A5016422781- Asthma and respiratory diseases
- Drug-Induced Adverse Reactions
- Food Allergy and Anaphylaxis Research
- Allergic Rhinitis and Sensitization
- Contact Dermatitis and Allergies
- Respiratory and Cough-Related Research
- Dermatology and Skin Diseases
- Urticaria and Related Conditions
- Pediatric health and respiratory diseases
- Immunodeficiency and Autoimmune Disorders
- Indoor Air Quality and Microbial Exposure
- Autoimmune Bullous Skin Diseases
- Pharmaceutical studies and practices
- Pneumocystis jirovecii pneumonia detection and treatment
- Inhalation and Respiratory Drug Delivery
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Insects and Parasite Interactions
- Mast cells and histamine
- Heparin-Induced Thrombocytopenia and Thrombosis
- Parvovirus B19 Infection Studies
- Neonatal Respiratory Health Research
- Pharmacovigilance and Adverse Drug Reactions
- Poxvirus research and outbreaks
- Muscle and Compartmental Disorders
- Turkish Literature and Culture
Trakya University
2013-2023
ENT and Allergy
2020-2023
Eskişehir Osmangazi Üniversitesi Tıp Fakültesi Hastanesi
2018
Istanbul University
1998
Background: Atopic dermatitis (AD) is a common inflammatory skin disease with complex pathogenesis. Natural flavonoids exhibit strong anti-inflammatory and antioxidant properties in many human diseases. In this study, the potential bioactive effect of quercetin, polyphenolic plant-derived flavonoid, on AD model keratinocytes was evaluated. Methods: Immortalized HaCaT were treated interleukin (IL) -4, -13, tumor necrosis factor-α to mimic features vitro. Then effects quercetin inflammation,...
Environmental and dietary factors during pregnancy may affect development of infantile atopic dermatitis (AD). This study analyzed whether maternal consumption selected Turkish fermented foods (FF) other the AD first 2 years life.Eighty-four children with physician-diagnosed (aged between 24 months) mothers, 56 similarly aged, healthy mothers were studied. Physician-administered questionnaires retrospectively surveyed FF pregnancy. The intake frequency 8 was classified as either (1) daily or...
Abstract Background Food allergy is associated with stress, anxiety, and impairment in quality of life both children families. This study aimed to assess the anxiety mothers case suspected food their influence Internet usage on levels elimination. Methods Ninety‐two patients aged 0‐2 years presented at a pediatric department following either physicians' presumptive diagnosis or family's suspicion (Group 1) 99 healthy controls 2) were evaluated. The clinical was confirmed excluded by oral...
Drug reaction with eosinophilia and systemic symptoms (DRESS) is a drug-induced, severe multiorgan system whose exact pathogenesis remains unknown. This study aimed at evaluating specific changes in peripheral blood lymphocyte subtypes associated DRESS during antibiotic treatment. We analyzed six patients DRESS. A complete count lymphocytes immunophenotyping were carried out symptom onset follow-up visits. Acute-phase reactants liver enzymes measured all patients. Other tests - viral...
Atopic dermatitis is the most common chronic inflammatory skin disease. A complex interaction of both genetic and environmental factors thought to contribute disease.To evaluate whether single nucleotide polymorphisms in TLR2 gene c.2258C>T (R753Q) (rs5743708) c.-148+1614T>A (A-16934T) (rs4696480) (NM_0032643) are associated with atopic Turkish children.Case-control study.The study was conducted on 70 children aged 0.5-18 years. The clinical severity evaluated by scoring index. Serum total...
Successful management of childhood asthma requires a thorough idea the economic impact and its determinants, as policy makers physicians inevitably influence outcome. The aim this study was to define cost in Turkey determinants. In April 2006, multi-center, national performed where data regarding control levels were collected. Asthmatic children (6-18 yr) with at least 1-yr follow-up seen during 1-month period scheduled or unscheduled visits included. survey included questionnaire-guided...
Oral Abstracts O1 Functionally distinct HMGB1 isoforms correlate with physiological processes in drug-induced SJS/TEN Daniel F. Carr, Wen-Hung Chung, Rosalind E. Jenkiins, Mas Chaponda, Gospel Nwikue, Elena M. Cornejo Castro, J. Antoine, Munir Pirmohamed O2 Hypersensitivity reactions to beta-lactams, does the t cell recognition pattern influence clinical picture? Natascha Wuillemin, Dolores Dina, Klara K. Eriksson, Yerly O3 Specific binding characteristics of HLA alleles associated...
Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis are two rare but life-threatening diseases characterized by detachment of epidermis, bullous skin lesions mucous membrane erosions. Anti-epileptic drugs highly suspected to be the causative agents. Although carbamazepine (CBZ) is most associated anti-epileptic drug, oxcarbazepine (OXC), which a monohydrated derivative CBZ, proposed safer because different metabolism drugs. Herein, we report case SJS induced oxcarbazepine. A...
Background. The Childhood Asthma Control Test (C-ACT) has been proposed to be a simple, patient-based test that is able reflect the multidimensional nature of asthma control. In this analysis, aim was evaluate perceptions physicians and caregivers concerning C-ACT its predictive value for future asthma-related events. Method. multicenter prospective design, 368 children aged 4–11 years with who were either well- or not well-controlled included in study. study participants evaluated during...
Background Previous studies revealed there are many gaps in the awareness and knowledge regarding diagnosis management of drug allergy (DA) among various health-care professionals. Objective To assess knowledge, attitudes, practices towards DA residents interns 3 university hospitals region Trakya (Thrace), Turkey. Methods A cross-sectional survey was conducted at cities region: 1. University Medical Faculty, Edirne (n = 405), 2. Namik Kemal Tekirdag 114), 3. Canakkale 18 Mart 111). Turkish...