In Southeast Asia, envenoming resulting from cobra snakebites is an important public health issue in many regions, and antivenom therapy the standard treatment for snakebite. Because these cobras share a close evolutionary history, amino acid sequences of major venom components different snakes are very similar. Therefore, either monovalent or polyvalent antivenoms may offer paraspecific protection against envenomation humans by several snakes. Taiwan, bivalent antivenom—freeze-dried...

ACADEMIC EMERGENCY MEDICINE 2011; 18:121–126 © 2011 by the Society for Academic Emergency Medicine Objectives: The objective was to determine diagnostic accuracy of procalcitonin measurement bacterial infections in patients with all causes liver cirrhosis. Methods: authors conducted a cross-sectional study 98 cirrhosis treated emergency department (ED) Chang-Gung Memorial Hospital, Taiwan. Serum levels and other clinical information were obtained concurrently. Patients assigned sepsis or...

Four types of antivenom are used to treat snakebites by the six species venomous snakes native Taiwan. Research into use in Taiwan and its outcomes, as well utility current Poison Control Center guidelines for use, has been limited. We aimed provide increased understanding investigating treatment outcomes patients treated snakebite Taiwan.On basis data collected from 2009 National Health Insurance database, with were identified categorized two sets groups according administered. The...

Snakebites from Taiwan habus (Protobothrops mucrosquamatus) and green bamboo vipers (Viridovipera stejnegeri) account for two-thirds of all venomous snakebites in Taiwan. While there has been ongoing optimization antivenin therapy, the proper management superimposed bacterial wound infections is not well studied. In this Bacteriology Infections Taiwanese snake Envenomation (BITE) study, we investigated prevalence infection, bacteriology, corresponding antibiotic usage patients presenting...

Wound necrosis and secondary infection are common complications after Naja atra bites. Clinical tools to evaluate the risk Taiwan cobra bites lacking. In this Cobra BITE study, we investigated prevalence of wound infection, bacteriology, corresponding antibiotic usage in patients presenting with snakebites. Patients lacking tissue were included developing score utilizing univariate multiple logistic regression, as require antibiotics for treatment. 8,295,497 emergency department visits...

Introduction The use of new psychoactive substances (NPSs) has markedly increased worldwide; thus, it is important to monitor NPS-related effects. Taiwan Emergency Department Drug Abuse Surveillance (TEDAS) project aims assess the patterns recreational drug in patients presenting emergency departments (EDs) across country. Here, we report preliminary results this project.Methods This observational study included collection and analysis urine samples assessment clinical presentation from 79...

Rationale: Diabetic ketoacidosis is a serious and potentially life-threatening acute complication of diabetes mellitus (DM). Euglycemic diabetic (eDKA) however challenging to identify in the emergency department (ED) due absence marked hyperglycemia, often leading delayed diagnosis treatment. eDKA has been recently found be associated with sodium-glucose cotransporter 2 (SGLT2) inhibitors, one newest classes antidiabetics, though there are very limited reports implicating dapagliflozin as...

Peri-intubation cardiac arrest is an uncommon, serious complication following endotracheal intubation in the emergency department. Although several risk factors have been previously identified, this study aimed to comprehensively identify associated with peri-intubation arrest.This retrospective, nested case-control conducted from January 1, 2016 December 31, 2020 analyzed variables including demographic characteristics, triage, and pre-intubation vital signs, medications, laboratory data....

Objective. To compare the effectiveness of ice packs and hot water immersion for treatment centipede envenomations. Methods. Sixty patients envenomated by centipedes were randomized into three groups treated with packs, immersion, or analgesia injection. The visual analog score (VAS) pain was measured before 15 min afterward. Demographic data on local systemic effects after bites collected. VAS scores decrease (ΔVAS) compared between groups. Results. All suffered from at affected sites;...

Background Synthetic cathinones (SC) are popular new psychoactive substances that produce sympathomimetic toxicity. Meth/amphetamine and SC have similar chemical structures pharmacological effects. We aimed to compare the clinical characteristics between meth/amphetamine users presenting emergency department (ED).Methods This retrospective observational cohort study included patients who presented six EDs from May 2017 April 2021 with symptoms related recreational drug use whose urine...

To determine a new pralidoxime (PAM) treatment guideline based on the severity of acute organophosphate intoxication patients, APACHE II score, and dynamic changes in serum butyrylcholinesterase (BuChE) activity. This is randomization trial. All patients received supportive care measurements atropinization. Each enrolled patient was treated with 2 gm PAM intravenously as loading dose. The control group according to WHO's recommended regimen, experimental their scores BuChE If patient's score...

The efficacy of hemoperfusion (HP) in patients with acute paraquat poisoning (PQ) remains controversial. We conducted a multi-center retrospective study to include PQ-poisoned admitted two tertiary medical centers between 2005 and 2015. used the Severity Index Paraquat Poisoning (SIPP) stratify severity patients. indication start HP was positive result for semiquantitative urine PQ test presentation hospital within 24 h. Early defined as first session performed five hours ingestion. A total...

To compare gender differences in socio-demographics, clinical manifestations, and laboratory test results of individuals who visited emergency departments (EDs) involving drug use. We retrospectively collected the data from 10 hospitals Taiwan on drug-related ED visits May 2017 to December 2020. then examined their urine toxicological results, other tests using chi-square or multivariable logistic regression. Among with visits, there were 546 (73.7%) men 195 (26.3%) women. The most commonly...

Emergency medical personnel are at risk of secondary contamination when treating victims chemical-biological-radiological-nuclear incidents. Hence, it is crucial to train them on the appropriate management patients involved in Personal protective equipment (PPE) plays an important role suffering from various types poisoning. However, very few studies have examined whether use PPE impedes airway emergency department setting. The present study evaluated effect physicians' performance using...

Local tissue swelling, inflammation, and wound necrosis are observed in Taiwan cobra bites. Knowledge of the factors influencing local after bites might improve bite treatment strategy. Therefore, we aimed to explore This was a retrospective observational cohort study. All patients clinical presentations including serum venom levels for determining influential this study were obtained from Hung et al.'s previous Clinical features, such as information, initial patient presentation time,...

Predictors of mortality in illicit drug users involving Novel Psychoactive Substances (NPS) and multiple substances have not been elucidated. We aimed to define predictors the NPS endemic era’s strengthen patient care emergency treatment. This was a retrospective study. LC-MS/MS-confirmed positive who visited departments (ED) six medical systems were enrolled. Demographic information, physical examinations, laboratory data abstracted for analysis. There 16 fatalities 355 enrolled patients....

Context Mortality prediction in paraquat poisoning is a major issue since most rules are inapplicable if the exact ingestion time cannot be determined and/or serum concentration not readily available, as countries. Therefore, we aimed to develop and validate new rule requiring these two parameters.Methods We designed 10-year observational cohort study including all consecutive paraquat-poisoned patients managed Taiwanese hospitals. built one define this rule. Parameters independently related...