A5077428355- Colorectal Cancer Screening and Detection
- Genetic factors in colorectal cancer
- Multiple and Secondary Primary Cancers
- Global Cancer Incidence and Screening
- Pancreatic and Hepatic Oncology Research
- Gastric Cancer Management and Outcomes
Tulane University
2019-2020
<h3>Importance</h3> Early-onset colorectal cancer incidence rates among patients aged 45 to 49 years have been considered much lower compared with the 50 54 years, prompting debate about earlier screening benefits at years. However, observed in Surveillance, Epidemiology, and End Results (SEER) registries may underestimate case burdens those younger than older because average-risk is generally not performed detect preclinical cases of cancer. Finding steep increases invasive stage (beyond...
Background: Early-onset colorectal cancer (EOCRC) incidence rates (IRs) are rising, according to previous registry analyses. However, analysis of histologic subtypes, including adenocarcinoma (the focus CRC screening and diagnostic testing) carcinoid tumors (which classified as "colorectal cancer" in SEER [Surveillance, Epidemiology, End Results] databases but have a distinct pathogenesis managed differently from adenocarcinoma), has not been reported. Objective: To assess EOCRC IRs changes...
Although early-onset colorectal cancer (EOCRC) incidence rates (IRs) are increasing, geographic and intra-racial IR disparities not well defined.2000-2015 Surveillance, Epidemiology, End Results (SEER) program CRC Analysis (170,434 cases) was performed from ages 30 to 60 in four US regions, 18 individual registries, metropolitan nonmetropolitan locations stratified by race. Analyses were conducted 1-year 5-year age increments.Wide regional EOCRC variations exist: For example, 45 IRs the...
INTRODUCTION: SEER 9 analysis has revealed rising incidence of early-onset colorectal cancer (EOCRC) in 40–49 year-olds and within 50–54 year-olds. We seek to analyze 18 EOCRC rates as this represents a greater percentage the U.S. population compared (28% vs. 9%). Furthermore, given evidence carcinoid (CN) are increasing these tumors may potentially be broadly categorized “colorectal cancer,” we aimed sub-stratify by histology. METHODS: Age-specific CRC, colon only rectal from (2000–2016)...
INTRODUCTION: SEER 9 analysis has revealed rising early-onset colorectal cancer (EOCRC) incidence. We seek to analyze 18 EOCRC rates as this represents a greater percentage of the U.S. population compared (28% vs. 9%). Furthermore, given evidence carcinoid (CN) are increasing and these tumors may potentially be broadly categorized “colorectal cancer,” we aimed substratify by histology. METHODS: Age-specific CRC, colon only rectal incidence from (2000–2016) were generated in yearly intervals...
INTRODUCTION: Prior study by our group revealed marked geographic disparities in early-onset colorectal cancer (EOCRC) incidence rates (IR) (Abualkhair et al. abstract #984 DDW 2019). Although it is established CRC IRs African Americans are higher than whites, there paucity of data on EOCRC within both white and American populations. Hence, we seek to explore the role race may play IR differences between U.S. regions individual registries. METHODS: 2000–2015 SEER 18 Analysis (170,434 cases)...