A5029470750- Mycotoxins in Agriculture and Food
- Plant Pathogens and Fungal Diseases
- Vibrio bacteria research studies
- Fungal Biology and Applications
- Plant-Microbe Interactions and Immunity
- Wheat and Barley Genetics and Pathology
- Biochemical and Structural Characterization
- Salmonella and Campylobacter epidemiology
- Antibiotic Resistance in Bacteria
- Malaria Research and Control
- CRISPR and Genetic Engineering
Queen's University
2020-2024
Fusarium Head Blight of wheat, caused by the filamentous fungus graminearum, leads to devastating global food shortages and economic losses. While many studies have addressed responses both wheat F. graminearum during their interaction, possibility fungal chemotropic sensing enabling pathogenicity remains unexplored. Based on recent findings linking pheromone-sensing G-protein-coupled receptor Ste2 host-directed chemotropism in oxysporum, we investigated role its downstream signaling...
Introduction The fungal G protein-coupled receptors Ste2 and Ste3 are vital in mediating directional hyphal growth of the agricultural pathogen Fusarium graminearum towards wheat plants. This chemotropism is induced by a catalytic product peroxidases secreted wheat. Currently, identity this product, substrate it generated from, not known. Methods results We provide evidence that peroxidase derived from F. conidia report simple method to extract purify Fg Ste2-activating ligand for analyses...
Fungal hyphal chemotropism has been shown to be a major contributor host-pathogen interactions. Previous studies on Fusarium species have highlighted the involvement of Ste2 G-protein-coupled receptor (GPCR) in mediating polarized growth toward host-released peroxidase. Here, role opposite mating type GPCR, Ste3, is characterized with respect graminearum and pathogenicity.