Krzysztof Lewandowski

ORCID: 0000-0001-9711-2372
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About
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Research Areas
  • Cardiac, Anesthesia and Surgical Outcomes
  • Toxic Organic Pollutants Impact
  • Aortic aneurysm repair treatments
  • Vascular Procedures and Complications
  • Cholinesterase and Neurodegenerative Diseases
  • Pesticide Exposure and Toxicity
  • Computational Drug Discovery Methods
  • Heparin-Induced Thrombocytopenia and Thrombosis
  • Mercury impact and mitigation studies
  • Microplastics and Plastic Pollution
  • Cardiac and Coronary Surgery Techniques
  • Antibiotic Resistance in Bacteria
  • Vibrio bacteria research studies
  • Microbial bioremediation and biosurfactants
  • Bone and Joint Diseases
  • GDF15 and Related Biomarkers
  • Antimicrobial Resistance in Staphylococcus
  • Bacterial Identification and Susceptibility Testing
  • Salmonella and Campylobacter epidemiology
  • Protein Degradation and Inhibitors
  • Biliary and Gastrointestinal Fistulas
  • Chemotherapy-induced organ toxicity mitigation
  • Cardiac Ischemia and Reperfusion
  • Intensive Care Unit Cognitive Disorders
  • Mollusks and Parasites Studies

John Paul II Hospital
2018-2025

Gdańsk Medical University
2011-2025

University of Gdańsk
2002-2020

University of Siedlce
2019

Norsk Hydro (Germany)
2016

Institute of Plant Genetics, Polish Academy of Sciences
2006

Gdańsk University of Technology
2002-2003

Medical University of Warsaw
2002

Poznan University of Medical Sciences
1997

ABSTRACT We present a case of acute clonal bone marrow 98% infiltration atypical myeloid cells with borderline hypogranular/agranular promyelocytes/myelocytes and occasional blast maturity, which also formed extramedullary tumours in the chest wall, isolated trisomy chromosome 6 pathogenic variant U2AF1 (S34F) that escapes established leukaemia (AML) diagnostic criteria according to World Health Organization (WHO) classification. Following standard daunorubicin cytarabine induction therapy,...

10.1111/jcmm.70461 article EN cc-by Journal of Cellular and Molecular Medicine 2025-03-01

Butyrylcholinesterase (BChE) activity assay and inhibitor phenotyping can help to identify patients at risk of prolonged paralysis following the administration neuromuscular blocking agents. The plays an important role in clinical chemistry as a good diagnostic marker for intoxication with pesticides nerve Furthermore, is also commonly used vitro characterization cholinesterases, their toxins drugs. There still lack standardized procedure measurement BChE many laboratories use different...

10.1371/journal.pone.0139480 article EN cc-by PLoS ONE 2015-10-07

There is increasing evidence that genetic variability influence patients’ early morbidity after cardiac surgery performed using cardiopulmonary bypass (CPB). The use of mortality as an outcome measure in surgical association studies rare. We publish the 30-day and 5-year survival analyses with focus on pre-, intra-, postoperative variables, biochemical parameters, variants INFLACOR (INFlAmmation Cardiac OpeRations) cohort.In a series prospectively recruited 518 adult Polish Caucasians who...

10.18388/abp.2017_2361 article EN cc-by Acta Biochimica Polonica 2018-04-25

Summary Introduction: According to the International Council for Standardization in Hematology (ICSH) guidelines standardization of bone marrow specimens and reports, smears from aspirates microscopic examination should be prepared using two techniques simultaneously: wedge‐spread crush technique. However, outcomes these have never been compared. Methods: We investigated 105 adult, haematologically healthy subjects, via both simultaneously. Results: Comparison revealed significant...

10.1111/j.1751-553x.2011.01387.x article EN International Journal of Laboratory Hematology 2011-12-07

Abstract Combustion processes are considered to be the main source of dioxin emission in Baltic region. Pentachlorophenol (PCP) and its derivatives, pentachlorophenyl laurate (PCPL) sodium pentachlorophenate (NaPCP) known as precursors dioxins. The research was conducted obtain first data on concentration PCDD/Fs PCP bottom sediments Port Gdansk. Toxicity (the Microtox® test) well several sediment parameters have been examined. In surface layer from Gdansk, all congeners detected using...

10.2478/s13545-014-0146-7 article EN cc-by-nc-nd Oceanological and Hydrobiological Studies 2014-09-01

Amplification of DNA fragments surrounding rare restriction sites (ADSRRS-fingerprinting) is a novel assay based on suppression polymerase chain reaction (PCR). This phenomenon allows the amplification only limited subset fragments, since those with two different oligonucleotides ligated at ends complementary strands are amplified in PCR. The can be easily analyzed polyacrylamide gels, stained ethidium bromide. We have implemented this method using set clinical Serratia marcescens isolates...

10.1016/s0928-8244(03)00149-4 article EN FEMS Immunology & Medical Microbiology 2003-05-27

The new data on the distribution o f m edicinal leech {Hirudo medicinalis L.) in Poland, collected years 1999-2007 during several hydrobiological and batrachological studies any regions are presented.In total, 87 records were found, w hich doubled num ber contem porary know n localities.H abitat preferences protected status this species Poland discussed.K ey rd

10.3161/00159301ff2008.51.2.079 article EN Fragmenta Faunistica 2008-01-01

Abstract Pentachlorophenol (PCP) is an anthropogenic substance, toxic to humans. The major source of this compound in the environment are wastes from factories producing PCP and materials (textiles, wood) treated with PCP. In 2008, a dossier was prepared support inclusion Annex I Protocol 1979 Convention on Long-Range Transboundary Air Pollution Persistent Organic Pollutants. draft decision add along its salts (NaPCP) esters (PCPL) A Stockholm adopted during seventh meeting Conference...

10.1515/ohs-2016-0033 article EN cc-by-nc-nd Oceanological and Hydrobiological Studies 2016-09-01

Study was undertaken to determine the effect of hydrostatic pressure on sorption pentachlorophenol (PCP). The experiment conducted at atmospheric (1000 hPa) and increased (6000 simulating conditions water depth 50 m. PCP examined in an artificial environment (microcosm) consisting marine bottom sediments from a Polish harbor southern Baltic Sea. first part comprised determination parameters microcosms (organic matter content, conductivity) overlying (pH, ion concentration) 1000 hPa. second...

10.1007/s11356-017-1076-x article EN cc-by Environmental Science and Pollution Research 2018-02-02

Abstract The Vistula River plays an important role in the supply of autochthonous and allochthonous material to Gulf Gdansk. suspended particulate matter (SPM) fluvial origin is considered constitute a specific sorbent for halogenated organic compounds due their lipophilic characteristics relative solubility. Because there are many factors affecting input SPM into estuarine environment Gdansk, e.g. hydrological River, it became necessary verify whether same processes may affect discharge...

10.1515/ohs-2016-0016 article EN cc-by-nc-nd Oceanological and Hydrobiological Studies 2016-06-01

Methotrexate is a cytostatic drug, folic acid antagonist, used in chemotherapy and immunosuppression adults children. Its use high doses an absolute indication for therapeutic drug monitoring. highly toxic requires dosage of specific antidote, calcium folinate. This rescue therapy helps to prevent methotrexate effects bone marrow suppression. Monitoring concentration also diagnose patients with decreased MTX elimination rate, who would benefit from glucarpidase treatment, enzyme which...

10.5604/01.3001.0013.7991 article EN Diagnostyka Laboratoryjna 2017-12-18

The occurrence of bivalves the family Unionidae was analysed in 16 ox-bow lakes Bug River (The Valley Landscape Park) years 2003-2005.One to four species were found 12 lakes.Unio pictorum (L.) dominating 5 and Anodonta anatina -in 3 lakes.Other frequent U. tumidus Philipsson A. cygnea (L.).U. crassus only one lakes.Most densities noticed around 10 ind./m 2 maximum density over 200 .

10.3161/00159301ff2006.49.1.069 article EN cc-by Fragmenta Faunistica 2006-01-01

Endovascular aneurysm repair as a minimally invasive alternative has become commonly used surgical method for treating patients with abdominal aortic (AAA).To analyze short-term outcomes of endovascular treatment AAA patients, including ruptured cases.From 2010 to 2015, 247 were treated using the technique. A analysis was conducted - up 30 days after surgery. It included 236 planned surgery and 11 operated on in emergency mode, due AAA.Rates mortality re-interventions among undergoing 2.5%...

10.5114/wiitm.2018.73358 article EN cc-by-nc-sa Videosurgery and Other Miniinvasive Techniques 2018-02-07

The endovascular method as a less invasive treatment for patients with abdominal aortic aneurysm (AAA) has become an alternative to conventional open surgery.The objective of the present study was analyse outcomes AAA in long-term observation.A group 236 subjected planned repair (EVAR) between 2010 and 2015 reviewed. Rates mortality, surgical complications re-interventions were collected separate time periods, i.e. up 30 days after surgery, 3 years, from 5 years surgery. Cumulative rates...

10.5114/wiitm.2020.93984 article EN cc-by-nc-sa Videosurgery and Other Miniinvasive Techniques 2020-04-20
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