A5081921175- Pain Management and Placebo Effect
- Connective tissue disorders research
- Botulinum Toxin and Related Neurological Disorders
- Pain Mechanisms and Treatments
- Acupuncture Treatment Research Studies
- Complementary and Alternative Medicine Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Health, Medicine and Society
- Clinical practice guidelines implementation
- Axon Guidance and Neuronal Signaling
- Alcoholism and Thiamine Deficiency
- Neurological and metabolic disorders
- Angiogenesis and VEGF in Cancer
- Diet and metabolism studies
- Innovations in Medical Education
- Genetic Neurodegenerative Diseases
- Healthcare and Venom Research
- EEG and Brain-Computer Interfaces
- Neonatal and fetal brain pathology
- Antibiotics Pharmacokinetics and Efficacy
- Infant Health and Development
- Empathy and Medical Education
- Clusterin in disease pathology
- Myofascial pain diagnosis and treatment
- thermodynamics and calorimetric analyses
University Hospital of Lausanne
2022-2025
University of Lausanne
2018-2024
The Sense Innovation and Research Center
2024
National Center for Complementary and Integrative Health
2022-2024
Inserm
2014-2020
Université de Strasbourg
2014-2020
Hospital Universitario Infanta Leonor
2008
The neuropilin-plexin receptor complex regulates tumor cell migration and proliferation thus is an interesting therapeutic target. High expression of neuropilin-1 indeed associated with a bad prognosis in glioma patients. Q-RTPCR tissue-array analyses showed here that Plexin-A1 highly expressed glioblastoma the highest level correlates worse survival We next identified developmental tumor-associated pro-angiogenic role Plexin-A1. Hence, by using molecular simulations two-hybrid like assay...
// Alexia Arpel 1, 2 , Coralie Gamper 1 Caroline Spenlé Aurore Fernandez Laurent Jacob Nadège Baumlin Patrice Laquerriere Gertraud Orend Gérard Crémel Dominique Bagnard INSERM U 1109, MN3T Laboratory, Labex Medalis, Strasbourg University, Strasbourg, France CNRS UMR 7178, Institut Pluridisciplinaire Hubert Curien, Correspondence to: Bagnard, email: bagnard@unistra.fr Keywords: neuropilin-1, breast cancer, metastasis, treatment, peptide Received: September 28, 2015 Accepted: May 2016...
Exploring psychophysiological changes during hypnosis can help to better understand the nature and extent of hypnotic phenomenon by characterizing its influence on autonomic nervous system (ANS), in addition central brain effects. Hypnosis is thought induce a relaxation response, yet studies using objective measures alongside protocols show various results. We review this literature clarify effects indices ANS activity more specifically stress/relaxation such as heart rate variability...
Side effects are frequent in pharmacological pain management, potentially preceding analgesia and limiting drug tolerability. Discussing side is part of informed consent, yet can favor nocebo effects. This study aimed to test whether a positive suggestion regarding effects, which could act as reminders the medication having been absorbed, might clinical interaction model. Sixty-six healthy males participated "to validate pupillometry an objective measure analgesia". Participants were...
Abstract Background The hypermobile Ehlers–Danlos syndrome (hEDS) and hypermobility spectrum disorders (HSD) are connective tissue characterized by generalized joint hypermobility, associated with chronic pain several symptoms, such as fatigue, dysautonomia, well psychiatric co‐morbidities. Clinical observations of unusual manifestations during systematic sensory testing raised the question a possible co‐existence functional neurological disorder (FND). Hence, this study aimed to assess...
Hypnosis can be a beneficial complementary anesthesia technique for variety of surgical procedures. Despite favorable scientific evidence, hypnosis is still rarely used in the operating room. Obstacles to implementation could lack interest or training, misconceptions, as well limited knowledge amongst anesthesiology teams. Hence, this study aimed assess interest, beliefs, and about room staff.A questionnaire with 21-items, based on prior survey, was set up an online platform. The medical...
The presence of stromal cells in tumors is altering the significance molecular profiling when using standard methods gene expression quantification. We developed a novel normalization method to rank target tumor samples by comparisons with reference representing different cell types found tumor. score for each obtained after normalization, aimed be predictive targeted therapies efficiency. performed this qPCR analysis on human colorectal cancers demonstrate importance obtain accurate data...
Chronic heavy alcohol use is known to cause neurological complications such as peripheral neuropathy. Concerning the pathophysiology, few sural nerve and skin biopsy studies showed that small fibers might be selectively vulnerable degeneration in alcohol-related Pain has rarely been properly evaluated this pathology. The present study aims at assessing pain intensity, potential neuropathic characteristics well functionality of both large sensitive fibers.In observational study, 27...
To illustrate the news of 2023 in integrative medicine, authors summarized four particularly relevant studies. The first highlights one foundational principles describing importance respecting patient preference choice a therapeutic approach, promoting their «empowerment». second article proposes methodological recommendations to improve scientific value studies assessing efficacy and mechanisms non-pharmacological approaches. Finally, last two articles are randomized designed either...
Despite chronic primary pain being recognized as a disease in the 11th revision of International Classification Diseases (ICD-11), individuals suffering from it are still too frequently met with certain skepticism. This skepticism can detrimentally affect their healthcare journey, social life, and economic stability. article outlines part legal evolution regarding recognition well current insurance-related provisions Switzerland. With thorough understanding this system, physicians reduce...
Maladaptive stress responses may exacerbate chronic widespread pain (CWP) and deserve further investigations. Yet, existing paradigms lack relevance for individuals with this condition. Hence, we developed the Social Benefits Stress Test (SBST), adapted from Trier Test. Instead of a job interview, patients task is to justify their inability work in front simulated medical expert social insurances. Forty women type CWP: hypermobile Ehlers-Danlos syndrome hypermobility spectrum disorders were...
Médecine intégrative : ce qui a changé en 2022En termes de nouveautés 2022, nous présentons premier lieu un article scientifique traitant la pleine conscience une méta-analyse montre des effets tant préventifs que thérapeutiques pour population pédiatrique.Le deuxième présenté traite l'acupuncture dans contexte obstétrical, démontrant son efficacité sur douleur postcésarienne et capacité fonctionnelle, améliorant mobilisation précoce.Ces deux approches bénéficient donc d'un niveau preuve...