A5103232111- Traditional Chinese Medicine Analysis
- Metabolomics and Mass Spectrometry Studies
- Sphingolipid Metabolism and Signaling
- Lipid Membrane Structure and Behavior
- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Fungal Biology and Applications
- Microbial Natural Products and Biosynthesis
- Tuberculosis Research and Epidemiology
- Cholesterol and Lipid Metabolism
- Ginger and Zingiberaceae research
- Phytochemical Studies and Bioactivities
- Mycorrhizal Fungi and Plant Interactions
- Phytochemistry and Bioactivity Studies
- Biochemical and Molecular Research
- Medicinal Plant Pharmacodynamics Research
- Erythrocyte Function and Pathophysiology
- Analytical Chemistry and Chromatography
- Bacterial Genetics and Biotechnology
- Genomics and Phylogenetic Studies
- Fermentation and Sensory Analysis
- Bioactive natural compounds
- RNA and protein synthesis mechanisms
- Silymarin and Mushroom Poisoning
- Sesquiterpenes and Asteraceae Studies
Twelfth Guangzhou City People's Hospital
2025
Guangdong Pharmaceutical University
2014-2021
Chinese Academy of Medical Sciences & Peking Union Medical College
2009
The 309th Hospital of Chinese People's Liberation Army
1998-2000
Queens College, CUNY
1995
The fragmentation regularities of five phospholipids have been studied by ultra-high-performance liquid chromatography electrospray ionization quadrupole time-of-flight tandem mass spectrometry.
Mushroom poisoning is a significant food safety issue with an increasing incidence, Southwest China being the most severely affected region. This study analyzed 112 cases of mushroom admitted to specialized toxicology hospital in Guangzhou City, Guangdong Province, China. A total 9 species were identified across 4 types. Among 51 incidents, gastroenteritis was common presentation. However, acute liver failure caused by lethal Amanita spp. accounted for all mortality this cohort. Shorter...
Abstract Pu‐erh tea is believed to be a beneficial beverage for health due its many kinds of pharmacological effects. Nevertheless, detailed information related differences in metabolites raw from different geographical origins remains scarce. In this study, 43 elements were found water‐soluble components by highly sensitive ultra‐performance liquid chromatography quadrupole time‐of‐flight mass spectrometry (U‐HPLC/Q‐TOF‐MS). The characteristic groups 29 nondestructive proton nuclear...
In the previous work we reported five lanostane-type triterpenes from CHCl3 soluble fraction of Fomes officinalis. further study on isolation constituents fraction, four new triterpenes, fomefficinic acids F (1), G (2) and fomefficinols A (3), B (4), together with seven known compounds officinalic acid (5), fomlactone (6), (7), C (8), laricinolic (9), ergosterol (10), ergota-7,22,dien-3β-ol (11) were isolated. The structures determined by spectroscopic analyses chemical methods including NMR...
cls and nov mutants have similar increased sensitivities to novobiocin reduced levels of cardiolipin, both which can be corrected by plasmid-borne copies either wild-type gene. A comparison the DNA sequences genes further verifies their identity.
Coumarins is a kind of important components in traditional Chinese medicine. Due to their special structure, they have significant pathological connections with many diseases. In this research, we established rapid method analyse the coumarins from Fructus citri Sarcodactylis by using technique ultra-performance liquid chromatography quadruple time-of-flight mass spectrometry. Twenty-one were identified Sarcodactylis, 10 discovered for first time. At same time, sensitive identifying was established.
Abstract Alpinia officinarum is used for its anti‐inflammatory activity historically in China. Diarylheptanoids isolated from A. play important biological roles the prevention and treatment of inflammatory disorders. Seven diarylheptanoids (1–7) were . The cell viabilities activities evaluated by MTT assay tumor necrosis factor‐ α production Kdo2‐lipid A‐stimulated RAW 264.7 cells vitro relationships between their anti‐inflammatories structure‐activities are discussed. results indicated that...
ABSTRACT The study aims to develop a rapid, sensitive ultra‐performance liquid chromatography coupled with an electrospray ionization quadruple time‐of‐flight tandem mass spectrometry (UPLC/Q‐TOF‐MS) analytical method for identifying glycerophospholipids (GPLs) from RAW264.7 cells. A total of 78 GPLs including 22 phosphatidylethanolamines (PEs), 49 phosphatidylcholines (PCs), four phosphatidylglycerols, one phosphatidylinositol and two unknown were identified. PC (14:0/16:1), (14:0/16:0), PE...
A rapid, sensitive, and reliable approach for analyzing five kinds of erythrocyte phospholipids in Sprague-Dawley rats was provided by ultra high performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry MassLynx(TM) MassFragment. Improving conventional techniques, integrated offers sensitivity increased analytical speed using columns packed sub-2 μm particles (1.7 μm), which allows a faster separation to be achieved. Through...
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