Kevin O’Laughlin
A5082848320- Poxvirus research and outbreaks
- Herpesvirus Infections and Treatments
- Bacillus and Francisella bacterial research
- SARS-CoV-2 detection and testing
- COVID-19 epidemiological studies
- SARS-CoV-2 and COVID-19 Research
- Smoking Behavior and Cessation
- COVID-19 Clinical Research Studies
- COVID-19 and healthcare impacts
- Legionella and Acanthamoeba research
- Long-Term Effects of COVID-19
- Vaccine Coverage and Hesitancy
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Restraint-Related Deaths
- Biosensors and Analytical Detection
- Heme Oxygenase-1 and Carbon Monoxide
- COVID-19 diagnosis using AI
- Cannabis and Cannabinoid Research
- Mosquito-borne diseases and control
- Sports Analytics and Performance
- Cardiac Arrest and Resuscitation
- Auditing, Earnings Management, Governance
- Ocular Infections and Treatments
- Chemical Looping and Thermochemical Processes
- Bartonella species infections research
Centers for Disease Control and Prevention
2020-2024
National Center for Emerging and Zoonotic Infectious Diseases
2021-2023
Epidemic Intelligence Service
2020-2022
Computer Emergency Response Team
2021-2022
Centers for Disease Control and Prevention
2022
Stanford University
2022
Colorado Permanente Medical Group
2022
Emory University
2021
National Center for Immunization and Respiratory Diseases
2021
Public Health Institute
2021
The first reported U.S. case of coronavirus disease 2019 (COVID-19) was detected in January 2020 (1).As June 15, 2020, approximately 2 million cases and 115,000 COVID-19-associated deaths have been the United States.*Reports patients hospitalized with SARS-CoV-2 infection (the virus that causes COVID-19) describe high proportions older, male, black persons (2-4).Similarly, when comparing catchment area populations or nonhospitalized COVID-19 patients, underlying conditions, including...
CDC, the Food and Drug Administration (FDA), state local health departments, public clinical partners are investigating a multistate outbreak of lung injury associated with use electronic cigarette (e-cigarette), or vaping, products. In late August, CDC released recommendations for care providers regarding e-cigarette, product (EVALI) based on limited data from first reported cases (1,2). This report summarizes national surveillance describing features more recently interim these U.S. caring...
Electronic cigarettes (e-cigarettes), also called vapes, e-hookas, vape pens, tank systems, mods, and electronic nicotine delivery systems (ENDS), are devices that produce an aerosol by heating a liquid typically containing nicotine, flavorings, other additives; users inhale this into their lungs (1). E-cigarettes can be used to deliver tetrahydrocannabinol (THC), the principal psychoactive component of cannabis Use e-cigarettes is commonly vaping. Lung injury associated with e-cigarette...
¶ A list of severe manifestations monkeypox can be found at https://emergency
Currently, no Food and Drug Administration (FDA)-approved treatments for human monkeypox are available. Tecovirimat (Tpoxx), however, is an antiviral drug that has demonstrated efficacy in animal studies FDA-approved treating smallpox. Use of tecovirimat treatment the United States permitted only through FDA-regulated Expanded Access Investigational New (EA-IND) mechanism. CDC holds a nonresearch EA-IND protocol facilitates access to use monkeypox.§ The includes patient adverse event...
As of October 11, 2022, a total 26,577 monkeypox cases had been reported in the United States.* Although most are self-limited, lesions that involve anatomically vulnerable sites can cause complications. Ocular occur when Monkeypox virus (MPXV) is introduced into eye (e.g., from autoinoculation), potentially causing conjunctivitis, blepharitis, keratitis, and loss vision (1). This report describes five patients who acquired ocular during July-September 2022. All received treatment with...
CDC, the Food and Drug Administration, state local health departments, other public clinical stakeholders are investigating a national outbreak of electronic-cigarette (e-cigarette), or vaping, product use-associated lung injury (EVALI) (1). As October 22, 2019, 49 states, District Columbia (DC), U.S. Virgin Islands have reported 1,604 cases EVALI to including 34 (2.1%) EVALI-associated deaths in 24 states. Based on data collected as 15, this report updates patient characteristics substances...
In July 2019, the Illinois Department of Public Health and Wisconsin Services launched a coordinated epidemiologic investigation after receiving reports several cases lung injury in previously healthy persons who reported electronic cigarette (e-cigarette) use, or vaping (1). This report describes features e-cigarette product use by patients Wisconsin. Detailed patient interviews were conducted telephone, person, via Internet with 86 (68%) 127 patients. Overall, 75 (87%) interviewed using...
Monkeypox virus (MPXV) is an orthopoxvirus in the Poxviridae family. The current multinational monkeypox outbreak has now spread to 96 countries that have not historically reported monkeypox, with most cases occurring among gay, bisexual, and other men who sex (1,2). first case United States associated this was identified May 2022 Massachusetts (1); been all 50 states, District of Columbia (DC), one U.S. territory. MPXV transmitted by close contact infected persons or animals; infection...
Since May 2022, approximately 20,000 cases of monkeypox have been identified in the United States, part a global outbreak occurring 90 countries and currently affecting primarily gay, bisexual, other men who sex with (MSM) (1). Monkeypox virus (MPXV) spreads from person to through close, prolonged contact; small number occurred populations are not MSM (e.g., women children), testing is recommended for persons meet suspected case definition* CDC previously developed five real-time polymerase...
We report 2 immunocompetent and otherwise healthy adults in the United States who had monkeypox required hospitalization for viral myocarditis. Both patients were unvaccinated against orthopoxviruses. They shortness of breath or chest pain elevated cardiac biomarkers. No immediate complications observed. discharged home after symptoms resolved.
Melioidosis, caused by
Abstract Background Acanthamoeba is a free-living ameba that can cause severe disease affecting the central nervous system, skin, sinuses, and other organs, particularly in immunocompromised individuals. These rare but infections are often fatal, yet incompletely described. Methods Cases included were either reported to Centers for Disease Control Prevention (CDC) Free-Living Ameba program or published scientific literature. Characteristics of all patients United States with...
Abstract The SARS-CoV-2 Delta variant, first identified in October 2020, quickly became the dominant variant worldwide. We used publicly available data to explore relationship between illness and death (peak case rates, case-fatality rates) selected predictors (percentage vaccinated, percentage of population >65 years, density, testing volume, index mitigation policies) 45 high-income countries during wave using rank-order correlation ordinal regression. During Delta-dominant period, most...
Determining the incubation period of Oropouche virus disease can inform clinical and public health practice. We analyzed data from 97 travel-associated cases identified by Centers for Disease Control Prevention (n = 74) or GeoSentinel Network 13) 10 published literature. Using log-normal interval-censored survival analysis, we estimated median to be 3.2 (95% CI 2.5-3.9) days. Symptoms developed 1.1 0.6-1.5) days 5% patients, 9.7 6.9-12.5) 95% 15.4 9.6-21.3) 99% patients. The range 1-10 used...
This study describes the point prevalence of polymerase chain reaction tests positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among residents a sample Connecticut nursing homes in first half May 2020.
Abstract We compared the characteristics of hospitalized and nonhospitalized patients who had coronavirus disease in Atlanta, Georgia, USA. found that risk for hospitalization increased with a patient's age number concurrent conditions. also potential association between high hemoglobin A1c levels persons diabetes.
Abstract Viral genomic surveillance has been a critical source of information during the COVID-19 pandemic, but publicly available data can be sparse, concentrated in wealthy countries, and often made public weeks or months after collection. We used viral submitted to GISAID GenBank examine sequencing coverage lag time submission 2020–2021. compared sequences by country with reported infection rates population also examined based on country-level World Bank income status Health Organization...
Primary amebic meningoencephalitis is a rare, usually fatal disease, caused by Naegleria fowleri. This case highlights the challenging clinicopathologic diagnosis in 13-year-old boy who swam freshwater northern Florida where previous had exposure to body of water on same property 2009.
Abstract We evaluated the performance of self-collected anterior nasal swab (ANS) and saliva samples compared with healthcare worker–collected nasopharyngeal specimens used to test for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). same PCR diagnostic panel all from participants at a public hospital in Atlanta, Georgia, USA. Among 1,076 participants, 51.9% were men, 57.1% >50 years age, 81.2% Black (non-Hispanic), 74.9% reported >1 chronic medical condition. In total, 8.0%...
Self-collected specimens can expand access to SARS-CoV-2 testing. At a large inner-city hospital 1,082 participants self-collected saliva and anterior nasal swab (ANS) samples before healthcare workers collected nasopharyngeal (NPS) on the same day. To characterize patient preferences for self-collection, this investigation explored ability, comfort, ease of ANS self-collection testing along with associated characteristics, including medical history symptoms COVID-19. With nearly all...
The SARS-CoV-2 Delta variant emerged shortly after COVID-19 vaccines became available in 2021. We describe breakthrough infections a highly vaccinated, well-monitored US Embassy community Kampala, Uganda. Defining infection rates vaccinated populations can help determine public health messaging, guidance, and policy globally.
Abstract Background Multidrug-resistant (MDR) Shigella sonnei infections are a serious public health threat, and outbreaks common among men who have sex with (MSM). In February 2020, Australia’s Department of Health notified CDC extensively drug-resistant (XDR) S. in 2 Australian residents linked to cruise that departed from Florida. We describe an international outbreak XDR report on trends MDR the United States. Methods departments (HDs) submit every 20th isolate CDC’s National...
We aimed to describe frequency of COVID-19 exposure risk factors among patients presenting for medical care at an urban, public hospital serving mostly uninsured/Medicare/Medicaid clients and associated with SARS-CoV-2 infection. Consenting, adult seeking a from August November 2020 were enrolled in this cross-sectional investigation. Saliva, anterior nasal nasopharyngeal swabs collected tested using RT-PCR. Participant demographics, close contact, activities ≤14 days prior enrollment...