Chih‐Chuan Lin

ORCID: 0000-0001-9613-115X
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About
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Research Areas
  • Venomous Animal Envenomation and Studies
  • Rabies epidemiology and control
  • Poisoning and overdose treatments
  • Forensic Toxicology and Drug Analysis
  • Marine Invertebrate Physiology and Ecology
  • Pesticide Exposure and Toxicity
  • Psychedelics and Drug Studies
  • Heme Oxygenase-1 and Carbon Monoxide
  • Healthcare and Venom Research
  • Paraquat toxicity studies and treatments
  • Respiratory Support and Mechanisms
  • Airway Management and Intubation Techniques
  • Thermal Regulation in Medicine
  • Bioactive Natural Diterpenoids Research
  • Neonatal Health and Biochemistry
  • Amphibian and Reptile Biology
  • Pesticide and Herbicide Environmental Studies
  • Streptococcal Infections and Treatments
  • Yersinia bacterium, plague, ectoparasites research
  • Cardiac Arrest and Resuscitation
  • Restraint-Related Deaths
  • Alcohol Consumption and Health Effects
  • Traumatic Ocular and Foreign Body Injuries
  • Heavy Metal Exposure and Toxicity
  • Trauma and Emergency Care Studies

Chang Gung Memorial Hospital
2008-2024

Chang Gung University
2014-2024

Linkou Chang Gung Memorial Hospital
2013-2024

Keelung Chang Gung Memorial Hospital
2011

Institute of Biomedical Sciences, Academia Sinica
2011

Memorial Hospital
2011

In Southeast Asia, envenoming resulting from cobra snakebites is an important public health issue in many regions, and antivenom therapy the standard treatment for snakebite. Because these cobras share a close evolutionary history, amino acid sequences of major venom components different snakes are very similar. Therefore, either monovalent or polyvalent antivenoms may offer paraspecific protection against envenomation humans by several snakes. Taiwan, bivalent antivenom—freeze-dried...

10.1371/journal.pntd.0006138 article EN cc-by PLoS neglected tropical diseases 2017-12-15

ACADEMIC EMERGENCY MEDICINE 2011; 18:121–126 © 2011 by the Society for Academic Emergency Medicine Objectives: The objective was to determine diagnostic accuracy of procalcitonin measurement bacterial infections in patients with all causes liver cirrhosis. Methods: authors conducted a cross-sectional study 98 cirrhosis treated emergency department (ED) Chang-Gung Memorial Hospital, Taiwan. Serum levels and other clinical information were obtained concurrently. Patients assigned sepsis or...

10.1111/j.1553-2712.2010.00991.x article EN Academic Emergency Medicine 2011-01-01

Four types of antivenom are used to treat snakebites by the six species venomous snakes native Taiwan. Research into use in Taiwan and its outcomes, as well utility current Poison Control Center guidelines for use, has been limited. We aimed provide increased understanding investigating treatment outcomes patients treated snakebite Taiwan.On basis data collected from 2009 National Health Insurance database, with were identified categorized two sets groups according administered. The...

10.1016/j.jfma.2015.07.006 article EN cc-by-nc-nd Journal of the Formosan Medical Association 2015-08-04

Snakebites from Taiwan habus (Protobothrops mucrosquamatus) and green bamboo vipers (Viridovipera stejnegeri) account for two-thirds of all venomous snakebites in Taiwan. While there has been ongoing optimization antivenin therapy, the proper management superimposed bacterial wound infections is not well studied. In this Bacteriology Infections Taiwanese snake Envenomation (BITE) study, we investigated prevalence infection, bacteriology, corresponding antibiotic usage patients presenting...

10.3390/toxins12090575 article EN cc-by Toxins 2020-09-07

Wound necrosis and secondary infection are common complications after Naja atra bites. Clinical tools to evaluate the risk Taiwan cobra bites lacking. In this Cobra BITE study, we investigated prevalence of wound infection, bacteriology, corresponding antibiotic usage in patients presenting with snakebites. Patients lacking tissue were included developing score utilizing univariate multiple logistic regression, as require antibiotics for treatment. 8,295,497 emergency department visits...

10.3390/toxins13030183 article EN cc-by Toxins 2021-03-02

Introduction The use of new psychoactive substances (NPSs) has markedly increased worldwide; thus, it is important to monitor NPS-related effects. Taiwan Emergency Department Drug Abuse Surveillance (TEDAS) project aims assess the patterns recreational drug in patients presenting emergency departments (EDs) across country. Here, we report preliminary results this project.Methods This observational study included collection and analysis urine samples assessment clinical presentation from 79...

10.1080/15563650.2022.2038793 article EN cc-by-nc-nd Clinical Toxicology 2022-03-22

Rationale: Diabetic ketoacidosis is a serious and potentially life-threatening acute complication of diabetes mellitus (DM). Euglycemic diabetic (eDKA) however challenging to identify in the emergency department (ED) due absence marked hyperglycemia, often leading delayed diagnosis treatment. eDKA has been recently found be associated with sodium-glucose cotransporter 2 (SGLT2) inhibitors, one newest classes antidiabetics, though there are very limited reports implicating dapagliflozin as...

10.1097/md.0000000000011056 article EN cc-by-nc Medicine 2018-06-01

Peri-intubation cardiac arrest is an uncommon, serious complication following endotracheal intubation in the emergency department. Although several risk factors have been previously identified, this study aimed to comprehensively identify associated with peri-intubation arrest.This retrospective, nested case-control conducted from January 1, 2016 December 31, 2020 analyzed variables including demographic characteristics, triage, and pre-intubation vital signs, medications, laboratory data....

10.1016/j.ajem.2022.06.013 article EN cc-by The American Journal of Emergency Medicine 2022-06-11

Objective. To compare the effectiveness of ice packs and hot water immersion for treatment centipede envenomations. Methods. Sixty patients envenomated by centipedes were randomized into three groups treated with packs, immersion, or analgesia injection. The visual analog score (VAS) pain was measured before 15 min afterward. Demographic data on local systemic effects after bites collected. VAS scores decrease (ΔVAS) compared between groups. Results. All suffered from at affected sites;...

10.1080/15563650802084821 article EN Clinical Toxicology 2009-07-30

Background Synthetic cathinones (SC) are popular new psychoactive substances that produce sympathomimetic toxicity. Meth/amphetamine and SC have similar chemical structures pharmacological effects. We aimed to compare the clinical characteristics between meth/amphetamine users presenting emergency department (ED).Methods This retrospective observational cohort study included patients who presented six EDs from May 2017 April 2021 with symptoms related recreational drug use whose urine...

10.1080/15563650.2022.2062376 article EN Clinical Toxicology 2022-04-19

To determine a new pralidoxime (PAM) treatment guideline based on the severity of acute organophosphate intoxication patients, APACHE II score, and dynamic changes in serum butyrylcholinesterase (BuChE) activity. This is randomization trial. All patients received supportive care measurements atropinization. Each enrolled patient was treated with 2 gm PAM intravenously as loading dose. The control group according to WHO's recommended regimen, experimental their scores BuChE If patient's score...

10.1016/j.bj.2016.11.001 article EN cc-by-nc-nd Biomedical Journal 2016-12-01

The efficacy of hemoperfusion (HP) in patients with acute paraquat poisoning (PQ) remains controversial. We conducted a multi-center retrospective study to include PQ-poisoned admitted two tertiary medical centers between 2005 and 2015. used the Severity Index Paraquat Poisoning (SIPP) stratify severity patients. indication start HP was positive result for semiquantitative urine PQ test presentation hospital within 24 h. Early defined as first session performed five hours ingestion. A total...

10.3390/toxics8040084 article EN cc-by Toxics 2020-10-10

To compare gender differences in socio-demographics, clinical manifestations, and laboratory test results of individuals who visited emergency departments (EDs) involving drug use. We retrospectively collected the data from 10 hospitals Taiwan on drug-related ED visits May 2017 to December 2020. then examined their urine toxicological results, other tests using chi-square or multivariable logistic regression. Among with visits, there were 546 (73.7%) men 195 (26.3%) women. The most commonly...

10.1016/j.jfma.2022.03.007 article EN cc-by-nc-nd Journal of the Formosan Medical Association 2022-03-29

Emergency medical personnel are at risk of secondary contamination when treating victims chemical-biological-radiological-nuclear incidents. Hence, it is crucial to train them on the appropriate management patients involved in Personal protective equipment (PPE) plays an important role suffering from various types poisoning. However, very few studies have examined whether use PPE impedes airway emergency department setting. The present study evaluated effect physicians' performance using...

10.1097/mej.0000000000000157 article EN European Journal of Emergency Medicine 2014-05-23

Local tissue swelling, inflammation, and wound necrosis are observed in Taiwan cobra bites. Knowledge of the factors influencing local after bites might improve bite treatment strategy. Therefore, we aimed to explore This was a retrospective observational cohort study. All patients clinical presentations including serum venom levels for determining influential this study were obtained from Hung et al.'s previous Clinical features, such as information, initial patient presentation time,...

10.3390/toxins13050338 article EN cc-by Toxins 2021-05-07

10.1016/j.ajem.2007.02.014 article EN The American Journal of Emergency Medicine 2007-09-01

Predictors of mortality in illicit drug users involving Novel Psychoactive Substances (NPS) and multiple substances have not been elucidated. We aimed to define predictors the NPS endemic era’s strengthen patient care emergency treatment. This was a retrospective study. LC-MS/MS-confirmed positive who visited departments (ED) six medical systems were enrolled. Demographic information, physical examinations, laboratory data abstracted for analysis. There 16 fatalities 355 enrolled patients....

10.3390/toxics10070386 article EN cc-by Toxics 2022-07-12

Context Mortality prediction in paraquat poisoning is a major issue since most rules are inapplicable if the exact ingestion time cannot be determined and/or serum concentration not readily available, as countries. Therefore, we aimed to develop and validate new rule requiring these two parameters.Methods We designed 10-year observational cohort study including all consecutive paraquat-poisoned patients managed Taiwanese hospitals. built one define this rule. Parameters independently related...

10.1080/15563650.2021.1979234 article EN Clinical Toxicology 2021-09-20
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