- Advanced X-ray and CT Imaging
- Medical Imaging Techniques and Applications
- Digital Radiography and Breast Imaging
- Radiology practices and education
- Radiation Dose and Imaging
- Diversity and Career in Medicine
- Neuroendocrine Tumor Research Advances
- Neuroblastoma Research and Treatments
- Lung Cancer Research Studies
- Global Health Workforce Issues
- Epilepsy research and treatment
- Advanced Radiotherapy Techniques
- Medical Imaging and Pathology Studies
- Neonatal and fetal brain pathology
- Vascular Procedures and Complications
- Ultrasound in Clinical Applications
- Multiple Sclerosis Research Studies
- Pleural and Pulmonary Diseases
- HIV-related health complications and treatments
- Medical Malpractice and Liability Issues
- Medical Education and Admissions
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gallbladder and Bile Duct Disorders
- Cardiac Imaging and Diagnostics
- Biliary and Gastrointestinal Fistulas
Bradford Teaching Hospitals NHS Foundation Trust
2025
VA Tennessee Valley Healthcare System
2019-2024
Vanderbilt University Medical Center
2016-2024
The University of Texas MD Anderson Cancer Center
2022
Vanderbilt University
2005-2019
Medical University of South Carolina
2009-2016
Duke University
2003-2005
Duke University Hospital
2004-2005
Duke Medical Center
2003-2005
<h3>Background</h3> Natalizumab (NTZ), a monoclonal antibody to human α<sub>4</sub>β<sub>1</sub>/β<sub>7</sub> integrin, is an effective therapy for multiple sclerosis (MS), albeit associated with progressive multifocal leukoencephalopathy (PML). Clinicians have been extending the dose of infusions hypothesis reducing PML risk. The aim study evaluate clinical consequences NTZ frequency infusion up 8 weeks 5 days. <h3>Methods</h3> A retrospective chart review in 9 MS centres was performed...
The purpose of this simulation study was to evaluate the feasibility, benefits, and potential operating parameters a quasi‐monochromatic beam from tungsten‐target x‐ray source yielding projection images. application is intended for newly developed cone computed mammotomography (CmT) an uncompressed breast. value near monochromatic fully 3D CmT expected improved ability separate tissues with very small differences in attenuation coefficients. yield enhanced tomographic image quality along low...
Radiopharmaceuticals targeting cell surface expression of somatostatin receptors (SSTRs) are particularly useful in the evaluation neuroendocrine tumors. Gallium-68 DOTA-Tyr-octreotatate (Ga-DOTATATE) primarily binds to SSTR type 2 receptors. Ga DOTATATE PET/CT is proven have high impact on management patients compared traditional anatomical imaging as well provides additional information over that conventional nuclear medicine studies (indium-III DTPA-octreotide). It can result change...
Summary Introduction Arterial trauma is a rare, but potentially life‐threatening complication of central venous catheter insertion, with limited evidence to guide its prevention and management. We aimed identify incidents from two national databases incident reports better characterise this consequences. Methods extracted analysed the National Reporting Learning System Strategic Executive Information over 10‐year period, including involving arterial insertion dilator or catheter. puncture by...
<h3>Importance</h3> Despite the benefit of peptide receptor radionuclide therapy (PRRT) for patients with well-differentiated neuroendocrine tumors (WD NETs), no clinical metric to anticipate from individual has been previously defined. <h3>Objective</h3> To assess whether prognostic ability score (CS) could be validated in an external cohort WD NETs. <h3>Design, Setting, and Participants</h3> This multicenter study's analysis included NETs who were under consideration lutetium-177...
Radiology remains one of the least diverse fields in medicine. With increasing understanding benefits workforce diversity on health care outcomes, radiology society leadership and radiologists are engaging necessary efforts to improve diversity, equity, inclusion. To date, much initiatives have focused pipeline development recruitment strategies. Literature from organizational psychologists, human resources business strategists suggest that incorporation inclusion could overcome some...
Hewett, Lee J.; Bradshaw, Marques L.; Gordon, Leonie Rockey, Don C. Author Information
We evaluate the feasibility, benefits, and operating parameters of a quasimonochromatic beam for newly developed x-ray cone computed mammotomography application. The value near monochromatic source fully 3D dedicated is expected improved ability to separate tissues with very small differences in attenuation coefficients while maintaining dose levels at or below that existing dual view mammography. In previous studies, simulations range tungsten tube potentials, K-edge filter materials,...
The aim of this prospective study is to investigate the diagnostic performance integrated positron emission tomography (PET) /dual-energy computed (DECT) imaging in determining thoracic nodal status patients with small-cell lung cancer (SCLC) or non-small-cell (NSCLC) and resulting impact on target volume delineation for radiation therapy planning. This a single-center including approximately 50 suspected confirmed SCLC NSCLC, referred PET study. All will be examined clinical PET/DECT...
In an effort to image smaller breast lesions, two compact gamma cameras with different intrinsic NaI(Tl) pixel sizes are evaluated for use in the application specific emission tomography (ASET) system dedicated mammotomographic imaging. Comparison measurements were made scintillator arrays having 1.3/spl times/1.3/spl times/6 mm/sup 3/ or 2.0/spl times/2.0/spl elements on exactly same set of PMTs, electronics and control/processing hardware. Uniformity, sensitivity energy resolution assessed...
We developed a clinical score (CS) at Vanderbilt Ingram Cancer Center (VICC) that we hoped would predict outcomes for patients with progressive well-differentiated neuroendocrine tumors (NETs) receiving therapy Lutetium-177 (177Lu)-DOTATATE. Patients under consideration 177Lu-DOTATATE between March 1, 2016 and 17, 2020 VICC were assigned CS prospectively. The included 5 categories: available treatments tumor type outside of 177Lu-DOTATATE, prior systemic treatments, patient symptoms, burden...
The purpose of this study was to determine the optimum beam quality in terms kVp and filtration for a tungsten-target x-ray source newly developed cone computed mammotomography application. optimized is expected yield enhanced image along with low dose, equal or less than that dual view mammography. X-ray spectra were computer generated range tube potentials, filter materials, breast thicknesses. uncompressed modeled from 8, 12, 16 cm thick tissue, lesions as 0.5 striated muscle mass 0.02...
Abstract Background In the general population, it is established that adipose tissue depots pose various risks for cardiometabolic diseases. The interaction among obesity, HIV, and antiretroviral treatment promotes even greater risk persons with HIV (PWH). As obesity a heterogeneous condition, determining specific phenotypes present their characteristics critical to personalize care in PWH. Methods Visceral, sarcopenic, myosteatotic, hepatosteatotic, metabolically healthy were determined by...