Pedro Felipe Carvalhedo de Bruin

ORCID: 0000-0001-9694-1523
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About
Contact & Profiles
Research Areas
  • Sleep and related disorders
  • Obstructive Sleep Apnea Research
  • Sleep and Wakefulness Research
  • Restless Legs Syndrome Research
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Circadian rhythm and melatonin
  • Parkinson's Disease Mechanisms and Treatments
  • Neuroscience of respiration and sleep
  • Obesity, Physical Activity, Diet
  • Eating Disorders and Behaviors
  • Asthma and respiratory diseases
  • Respiratory Support and Mechanisms
  • Bipolar Disorder and Treatment
  • Cardiovascular and Diving-Related Complications
  • Acute Ischemic Stroke Management
  • Gestational Diabetes Research and Management
  • Cystic Fibrosis Research Advances
  • COVID-19 Clinical Research Studies
  • Health and Lifestyle Studies
  • Maternal Mental Health During Pregnancy and Postpartum
  • Children's Physical and Motor Development
  • Healthcare Regulation
  • Biochemical effects in animals
  • Cancer survivorship and care
  • Long-Term Effects of COVID-19

Universidade Federal do Ceará
2015-2024

Universidade de Fortaleza
2011-2021

Instituto do Sono
2011

Imperial College London
2001

Hammersmith Hospital
1993-1998

BACKGROUND--Ultrasound allows observation of the thickness diaphragm in zone apposition vivo during relaxation and maximum inspiratory efforts. METHODS--Changes were studied by B mode (two dimensional) ultrasound 13 healthy men aged 29-54 years seated position. A high resolution 7.5 MHz transducer was held perpendicular to chest wall line a right intercostal space between anteroaxillary mid-axillary lines observe 0.5-2 cm below costophrenic angle. The changes observed while breath holding at...

10.1136/thx.50.11.1157 article EN Thorax 1995-11-01

To investigate the presence of restless legs syndrome (RLS) and quality sleep in a population type 2 diabetic patients.The study was composed 100 consecutive patients regularly attending diabetes clinic at University Hospital Federal Ceará. The subjects' assessed by Pittsburgh Sleep Quality Index, excessive daytime sleepiness (EDS) measured Epworth Sleepiness Scale. RLS diagnosed using four minimum criteria defined International Restless Legs Syndrome Study Group. Other relevant clinical...

10.2337/diacare.28.11.2633 article EN Diabetes Care 2005-11-01

There is little information on the morphometric characteristics of diaphragm in patients with Duchenne muscular dystrophy.The thickness was measured at zone apposition using B mode ultrasonography 10 boys dystrophy mean (SD) age 10.3 (1.3) years and 12 normal controls 11.3 (2.0) during relaxation (DiTrelax) maximum effort inspiratory manoeuvres (DiTPimax) functional residual capacity.DiTrelax greater (1.74 (0.21) mm) than (1.48 (0.20) mm), difference (95% CI) 0.26 (0.08 to 0.44), despite...

10.1136/thx.52.5.472 article EN Thorax 1997-05-01

We have tested the hypothesis that restless leg syndrome (RLS) is related to quality of sleep, fatigue and clinical disability in multiple sclerosis (MS). The diagnosis RLS used four minimum criteria defined by International Restless Legs Syndrome Study Group. Fatigue was assessed Severity Scale (FSS >27), sleep Pittsburgh Sleep Quality Index (PSQI >6), excessive daytime sleepiness Epworth Sleepiness (ESS >10) Expanded Disability Status (EDSS). Forty-four patients (32 women) aged 14 64 years...

10.1590/s0100-879x2008001000017 article EN cc-by Brazilian Journal of Medical and Biological Research 2008-10-01

Truck drivers are more likely to suffer severe injury and death due certain truck driving characteristics. Identifying preventing factors associated with accidents in this population is important minimize damage improve road safety. Excessive daytime sleepiness a major public health problem, leading impaired cognitive function, reduced alertness, increased risk of motor vehicle crashes. The aim cross-sectional study was determine the prevalence predictors hypersomnolence (defined as an...

10.1080/07420520600920759 article EN Chronobiology International 2006-01-01

Chronic obstructive pulmonary disease (COPD), a major cause of death and disability, is attributed to an abnormal inflammatory response by the lungs noxious substances, primarily from cigarette smoke. Although oxidative stress regarded as central pathogenesis COPD, very few studies have examined effects antioxidants in this condition. This was randomized, double-blind, placebo-controlled study on melatonin COPD. Thirty-six consecutive patients with clinically stable moderate severe COPD (30...

10.1111/j.1600-079x.2012.00992.x article EN Journal of Pineal Research 2012-03-19

Medical students are at higher risk for depression, affecting not only their lives but also patient care. This article studied a population of medical engaged in lecture-based learning regarding the presence depressive symptoms and its relation to morningness-eveningness. Depressive were assessed by Beck Inventory scale (BDI>10), diurnal preference was Horne & Ostberg Morningness/Eveningness Questionnaire (MEQ). Family history depression involvement regular physical activity investigated. A...

10.1080/07420520701657730 article EN Chronobiology International 2007-01-01

There have been few studies of respiratory and limb muscle size function in middle-aged patients with asthma persistent airways obstruction. We compared the forces generated by thigh muscles their dimensions assessed ultrasound nine chronic (mean age 56 (SD 8) yrs; functional residual capacity/total lung capacity ratio (FRC/TLC) 60 (10)%), normal subjects (aged 53 (7) FRC/TLC 55 (5)%). Diaphragm thickness was measured at zone apposition B-mode during relaxation (DiTrelax) a maximum-effort...

10.1183/09031936.97.10010059 article EN European Respiratory Journal 1997-01-01

To investigate how treatment can affect airway dynamics and respiratory muscle strength in Parkinson's disease (PD), we assessed maximum effort inspiratory expiratory mouth pressures (MIP MEP), oscillatory impedance, flow-volume curves (MEFV MIFV) 10 patients (8 male 2 female; mean age 51 ± 5.3 yr, SD) after temporary interruption of antiparkinsonian therapy (off) during continuous subcutaneous infusion a direct stimulant dopamine receptors, apomorphine (on). Treatment improved neurologic...

10.1164/ajrccm/148.6_pt_1.1576 article EN American Review of Respiratory Disease 1993-12-01

OBJECTIVES: Subjective sleep complaints have been reported in up to 80% of patients with end stage renal disease (ESRD). In these patients, disturbances manifesting as insomnia, apnea syndrome, restless leg syndrome (RLS), periodic limb movement disorder and excessive daytime sleepiness (EDS) frequently reported. Moreover, studies about the role dialysis shift on abnormalities, morbidity mortality are still scarce. The aim this study was investigate influence quality abnormalities ESRD....

10.1590/s0104-42302007000600014 article EN cc-by Revista da Associação Médica Brasileira 2007-01-01

Disturbed sleep is common in chronic obstructive pulmonary disease (COPD). Conventional hypnotics worsen nocturnal hypoxemia and, severe cases, can lead to respiratory failure. Exogenous melatonin has somnogenic properties normal subjects and improve several clinical conditions. This randomized, double-blind, placebo-controlled study was carried out determine the effects of on COPD. Thirty consecutive patients with moderate very COPD were initially recruited for study. None participants had...

10.1590/s0100-879x2008001000016 article EN cc-by Brazilian Journal of Medical and Biological Research 2008-10-01
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