- Traditional Chinese Medicine Analysis
- Pharmacological Effects of Natural Compounds
- Phytochemistry and Biological Activities
- Natural product bioactivities and synthesis
- Ginseng Biological Effects and Applications
- Food Quality and Safety Studies
- Analytical Chemistry and Chromatography
- Advanced Chemical Sensor Technologies
- Chromatography in Natural Products
- Inflammatory Bowel Disease
- Spinal Fractures and Fixation Techniques
- Fungal Biology and Applications
- Phytochemicals and Antioxidant Activities
- Environmental and Agricultural Sciences
- Ginger and Zingiberaceae research
- Forest, Soil, and Plant Ecology in China
- Cancer Immunotherapy and Biomarkers
- Medicinal Plant Pharmacodynamics Research
- Drug Solubulity and Delivery Systems
- Essential Oils and Antimicrobial Activity
- Inflammasome and immune disorders
- Flavonoids in Medical Research
- Polysaccharides and Plant Cell Walls
- Pesticide Residue Analysis and Safety
- Phytochemical compounds biological activities
Shanghai University of Traditional Chinese Medicine
2016-2025
Fujian Medical University
2025
Tobacco Research Institute
2009-2025
Longhua Hospital Shanghai University of Traditional Chinese Medicine
2007-2025
Fujian Agriculture and Forestry University
2025
Shandong Institute for Product Quality Inspection
2024-2025
Shandong University
2025
Mengchao Hepatobiliary Hospital
2025
Huazhong University of Science and Technology
2022-2024
Tongji Hospital
2022-2024
Metarhizium spp. are being used as environmentally friendly alternatives to chemical insecticides, model systems for studying insect-fungus interactions, and a resource of genes biotechnology. We present comparative analysis the genome sequences broad-spectrum insect pathogen anisopliae acridid-specific M. acridum. Whole-genome analyses indicate that structures these two species highly syntenic suggest genus evolved from plant endophytes or pathogens. Both acridum have strikingly larger...
Remodeling tumor immune microenvironment (TIME) is an important strategy to lift the immunosuppression and achieve normalization. In this work, a mannosylated lactoferrin nanoparticulate system (Man-LF NPs) developed for dual-targeting biomimetic codelivery of shikonin JQ1 via mannose receptor LRP-1 that are overexpressed in both cancer cells tumor-associated macrophages. The Man-LF NPs can serve as multitarget therapy inducing cell death cells, repressing glucose metabolism repolarizing...
Licorice has been used in Chinese folk medicine for the treatment of various disorders. biological capabilities detoxication, antioxidation, and antiinfection. In this study, we evaluated antihepatotoxic effect licorice aqueous extract (LE) on carbon tetrachloride (CCl(4))-induced liver injury a rat model. Hepatic damage, as reveled by histology increased activities serum aspartate aminotransferase (AST), alanine (ALT), alkaline phosphatase (ALP) activities, decreased levels total protein...
Why invasive plants are more competitive in their introduced range than native is still an unanswered question plant invasion ecology. Here, we used the model Solidago canadensis to test a hypothesis that enhanced production of allelopathic compounds results greater ability invaded rather range. We also examined degree which allelopathy contributes increased S. compared allelochemical by growing its area (the USA) and (China) populations were collected from two countries grown together...
Background Glioblastoma (GBM) treatment is undermined by the suppressive tumor immune microenvironment (TIME). Seek for effective methods brain TIME modulation a pressing need. However, there are two major challenges against achieving goal: first, to screen drugs with TIME-remodeling functions and, second, develop targeting system delivering drugs. Methods In this study, an α7 nicotinic acetylcholine receptors (nAChRs)-binding peptide D CDX was used modify codelivery liposomes achieve...
Abstract Diabetic wounds, which are a serious complication of diabetes, threat to most diabetic patients and there is lack satisfactory therapeutic strategies. Mesenchymal stem cell (MSC) spheroids under intensive investigation have emerged as particularly promising clinical therapy induce wound healing; however, applications MSC lagged because the difficulties related proper preparation, in situ instruction insufficient efficacy. Herein, novel Biotin‐ D FYIGSR supramolecular hydrogel...
In this study, ultrasound-assisted extraction of flavonoid from Crinum asiaticum was studied through response surface methodology (RSM) to gain the best process and enhance rate flavonoid. following RSM experiment, we selected corresponding data every factor as center point single-factor experiments, then experimental subjected multiple regression analysis. According statistical analysis results, results were consistent with polynomial model, determination coefficient (R2) 0.9769. The...
Atractylodes macrocephala Koidz. has been used as an invigorating spleen drug for eliminating dampness and phlegm in China. According to recent researches, different processing methods may affect the efficacy, so we collected A. from Zhejiang Province, produced with methods, crude (CA) bran-processed (BA), then analyzed its essential oils (EOs) by GC/MS. The results showed 34 components representing 98.44% of total EOs CA were identified, 46 98.02% BA identified. Atractylone is main...
Periodontitis is a complicated inflammatory disease that damages the tooth-supporting tissues, with limited pharmacotherapy available. Macrophage-targeting therapy promising for diseases. Resveratrol (RSV), nonflavonoid polyphenol, known its anti-inflammatory and immunomodulatory effects. However, medical application by poor stability water-solubility, as well low bioavailability.