A5007004733- Bone Tissue Engineering Materials
- Human Health and Disease
- Vitamin D Research Studies
- Surgical Sutures and Adhesives
- Hemostasis and retained surgical items
- Endodontics and Root Canal Treatments
- Polymer Surface Interaction Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Radiation Dose and Imaging
- Electrospun Nanofibers in Biomedical Applications
- Facial Trauma and Fracture Management
- Oral Health Pathology and Treatment
- Supramolecular Self-Assembly in Materials
- Physical Education and Training Studies
- Diatoms and Algae Research
- Rheumatoid Arthritis Research and Therapies
- Tryptophan and brain disorders
- Enzyme Production and Characterization
- HIV/AIDS oral health manifestations
- Oral and gingival health research
- Healthcare Systems and Public Health
- Alkaline Phosphatase Research Studies
- Ultrasound and Hyperthermia Applications
- Immunodeficiency and Autoimmune Disorders
- Engineering Technology and Methodologies
Ural State Medical University
2015-2024
Background: Nanocomposite glycerohydrogels based on biocompatible elementcontaining glycerolates are of practicular interest for biomedical applications. Objective: Using two precursors, silicon and iron glycerolates, a new bioactive nanocomposite silicon‒iron hydrogel was obtained by sol-gel method. Methods: The composition structural features the were studied using complex modern analytical techniques, including TEM, XRD, AES. On example experimental animals hemostatic activity studied, as...
Background: Glycerolates of biogenic elements are interest because their pharmacological activity. Some them used as active substances in agents for topical application and biocompatible precursors sol-gel synthesis bioactive materials. Objective: In this work, morphostructural feature, ability to hydrolyze, the activity previously synthesized iron(III) monoglycerate were studied. Methods: Analytical techniques, including SEM, TEM, XRD, TGA, IR spectroscopy, DLS ELS, used. Hemostatic was...
Objective - analysis and generalization of the available data on manifestations human immunodeficiency virus in oral cavity depending number CD4+ T-lymphocytes blood. Materials methods. A search clinical studies, systematic reviews, online meta-analyses was conducted from 2004-2023 PubMed, Elsiever, Scopus, Cochrane, Elibrary databases, which described HIV infection as a function T-lymphocyte count. Results. Pseudomembranous candidiasis, hairy leukoplakia, Kaposi's sarcoma, non-Hodgkin's...
Doped with K + , Mg 2+ Fe Zn Mn Li Au 3+ SiO 2 nanocrystalline calcium carbonate-phosphate extends significantly the functionality for drug delivery: it can be used to speed up processes of bone repair and tissue strengthening.The advantage over other phosphate biomaterials is strengthening tooth tissues a human being any age, substances transported through skin restore broken bones in critically short period time regardless age.The mechanical fracture strength increases almost 5 times.These...
It is demonstrated that doped nanocrystalline calcium carbonate-phosphate a biocompatible material influences actively the osteogenesis bone repair in fractures, strengthening of tissues for drug delivery regardless age.The introduction carbonate-phosphates into animals increases 5 times mechanical strength tissue.The most durable may occur when silicon, iron and magnesium introduced an animal.The results obtained indicate possibility producing bioceramics based on carbonate-phosphates.
The use of glycerolates biogenic elements as biocompatible precursors in sol–gel synthesis is an innovative direction and opens up new scientific practical prospects chemistry technology producing practically important biomedical materials, including hemostatic, antimicrobial, wound healing materials. Using precursors, silicon, zinc, boron, iron glycerolates, bioactive nanocomposite hydrogels were obtained by the method. composition structural features studied using a complex modern...
Vitamin D has a variety of effects on oral tissues and organs. Cholecalciferol is involved in the processes formation enamel dentin, metabolism jaw bone tissue, local immunity antitumor reactions. The functional features vitamin reveal possibility dental pathology prevention. Objective. To study literature data effect organs using as drug prevention diseases. Materials methods. review analysis literary sources was carried out by keywords electronic resources Scopus, Web Science, MedLine,...
Doctors of various medical specialties often encounter adverse drug reactions in their clinical practice. Methotrexate (MTX) can cause the oral cavity, primarily erosions and ulcerations. The aim study was to analyse scientific literature on prevalence, pathophysiological mechanisms, risk factors for lesions associated with low doses MTX, prevention treatment. It demonstrated that most frequent MTX are hard-to-heal painful necrotic irregularly shaped mucosa (including aphthae ulcers)....
The possibility of obtaining an alloplastic biomaterial for the implant based on doped calcium carbonate-phosphates and polycaprolactone is studied. Nanocrystalline carbonate-phosphate with cations iron, magnesium, potassium, zinc, manganese, silicon intended bone repair by drug delivery investigated. Histological studies have revealed that samples after 60 days in a living organism are covered connective tissue capsule. formation blood vessels nerve endings observed
Studies (domestic and foreign) on the effect of vitamin D muscle strength, recovery rate, maximum oxygen consumption prevention skeletal injury reduction have been analyzed. At same time it was found that athletes are susceptible to hypovitaminosis no less often than standard population groups due higher physical loads. It is unequivocally possible say supplementation improves fitness can correct their condition in autumn-spring period. Objective: an analysis literature data based...
The paper presents the results of extended preclinical studies demonstrating safety using direct-acting antiviral drug Riamilovir in immature white rats. did not show any toxic effects on growth animals, their fertility, behavior, hematological and biochemical parameters, as well morphology visceral organs when used a course. According to studies, Ramilovir can be recommended for multicenter clinical trials adolescents children younger age groups.
Currently, iodine-containing compounds are used as x-ray contrast agents. Their significant drawback is the negative impact on organs and systems of human body. In this study, a new radiopaque agent, YTaO4 nanoparticles in suspension silicon dimethylglycerolate was investigated three types animals: outbred white mice, Wistar rats, Chinchilla rabbits. According to results toxicometry, observational data for entire experimental period after single 30-day administration suspension, substance...