A5085955550- Atmospheric chemistry and aerosols
- Air Quality and Health Impacts
- Air Quality Monitoring and Forecasting
- Catalytic Processes in Materials Science
- Atmospheric Ozone and Climate
- Galectins and Cancer Biology
- Ferroptosis and cancer prognosis
- Vehicle emissions and performance
- RNA modifications and cancer
- Glycosylation and Glycoproteins Research
- Cancer-related molecular mechanisms research
- Catalysis and Oxidation Reactions
- Atmospheric aerosols and clouds
- Caveolin-1 and cellular processes
- Helicobacter pylori-related gastroenterology studies
- Cancer-related gene regulation
- Pancreatic and Hepatic Oncology Research
- Advanced Chemical Physics Studies
- Chemical Synthesis and Analysis
- Problem and Project Based Learning
- Ammonia Synthesis and Nitrogen Reduction
- Bone Metabolism and Diseases
- Carbon and Quantum Dots Applications
- Proteoglycans and glycosaminoglycans research
- Water Treatment and Disinfection
State Key Joint Laboratory of Environment Simulation and Pollution Control
2016-2024
Research Center for Eco-Environmental Sciences
2016-2024
Chinese Academy of Sciences
2016-2024
Tongji University
2012-2024
Tongji Hospital
2012-2024
Peking University
2021-2024
University of Chinese Academy of Sciences
2016-2022
Zhangjiakou Academy of Agricultural Sciences
2010
Molecular analyses help to investigate the key precursors and chemical processes of secondary organic aerosol (SOA) formation. We obtained sources molecular compositions in PM2.5 winter Beijing by online offline mass spectrometer measurements. Photochemical aqueous processing were both involved producing SOA during haze events. Aromatics, isoprene, long-chain alkanes or alkenes, carbonyls such as glyoxal methylglyoxal all important precursors. The enhanced formation severe event was...
Abstract Secondary organic aerosol (SOA) plays a significant role in contributing to atmospheric fine particles, as well global air quality and climate. However, the current understanding of formation SOA its simulation is still highly uncertain due complexity precursor VOCs. In our study, different mixed VOC scenarios was investigated using 30 m 3 indoor smog chamber. By comparing individual scenarios, it found that yield from anthropogenic VOCs (AVOCs) can be positively (+83.9%) affected...
China is facing dual pressures to reduce both PM2.5 and O3 pollution, the crucial precursors of which are NOx VOCs. In our study, role in secondary organic aerosol (SOA, important constituent PM2.5) formation was examined 30 m3 indoor smog chamber. As revealed present level can obviously affect OH concentration volatility distribution gas-phase oxidation products thus SOA formation. Reducing NOx-sensitive regime inhibit (by 42%), resulting reduction capacity, suppresses 45%) by inhibiting O-...
Abstract Different adverse health effects of submicron (PM 1 ) and fine particles 2.5 may be attributed to their chemical differences, requiring a better understanding size‐resolved composition. Herein, extensive online measurements were conducted across seasons in Beijing by two aerosol mass spectrometers, one which alternately sampled PM . Source apportionment organic (OA) indicated that traffic‐ cooking‐related OA together accounted for ∼20%−30% the , showing insignificant seasonal...
Abstract. Although the anthropogenic emissions of SO2 have decreased significantly in China, decrease SO42- PM2.5 is much smaller than that SO2. This implies an enhanced formation rate ambient air, and mechanism still under debate. work investigated particulate sulfate based on statistical analysis long-term observations Shijiazhuang Beijing supported with flow tube experiments. Our main finding was sulfur oxidation ratio (SOR) exponentially correlated RH (SOR = 0.15+0.0032×exp(RH/16.2))...
Abstract. It has been recognized that carbon nanomaterials and soot particles are toxic for human health, but the influence of functionalization on their toxicity as well evolution due to chemical aging in atmosphere is still controversial. In current study, oxidation potential measured by dithiothreitol (DTT) decay rate cytotoxicity murine macrophage cells different functionalized were investigated understand role toxicities. The DTT rates special black 4A (SB4A), graphene, graphene oxide,...
Vehicular evaporative emissions make an increasing contribution to anthropogenic sources of volatile organic compounds (VOCs), thus contributing secondary aerosol (SOA) formation. However, few studies have been conducted on SOA formation from vehicle VOCs under complex pollution conditions with the coexistence NOx, SO2, and NH3. In this study, synergistic effects SO2 NH3 gasoline NOx were examined using a 30 m3 smog chamber aid series mass spectrometers. Compared systems involving or alone,...
Abstract. Oxygenated organic molecules (OOMs) produced by the oxidation of aromatic compounds are key components secondary aerosol (SOA) in urban environments. The steric effects substitutions and rings role reaction pathways altering OOM distributions remain unclear because lack systematic multi-precursor study over a wide range OH exposure. In this study, we conducted flow-tube experiments used nitrate adduct time-of-flight chemical ionization mass spectrometer (NO3--TOF-CIMS) to measure...
HONO acts as a major OH source, playing vital role in secondary pollutant formation to deteriorate regional air quality. Strong unknown sources of daytime have been widely reported, which significantly limit our understanding radical cycling and atmospheric oxidation capacity. Here, we identify potential source originating from photoexcited phenyl organic nitrates formed during the photoreaction aromatics NOx. Significant (1.56–4.52 ppb) production is observed different kinds with NOx...
Fine particulate matter (PM
Objective: To investigate the effects of bone morphogenetic protein-2 (BMP-2) on proliferation, differentiation and apoptosis normal human gastric mucosal cells cancer cells.Methods: Poorly differentiated BGC823 cells, moderately epithelial GES-1 were independently treated with recombinant BMP-2 or its inhibitor Noggin.MTT assay was performed to detect flow cytometry done measure cell cycle immunohistochemistry carried out determine expression cyclin-dependent kinase 4 (CDK4).Results:...
Alkylamines contribute to both new particle formation and brown carbon. The toxicity of particle-phase amines is great concern in the atmospheric chemistry community. Degradation particulate may lead secondary products phase, which are associated with changes adverse health impacts aerosols. In this study, O3 oxidation trimethylamine (TMA) formed via heterogeneous uptake TMA by (NH4)2SO4, NH4HSO4, NH4NO3 NH4Cl, was investigated situ attenuated total reflection Fourier transform infrared...
N-acetylglucosaminyltransferase V (GnT-V) is an enzyme that catalyzes β1-6 branching of N-acetylglucosamine on asparagine (N)-linked oligosaccharides (N-glycan) cell proteins and the dysfunction which a common feature various carcinomas. Nevertheless, role GnT-V remains controversial. Therefore, clinical implication expression may differ in each cancer type. The status patients with gastric has not been studied extensively. In present study, we examined specimen both at protein mRNA levels....
Trefoil Factor Family (TFF) plays an essential role in the intestinal epithelial restitution, but relationship between TFF1 and gastric cancer (GC) is still unclear. The present study aimed to determine of repairing mucosa pathogenesis GC. expression different mucosas was measured with immunohistochemistry. Then, siRNA targeting or plasmids expressing gene were transfected into BGC823 cells, SGC7901 cells GES-1 cells. cell proliferation detected MTT assay apoptosis cycle by flow cytometry....
Volatile organic compounds (VOCs) are important precursors of O3 and secondary aerosols (SOAs). In order to fully understand the impacts VOCs from motor vehicles on urban air quality, current state-of-the-art research results source apportionment systematically introduced. The contribution pollutants in China is further discussed. It was found that vehicle exhaust largest atmospheric VOCs, average ratio up 36.8%, wherein motorcycles light gasoline main emission sources. showed play an role...
Secondary organic aerosol (SOA) is a significant component of atmospheric fine particulate matter (PM2.5), and their physicochemical properties can be significantly changed in the aging process. In this study, we used combination consisting smog chamber (SC) oxidation flow reactor (OFR) to investigate continuous process gas-phase intermediates SOA formed from photooxidation toluene, typical aromatic hydrocarbon. Our results showed that as OH exposure increased 2.6 × 1011 6.3 molecules cm-3 s...