A5054636564- Genetic diversity and population structure
- Cardiovascular and exercise physiology
- Cardiovascular Health and Disease Prevention
- Blood Pressure and Hypertension Studies
- Heart Rate Variability and Autonomic Control
- Ecology and Conservation Studies
- Gastric Cancer Management and Outcomes
- Plant Pathogens and Fungal Diseases
- Radiation Dose and Imaging
- Colorectal Cancer Screening and Detection
- CRISPR and Genetic Engineering
- Hepatocellular Carcinoma Treatment and Prognosis
- Plant and Fungal Species Descriptions
- Radioactive contamination and transfer
- Adipose Tissue and Metabolism
- Helicobacter pylori-related gastroenterology studies
- Diet and metabolism studies
- Molecular Biology Techniques and Applications
- Muscle Physiology and Disorders
- Salivary Gland Disorders and Functions
- Genomics and Phylogenetic Studies
- Shoulder Injury and Treatment
- Genetic Mapping and Diversity in Plants and Animals
- Sports Performance and Training
- Horticultural and Viticultural Research
Sapporo Medical University
2024-2025
Kyoto Koka Women's University
2024
Tokyo Metropolitan Institute of Gerontology
2005-2024
Kanagawa Children's Medical Center
2022-2024
Tokyo Medical and Dental University
2006-2024
Hirosaki University
2010-2023
Iwate Medical University
2022-2023
Chuo University
2023
The University of Tokyo
2011-2022
National Cancer Center Hospital East
2022
Recently cDNA encoding the histamine H3 receptor was isolated after 15 years of considerable research. However, several studies have proposed heterogeneity receptor. We report here molecular cloning and characterization a novel type A orphan G-protein-coupled named GPRv53 obtained through search human genomic DNA data base analyzed by rapid amplification ends (RACE). possessed features biologic amine receptors had highest homology with among known receptors. Mammalian cells expressing were...
To prospectively evaluate the safety and efficacy of combined unenhanced gadoxetic acid disodium (Gd-EOB-DTPA)-enhanced magnetic resonance (MR) imaging compared with MR triphasic contrast-enhanced spiral computed tomography (CT) for detection characterization focal liver lesions.The study was reviewed approved by institutional review board at each 15 centers involved in study, informed written consent given all patients. In total, 178 patients suspected hepatic lesions (based, most patients,...
Background: Resistance training has been increasingly incorporated into the overall exercise programme because of its effect on muscle strength, functional capacity and osteoporosis. High-intensity resistance increases arterial stiffness. However, moderate-intensity stiffness is unknown. Objective: To determine whether 12 weeks in middle-aged women. Methods: 35 women (age range 32 to 59 years) volunteered participate. The subjects were randomly assigned one three groups: (RT) group, aerobic...
Arterial stiffness is higher in strength-trained humans and lower endurance-trained humans. However, the mechanisms underlying these different adaptations are unclear. Vascular endothelium-derived factors, such as endothelin-1 (ET-1) nitric oxide (NO), play an important role regulation of vascular tonus. We hypothesized that endogenous ET-1 NO participate adaptation arterial types exercise training. The purpose this study was to investigate plasma concentrations strength- men. Young athletes...
In Arabidopsis, the two-dimensional expansion of leaves is regulated via polarized elongation cells. The ROTUNDIFOLIA3 (ROT3) protein, a member family cytochromes P450, involved in this process and regulates leaf length. Transgenic plants that overexpressed wild-type ROT3 gene had longer than parent plants, without any changes width. shapes floral organs were also altered, but stem, roots, hypocotyls was unaffected. To our knowledge, no similar specific regulation length has been reported...
For examination of sex- and age-specific relations between smoking risk type 2 diabetes mellitus, 39,528 nondiabetic men 88,613 women aged 40-79 years who underwent health checkups in Ibaraki-ken, Japan, 1993 were followed through 2002. Risk ratios for according to habits calculated using a Cox proportional hazards model. Compared with never smokers, the ratio among current after adjustment age, systolic blood pressure, antihypertensive mediation use, alcohol intake, parental history...
To reveal the present status and future directions of colorectal cancer in Asia. The Working Group consisted oncologists from six Asian countries (Japan, Korea, Hong Kong, China, Taiwan, Singapore Philippines) discussed 30th Asia-Pacific Cancer Conference made a consensus report. incidence has been increasing rapidly recent decades, mortality also increased except Japan Singapore. Colorectal screening with fecal occult blood tests is national policy Korea. Total colonoscopy most common...
Background:We examined the relationships of endurance and strength exercise training adolescent duration to arterial stiffness in young adult men. We hypothesized that adults participating sports would have decreased stiffness, whereas those strength-based increased stiffness. In addition, we predicted these trends be more pronounced with an increase sport participation.
The widely accepted paradigm that the modern genetic structure of plant species in northern hemisphere has been largely determined by recolonization from refugia after last glacial maximum fails to explain presence cold-tolerant at intermediate latitudes. Another generally is mountain ridges act as important barriers causing isolation species, but this too challenged recent studies. aims work reported here were determine diversity and distribution patterns extant natural populations an...
Obesity and reduction in central arterial distensibility, respectively, have been identified as powerful independent risk factors for cardiovascular disease. However, the effect of weight on function obese subjects has not yet clarified. We investigated whether low-calorie diet-induced affects distensibility endothelial middle-aged men. Twelve men (age: 45 ± 2 yrs, BMI: 30±1 kg/m ) completed a 12-week dietary intervention. Caloric restriction induced significantly loss decrease BMI. After...
Knowledge of the genetic structure and evolutionary history tree species across their ranges is essential for development effective conservation forest management strategies. Acer mono var. mono, an economically ecologically important maple species, extensively distributed in Northeast China (NE), whereas it has a scattered patchy distribution South (SC). In this study, demographic 56 natural populations A. were evaluated using seven nuclear microsatellite markers. Neighbor-joining STRUCTURE...
Aim Nursing and healthcare‐associated pneumonia ( NHCAP ) is a modified category of adjusted for the healthcare system J apan. The clinical characteristics risk factors mortality have not been well characterized in elderly patients with . Methods We retrospectively investigated 960 consecutive aged ≥65 years admitted pneumonia. Baseline characteristics, severity, pathogen distribution, outcomes were compared between community‐acquired CAP those applicability age, dehydration, respiratory...
The left ventricle morphologically adapts to endurance exercise training (eccentric cardiac remodeling) and strength (concentric remodeling). In addition, the acceleration of vagally mediated heart rate (HR) recovery after is one functional adaptations in endurance-trained humans. However, effect on HR unclear. Purpose: purpose this study was investigate whether postexercise accelerates strength-trained athletes. Methods: Subjects were young athletes (ST; N = 12), (ET; age-matched sedentary...
In many tree breeding programs, plus trees have been selected according to growth rate or stern form in trees. Trees that a high good do not always produce industrially desirable wood. Therefore criteria for wood quality should be considered programs. The objective of this study is obtain the basic knowledge Paraserianthes falcataria , an important commercial species Indonesia. Variation growth, log properties, density, and fiber length 13-year-old P. was investigated. Even though all were...
Effective arterial elastance (Ea), an index of load, increases with elevations in left ventricular to maximize the efficiency stroke work during exercise. Systemic compliance (C) and vascular resistance (R) are primary components contributing Ea, R plays a greater role determining Ea at rest. We hypothesized that contribution C exercise maintain optimal balance between load elastance, increase is due primarily reduction C.The aim this study was investigate contributions exercise.Ea (0.9 x...