A5050829732- MicroRNA in disease regulation
- Air Quality and Health Impacts
- Blood Coagulation and Thrombosis Mechanisms
- Circular RNAs in diseases
- Molecular Biology Techniques and Applications
- Advanced Chemical Sensor Technologies
- Reproductive Health and Contraception
- Telomeres, Telomerase, and Senescence
- Bacteriophages and microbial interactions
- Climate Change and Health Impacts
- Cancer-related molecular mechanisms research
- Biochemical Analysis and Sensing Techniques
- Venous Thromboembolism Diagnosis and Management
- Hepatitis B Virus Studies
- Olfactory and Sensory Function Studies
- Energy and Environment Impacts
University of Ostrava
2021-2025
Abstract Background Air pollution is associated with adverse health effects, especially on the respiratory and cardiovascular systems, but according to recent research, even in cognitive health, metabolic, immune systems. The objective was analyse effect of long-term exposure air selected system parameters, 8-isoprostane a parameter oxidative stress, alpha-1-antitrypsin protease inhibitor. Methods number 381 probands aged 35–65 from two differently polluted regions included. Lifetime...
Lung carcinoma is one of the most common malignancies worldwide. At present, unfortunately, there are no markers that would allow early identification this tumor in preclinical or clinical stage. The use sniffer dogs has been reported to show some promise diagnosis type cancer Aim: This study aimed evaluate possibility utilizing changes heart rate (which increases when finding a positive sample) detection. double-blinded pilot included two dogs. A chest strap was fastened on dog's chests for...
Thrombophilic mutations in genes for factor V Leiden and II prothrombin are among the most important risk factors developing thromboembolic disease (TED), along with use of oral contraceptives (OCs) or smoking.This study aimed to investigate occurrence young women using droplet digital PCR (ddPCR) and, based on results this investigation, perform a cost-benefit analysis ddPCR-based screening starting take OCs compared treatment costs patients who develop preventable TED Czech Republic.In...
The noninvasive collection of saliva samples for DNA analyses is simple, and its potential research diagnostic purposes great. However, isolates from such are often inferior quality to those blood.The aim this study was investigate the robustness sensitivity ddPCR instrument genetic poor by comparing their results obtained using an established method blood samples.Blood were collected 47 university students, which followed manual isolation analysis on droplet digital PCR (ddPCR). Results...