A5004927312- Venous Thromboembolism Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Reproductive Health and Contraception
- Child and Adolescent Health
- Maternal and Perinatal Health Interventions
- Meta-analysis and systematic reviews
- Adolescent Sexual and Reproductive Health
- Global Maternal and Child Health
- Ethics in Clinical Research
- Health disparities and outcomes
- Prenatal Screening and Diagnostics
- Pregnancy and preeclampsia studies
- Cardiac Arrhythmias and Treatments
- Health Sciences Research and Education
- Acute Myocardial Infarction Research
- Maternal and fetal healthcare
- Employment and Welfare Studies
- Blood Coagulation and Thrombosis Mechanisms
- Folate and B Vitamins Research
- Maternal Mental Health During Pregnancy and Postpartum
- Assisted Reproductive Technology and Twin Pregnancy
- Urban, Neighborhood, and Segregation Studies
- scientometrics and bibliometrics research
- Breastfeeding Practices and Influences
Erasmus University Rotterdam
2016-2021
Erasmus MC
2016-2020
Amsterdam UMC Location University of Amsterdam
2011-2013
University of Amsterdam
2010
Rivaroxaban and dabigatran are new oral anticoagulants that specifically inhibit factor Xa thrombin, respectively. Clinical studies on the prevention treatment of venous arterial thromboembolism show promising results. A major disadvantage these is absence an antidote in case serious bleeding or when emergency intervention needs immediate correction coagulation. This study evaluated potential prothrombin complex concentrate (PCC) to reverse anticoagulant effect drugs.In a randomized,...
Geographical inequalities in perinatal health and child welfare require attention. To improve the identification, care, of mothers young children at risk adverse outcomes, HP4All-2 program was developed. The consists three studies, focusing on creating a continuum for selection tailored care pathways from preconception antenatal towards 1) postpartum 2) early childhood as well 3) interconception care. has been implemented ten municipalities Netherlands, aiming to target communities with...
Preconception care has been acknowledged as an intervention to reduce perinatal mortality and morbidity. However, utilization of preconception is low because awareness availability benefits the service. An outreach strategy was employed promote uptake consultations. Its effect on consultations evaluated within Healthy Pregnancy 4 All study.We conducted a community-based study. The for included four approaches: (1) letters from municipal health services; (2) general practitioners; (3)...
Objectives Successful implementation of preconception and interconception care contributes to optimizing pregnancy outcomes. While new mothers could potentially be provided by Preventive Child Health Care services, this is currently not routinely available in the Netherlands. The purpose study was identify facilitators barriers for services. Methods We organized four focus groups which physicians nurses, related health professionals policymakers participated. A semi-structured interview...
Background Most parents with young children pay routine visits to Well-Baby Clinics, or so-called Preventive Child Health Care (PCHC) services. This offers a unique opportunity promote and deliver interconception care. study aimed integrate such care perform an implementation evaluation. Methods In seven Dutch municipalities, PCHC professionals were instructed discuss the possibility of consultation during each six-months well-baby visit. The primary outcome this was coverage intervention,...
Purpose: To evaluate the effects of preconception care (PCC) consultations by change in lifestyle behaviors. Setting and Intervention: Women deprived neighborhoods 14 Dutch municipalities were encouraged to visit a general practitioner or midwife for PCC. Sample: The study included women aged 18 41 years who had PCC consultation. Design: In this community-based prospective cohort study, we assessed initiation folic acid supplementation, cessation smoking, alcohol consumption, illicit drug...
Vitamin K antagonists (VKA) are the only registered oral anticoagulants for treatment of venous thromboembolism (VTE). VKA have an unpredictable and highly variable effect on coagulation, with a high risk under- over-treatment. Novel anticoagulants, such as dabigatran rivaroxaban, could be very welcome replacement VKA, they show predictable anticoagulant effect. Results several phase II III studies shown efficacy safety rivaroxaban in prophylaxis VTE, prevention stroke atrial fibrillation....
Introduction: The potential value of preconception care and interconception is increasingly acknowledged, but delivery generally uncommon. Reaching women for potentially easier than care, however the concept still unfamiliar. Expert consensus could facilitate guidelines, policies subsequent implementation. A national international expert meeting were organized to discuss term, definition, content, relevant target groups, ways reach groups care.Methods: We performed a literature study develop...
Objective To investigate whether a structured inquiry during pregnancy of medical factors and social associated with low socioeconomic status, subsequent patient-centred maternity care could increase maternal empowerment. Design Cluster-randomised controlled trial. Setting This study was conducted among pregnant women in selected urban areas the Netherlands. part nationwide Healthy Pregnancy 4 All-2 programme. Population Pregnant listed at one sixteen participating organisations between July...
We appreciate the remarks made by Bernstein et al and Marlu al.In our study, a single dose of prothrombin complex concentrate (PCC) Cofact normalized anticoagulant effect rivaroxaban, but not that dabigatran, measured means coagulation assays in healthy subjects. 1We agree with comment these tests may insufficiently represent definitive beneficial patients hemorrhage.To establish PCCs as effective reversing agents for new oral anticoagulants, clinical data are required, indicated Discussion...
Living in deprivation is related to ill health. Differences health outcomes between neighbourhoods may be attributed neighbourhood socio-economic status (SES). Additional differences health, child wellbeing could also SES. Therefore, we aimed investigate the association deprivation, and social indicators of wellbeing.Aggregated data from 3565 390 municipalities Netherlands were eligible for analysis. Neighbourhood SES scores on used perform repeated measurements, with one year measurement...