Introduction and purpose: Light is one of the defining features life on Earth, allowing certain biological processes to be subordinated its presence absence. With introduction artificial light, human natural clock was dysregulated. Apart from that, studies showed a connection between exposure light at night (ALAN) carcinogenesis. The aim this review present currently available knowledge in online database PubMed about Association Between Artificial Night Breast Prostate Cancer Risk Brief...

Introduction and purpose: Acromegaly is a rare disease which occurs with the frequency of 0.2-1.1 cases per 100 000 patients year. The main cause excess level growth hormone (GH) stimulates liver to insulin-like factor type 1 (IGF-1) secretion. IGF-1 leads tissues overgrowth. In addition, acromegalic suffer from many comorbidities, such as: cardiovascular, endocrinological, neoplastic musculoskeletal complications. aim this review update latest information concerning cardiovascular...

Introduction and purpose: Modern medical knowledge has grown to a vastness incomprehensible for single health professional learn accommodate. The usage of modern information technologies comes help, one them being artificial intelligence, branch computer science aimed at developing solutions perform tasks similar the human brain, but more efficient complex, without actual intervention. goal this review is provide reader with how intelligence applied in various branches medicine.
 Brief...

Introduction and purpose: Management of polycystic ovary syndrome (PCOS) is difficult since the exact pathogenic mechanism has not been established yet. Due to that fact, substances registered treat PCOS are still lacking efficacy associated with a number adverse effects. The aim this study review new possible treatment approaches.
 
 State knowledge: Inositol administered alone or combined oral contraceptive drugs improves patients’ hormonal status alleviates weight increase in...

Introduction: Primary membranous nephropathy (PMN) is a common cause of nephrotic syndrome in adults, characterized by the deposition immune complexes glomerular basement membrane.
 Aim this study: evaluate features PMN such as incidence, pathology, clinical and assess effectiveness immunosuppressive therapy.
 Materials Methods: The review was based on articles found PubMed database, using keyword „primary nephropathy” with appropriate sufixes.
 Results: challenging disease...

Introduction: Cardiovascular diseases (CVDs) are a significant health concern globally, including in Poland. Physical activity has been identified as crucial preventive factor for CVDs, and access to public sports infrastructure plays vital role promoting physical activity. However, the relationship between such its impact on cardiovascular outcomes Poland remains understudied.
 Aim of study: This study aims investigate prevalence mortality rates Poland.
 Materials methods:...

Background: Benzo(a)pyrenes are organic compounds from the polycyclic aromatic hydrocarbons group known for their carcinogenic properties. formed as a result of incomplete combustion matter, such biomass or fossil fuel.Aim study: To investigate whether respiratory diseases and malignant neoplasm-related deaths correlate to air concentrations benzo(a)pyrene in European countries.Material methods: Publicly available data were obtained regarding concentration EUROSTAT database, well territorial...

Introduction: Particulate matter (PM) as a part of outdoor air pollutants are classified human carcinogens. They formed majorly result combustion process by industry, power plants and engines. PM can be divided the size their particles into PM2.5 PM10, where small enough to penetrate alveoli sacs in lung reaching bloodstream, whereas PM10 affect mostly oral cavity, nose throat.
 Aim study: This study aims investigate impact particle concentrations EU NUTS 2 subregions on death rates due...

Introduction
 Hypertrophy is the process of increasing mass a tissue. In this article, we focused on impact mechanisms muscle hypertrophy, its effect human body, correlation with course diseases and tolerance treatment. We considered benefits having well-developed, also touched problems underdeveloped mass.
 Results
 The main factors causing hypertrophy are resistance exercise training, mechanotransduction, metabolic pathways, ribosomal biogenesis, gene expression hormones....

Introduction: Medullary thyroid carcinoma is a primary neoplasm originating from C cells. It can be familial or sporadic. The form associated with multiple endocrine neoplasia (MEN) syndrome types 2A and 2B caused by mutation in the RET gene, which encodes tyrosine kinase receptor. Treatment of medullary cancer mainly based on surgical resection gland, usually total thyroidectomy. followed-up chemotherapy, has limited efficacy. Hence, there growing interest new molecular therapies, such as...

Introduction and purpose: Male hypogonadism is diagnosed in patients with total testosterone under 9-12nmol/L (250-350ng/dl) serum which associated numerous symptoms can severely lower the quality of life. Due to cause levels gonadotropins it be divided hypergonadotropic hypogonadotropic hypogonadism. Hypogonadotropic occurs far less often, but it’s considered remain underdiagnosed. The purpose this study review most inborn diseases that involve as one their components.Current state...

Introduction and purpose: Total lack of testosterone or its level lower than 9-12 mmol/L (250-350 ng/dL) serum in men is called hypogonadism. Due to the importance male body, hypogonadism usually causes a variety symptoms, mostly sexual nature – libido, erectile dysfunction, infertility associated psychological problems, it can though be cause more dangerous changes body. The purpose this study review possible systemic complications (with emphasis on hypogonadotropic hypogonadism) apart from...

Adult-onset Still's disease (AOSD) is an uncommon condition that presents itself as difficult to diagnose, due non-specific symptoms and the necessity exclude any underlying causes. We present a case of 65-year-old man with slight fever, loss weight, pain stiffness joints. After successful diagnosis, corticosteroids were administered, which resulted in rapid improvement patient.

Acromegaly is a relatively rare disease, with the incidence of 0.2 - 1.1 cases in 100 000 people per year. Increased secretion growth hormone (GH) main pathomechanism. GH stimulates liver to insulin-like factor type 1 (IGF-1) production. It leads tissues overgrowth, facial changes, metabolic and cardiovascular comorbidities, such as diabetes, hyperthyroidism, or hypertension. The aim this review provide most up date knowledge about epidemiology risk factors neoplasms which occur more often...

Monkeypox is an emerging zoonotic disease caused by the monkeypox virus with a presentation similar to smallpox. Being previously endemic Africa, now spreading across world, causing fear of potential next pandemic. Smallpox vaccine, providing cross-immunity virus, due cessation vaccinations, decline in immunity against these viruses. Defined ways transmission are animal-to-human through consumption or attack affected animal, human-to-human close contact, via respiratory droplets. Currently,...

INTRODUCTION AND PURPOSE
 Recent studies have shown that changes in the microbiome, probiotic and antibiotic supplementation, can significantly modulate various forms of neuropsychiatric disorders - such as depression, anxiety stress-related disorders. There is growing body evidence pointing to a bidirectional correlation along brain-gut microbiota line. This axis connected through endocrine, immune neuronal pathways. The nerves make up enteric nervous system transmit modifications...

Introduction and purpose: Prostate cancer (PCa) as one of the most frequent neoplasms in men remains a challenge for oncologists. The main strategy its treatment is Androgen Deprivation Therapy (ADT) principle which an inducement hypogonadism. lack testosterone not only factor greatly contributing to decrease quality life overall, but additionally it increases odds complications, including low libido erectile disfunction, metabolic abnormalities, high cardiovascular risk, osteoporosis,...