
- Endoplasmic Reticulum Stress and Disease
- Phagocytosis and Immune Regulation
- Advanced Numerical Analysis Techniques
- Vagus Nerve Stimulation Research
- Neuroscience and Neuropharmacology Research
- Oil and Gas Production Techniques
- Image Retrieval and Classification Techniques
- Aesthetic Perception and Analysis
- Cellular Mechanics and Interactions
- Art History and Market Analysis
- Opinion Dynamics and Social Influence
- Complex Network Analysis Techniques
- Metallic Glasses and Amorphous Alloys
King University
2023-2024
Peking University
2018-2024
Stomatology Hospital
2024
Research Institute of Petroleum Exploration and Development
2024
Washington University in St. Louis
2020-2021
University of Science and Technology Beijing
2016
Beijing Jiaotong University
2014
Zhejiang University of Science and Technology
2014
Rutgers Sexual and Reproductive Health and Rights
2013
Bacterial colony morphology is the first step of classifying bacterial species before sending them to subsequent identification process with devices, such as VITEK 2 automated system and mass spectrometry microbial system. It essential a pre-screening because it can greatly reduce scope possible will make more specific increase work efficiency in clinical bacteriology. But this needs adequate laboratory expertise morphology, which especially difficult for beginners handle properly. This...
Highlights•The neurotoxin 3-acetylpyridine is converted into a SARM1 allosteric activator•The binding site relatively promiscuous•SARM1 candidate mediator of environmental neurotoxicity•SARM1 agonists could be developed selective agents for neurolytic therapySummarySARM1 an inducible TIR-domain NAD+ hydrolase that mediates pathological axon degeneration. activated by increased ratio NMN to NAD+, which competes activating site. When binds, the TIR domain released from autoinhibition, its...
The NAD+ hydrolase SARM1 is the central executioner of pathological axon degeneration. allosterically activated by an increased NMN/NAD+ ratio resulting from depletion or accumulation its precursor, NMN, typically due to loss labile synthetase NMNAT2 following injury. Another hydrolase, PARP1, hyperactivated DNA damage, triggering Parthanatos cell death pathway. We demonstrate that multiple mechanistically-distinct DNA-damaging agents lead activation and degeneration PARP1 activation....
Abstract Aims Orthodontic treatment commonly results in orthodontically induced inflammatory root resorption (OIIRR). This condition arises from excessive orthodontic force, which triggerslocal responses and impedes cementoblasts' mineralization capacity. Low‐intensity pulsed ultrasound (LIPUS) shows potential reducing OIIRR. However, the precise mechanisms through LIPUS reduces OIIRR remain unclear. study aimed to explore effects of on force‐treated cementoblasts its impact Methods We...
Accurately identifying network traffics at the early stage is very important for application of traffic identification. Recent years, more and research works have tried to build effective machine learning models identify with few packets stage. However, a basic problem still unresolved, that how many are most in In this paper, we try resolve using experimental methods. We firstly extract packet size first 2-10 3 data sets. And then execute crossover identification experiments different...
In this paper, computer-based techniques for stylistic analysis of paintings are applied to the five panels 14th century Peruzzi Altarpiece by Giotto di Bondone. Features extracted combining a dual-tree complex wavelet transform with hidden Markov tree (HMT) model. Hierarchical clustering is used identify keywords in image patches, and keyword frequencies calculated sub-images that each contains many patches. A generative hierarchical Bayesian model learns patterns keywords; these then...
SUMMARY SARM1 is an inducible TIR-domain NAD + hydrolase that mediates pathological axon degeneration. activated by increased ratio of NMN to , which competes for binding allosteric activating site. When binds, the TIR domain released from autoinhibition, its activity. The discovery this site led us hypothesize other -related metabolites might also activate SARM1. Here we show nicotinamide analogue 3-acetylpyridine (3-AP), first identified as a neurotoxin in 1940s, converted 3-APMN activates...
The Ministry of Education and other four departments jointly issued the Notice on Construction high-level schools public Health, proposing that "it will take ten years to build a number health, form high-quality education development system adapt construction modern health system". At present, in various universities China is full swing. School Public Health CDC have played an important role constructing national human community. are strategic significance value CDC. review presents...
<title>Abstract</title> <bold>Introduction: </bold>The present study aimed to preliminarily compare the differences of condyle relocation range (CRR) between skeletal class II and III patients. <bold>Methods:</bold> Twenty twenty young adult patients underwent wide-field cone beam computed tomography (CBCT) scans maximum intercuspation position (MIP) most comfortable forward (MCFR). We superimposed CBCT images in two positions according bilateral zygomatic bone surface structure then...
The online social network has become an important information transmitting media. Finding the sources of topic on networks (OSNs), which helps us to know cause events, identify authenticity and target origin rumors, is very important. However, locating difficult because structure OSNs complex complete are hard observe. At same time, fact that diffusion process multiple-source, asynchronous uncertain, causes be more difficult. In this paper we aim solve problem in uncertainty networks. We...
Objectives: Orthodontic treatment often requires a long duration and leads to alveolar bone resorption. The effect of low-intensity pulsed ultrasound (LIPUS) on remodeling during orthodontic is still unclear. This study aimed investigate the impact mechanism LIPUS tooth movement (OTM) provide foundation for clinical application. Materials methods: We established rat model OTM evaluated rate by micro-CT immunohistochemical staining. In vitro, we isolated human marrow mesenchymal stem cells...