Atul Kumar

ORCID: 0000-0001-9578-2823
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About
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Research Areas
  • Epigenetics and DNA Methylation
  • Hedgehog Signaling Pathway Studies
  • Cancer-related Molecular Pathways
  • Chromatin Remodeling and Cancer
  • Cancer Cells and Metastasis
  • Cancer, Hypoxia, and Metabolism
  • Biochemical and Molecular Research
  • Traumatic Brain Injury Research
  • Metabolism, Diabetes, and Cancer
  • Optical Coherence Tomography Applications
  • Cancer Immunotherapy and Biomarkers
  • Immunotherapy and Immune Responses
  • Immune Response and Inflammation
  • Polymer Nanocomposite Synthesis and Irradiation
  • Cytokine Signaling Pathways and Interactions
  • CAR-T cell therapy research
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Photoacoustic and Ultrasonic Imaging
  • Cancer Genomics and Diagnostics
  • Cerebrospinal fluid and hydrocephalus
  • Conducting polymers and applications
  • interferon and immune responses
  • Advanced Fluorescence Microscopy Techniques

Indian Institute of Technology BHU
2025

Banaras Hindu University
2025

University of Alabama at Birmingham
2021-2024

Amity University
2021

Birla Institute of Technology, Mesra
2018

Elevated infiltration of immunosuppressive alternatively polarized (M2) macrophages is associated with poor prognosis in patients cancer. The tumor microenvironment remarkably orchestrates molecular mechanisms that program these macrophages. Here we identify a novel role for oncogenic Hedgehog (Hh) signaling programming signature metabolic circuitries regulate alternative polarization tumor-associated Two immunocompetent orthotopic mouse models mammary tumors were used to test the effect...

10.1158/0008-5472.can-20-1723 article EN Cancer Research 2021-07-21

Abstract The progressive number of old adults with cognitive impairment worldwide and the lack effective pharmacologic therapies require development non-pharmacologic strategies. photobiomodulation (PBM) is a promising method in prevention early or mild age-related impairments. However, it remains unclear efficacy PBM for patients significant dysfunction. In our study on male mice, we show gradual increase brain amyloid beta (Aβ) levels decrease drainage age, which, however, associated...

10.1007/s12200-025-00149-3 article EN cc-by Frontiers of Optoelectronics 2025-03-31

Optical coherence tomography (OCT) is a rapidly evolving, robust technology that has profoundly changed the practice of medical imaging. Swept source OCT (SSOCT) combines standard time domain and spatially encoded frequency OCT. We have employed high-speed SSOCT system utilizes swept laser with an A-scan rate 100 kHz central wavelength 1060 nm for imaging tissue. at allows high penetration in TiO2 nanoparticles (NPs) are mostly used various experimental purposes as exogenous contrast agent....

10.1088/1555-6611/aa9cc9 article EN Laser Physics 2018-02-06

PURPOSE The immune system of living being has evolved via the action defense mechanism by utilizing cells innate and adaptive immunity. Among these endothelial cell (EC) Immunity are least studied. ECs emerging as have some immunity features well. How EC can contribute to brain when implicated CD36 (an receptor) is widely unknown. METHODS To understand this question, we wanted investigate how regulates therefore created EC-specific knockout (KO) TRAP mice using several transgenic mouse lines...

10.1200/go-24-14400 article EN cc-by-nc-nd JCO Global Oncology 2024-07-01

<div>Abstract<p>Elevated infiltration of immunosuppressive alternatively polarized (M2) macrophages is associated with poor prognosis in patients cancer. The tumor microenvironment remarkably orchestrates molecular mechanisms that program these macrophages. Here we identify a novel role for oncogenic Hedgehog (Hh) signaling programming signature metabolic circuitries regulate alternative polarization tumor-associated Two immunocompetent orthotopic mouse models mammary tumors were...

10.1158/0008-5472.c.6513099.v1 preprint EN 2023-03-31
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