A5048133955- Functional Brain Connectivity Studies
- Schizophrenia research and treatment
- Psychosomatic Disorders and Their Treatments
- Advanced Neuroimaging Techniques and Applications
- Tryptophan and brain disorders
- Genetic Mapping and Diversity in Plants and Animals
- Attention Deficit Hyperactivity Disorder
- Mental Health and Psychiatry
- Vitamin D Research Studies
- Bipolar Disorder and Treatment
- Neural and Behavioral Psychology Studies
- Personality Disorders and Psychopathology
- Identity, Memory, and Therapy
- Genetic Associations and Epidemiology
- Obsessive-Compulsive Spectrum Disorders
- Bioinformatics and Genomic Networks
- Congenital heart defects research
- Cardiac electrophysiology and arrhythmias
- Suicide and Self-Harm Studies
- Neurotransmitter Receptor Influence on Behavior
- Down syndrome and intellectual disability research
- Diet and metabolism studies
- Forensic and Genetic Research
- Diabetes Management and Research
- Gastrointestinal motility and disorders
Hospital Universitario San Rafael
2006-2024
Hospital Mare de Déu de la Mercè
2018-2022
Fidmag Sisters Hospitallers
2015-2021
Instituto de Salud Carlos III
2021
Centro de Investigación Biomédica en Red de Salud Mental
2017-2021
Universitat Autònoma de Barcelona
2006-2019
Hospital General de Catalunya
2011
Rafael Advanced Defense Systems (Israel)
2007-2009
Objective: Functional imaging studies have found reduced frontal activity, mainly in dorso/ventro-lateral regions and task-related de-activation of the default mode network childhood ADHD. Adult are fewer inconclusive. We aimed to investigate potential neural bases executive function ADHD adults, examining brain activity during N-back task performance, explore corrective effects long-term methylphenidate treatment. Method: recruited a large adult ADHD-combined sample matched control group...
An alteration in self/other differentiation has been proposed as a basis for several symptoms schizophrenia, including delusions of reference and social functioning deficits. Dysfunction the right temporo-parietal junction (TPJ), region linked with cognition, this alteration. However, imaging studies self- other-processing schizophrenia have shown, so far, inconsistent results. Patients healthy controls underwent fMRI scanning while performing task three conditions: self-reflection,...
Abstract Objective A post‐hoc analysis of the data from a randomised clinical trial involving prescription antipsychotic treatment to never treated first‐onset psychotic patients was used compare weight change after 6‐week olanzapine (standard tablets vs. orally disintegrating formulation). Method In subgroup 38 olanzapine, standard were non‐randomly and consecutively prescribed first 19 patients, with formulation being following patients. Results After significant higher increase in noted...
Few studies have looked at the prevalence of substance use disorders (SUD) in people with intellectual disability (ID). The results range between 1% and 6.4% go up to 20% ID psychiatric disorders, probably underestimating real due several limitations these studies. confers risk for development SUD, which turn will involve negative psychosocial clinical consequences. We aimed study SUD a sample patients admitted brief hospitalisation unit, describing them by type severity analysing their...
The brain functional correlates of autobiographical recall are well established, but have been little studied in schizophrenia. Additionally, memory is one a small number cognitive tasks that activates rather than de-activates the default mode network, which has found to be dysfunctional this disorder.Twenty-seven schizophrenic patients and 30 healthy controls underwent magnetic resonance imaging while viewing cue words evoked memories. Control conditions included both non-memory-evoking...
Abstract Schizophrenia may represent a trade-off in the evolution of human-specific ontogenetic mechanisms that guide neurodevelopment. Human Accelerated Regions (HARs) are evolutionary markers functioning as neurodevelopmental transcription enhancers have been associated with brain configuration, neural information processing, and schizophrenia risk. Here, we investigated influence HARs’ polygenic load on neuroanatomical measures through case-control approach (128 patients 115 controls). To...
Abstract Vitamin D deficiency has been linked with schizophrenia. We aimed to determine whether patients a first episode of psychosis (FEP) had lower vitamin levels compared controls considering their final diagnosis. conducted cross-sectional study determining 25-hydroxyvitamin blood levels. 25-Hydroxyvitamin were considered optimum at 20 ng/mL or greater. A group 45 adult FEP and 22 healthy matched for age recruited. The patient was subdivided in two diagnosis groups (schizophrenia versus...
Objective: The study aimed to establish clinical predictors of non‐affective acute remitting psychosis (NARP) and assess whether these patients showed a distinct serotonergic profile. Method: First‐episode never treated psychotic diagnosed paranoid schizophrenia ( n = 35; 21 men 14 women) or NARP 28; 15 13 were included. Results: significantly lower negative symptomatology, better premorbid adjustment, shorter duration untreated psychosis, more depressive symptomatology number 5‐HT2A...
Previous studies have shown that the gene encoding adhesion G protein-coupled receptor L3 (ADGRL3; formerly latrophilin 3, LPHN3) is associated with Attention-Deficit/Hyperactivity Disorder (ADHD). Conversely, no investigated anatomical or functional brain substrates of ADGRL3 risk variants. We examined here whether individuals different haplotypes, including both patients ADHD and healthy controls, showed differences in anatomy function. recruited genotyped adult combined type controls to...
<h3>Background</h3> Studies suggest a neuroprotective role for vitamin D. Its deficit has been linked with various psychiatric disorders such as schizophrenia (1). Increase in the prevalence of associated high latitudes, winter/spring births, migration, urbanicity and cold climates (2,3). Vitamin D deficiency could be an important environmental risk factor, linking all previously exposed. <h3>Objectives</h3> We aimed to determine whether patients first psychotic episode had low levels...
ABSTRACT Schizophrenia (SZ) is hypothesised to represent a costly trade-off in the evolution of neurodevelopmental ontogenetic mechanisms associated with human-specific cognitive capacities. Human Accelerated Regions (HARs) are evolutionary conserved genomic regions that have accumulated sequence changes. These markers function as transcription enhancers and been brain’s cortical expansion connectivity, processing neural information, risk for SZ. We sought investigate whether HARs’ polygenic...
In order to better understand individual vulnerabilities bipolar I disorder, our study evaluates differences in Behavioral Activation and Inhibition Systems as possible markers of disorder. We evaluated BAS BIS functioning 39 euthymic patients 38 controls. Patients showed higher scores on the scale while weren't detected scale. Eighteen months after initial assessment, were re-grouped according presence type new affective episodes. Those relapsing with a depressive episode lower than...