Guodong Wang

ORCID: 0000-0001-9917-0656
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About
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Research Areas
  • Plant biochemistry and biosynthesis
  • Plant Gene Expression Analysis
  • Plant Stress Responses and Tolerance
  • Photosynthetic Processes and Mechanisms
  • Plant Molecular Biology Research
  • Natural product bioactivities and synthesis
  • Plant nutrient uptake and metabolism
  • Organ Transplantation Techniques and Outcomes
  • Soybean genetics and cultivation
  • Plant Reproductive Biology
  • Biochemical and biochemical processes
  • Microbial Natural Products and Biosynthesis
  • Hops Chemistry and Applications
  • Plant-Microbe Interactions and Immunity
  • Heat shock proteins research
  • Mitochondrial Function and Pathology
  • Plant responses to water stress
  • Light effects on plants
  • Legume Nitrogen Fixing Symbiosis
  • Transplantation: Methods and Outcomes
  • Lipid metabolism and biosynthesis
  • Metabolism and Genetic Disorders
  • Physiological and biochemical adaptations
  • Fermentation and Sensory Analysis
  • Urban Green Space and Health

State Key Laboratory of Plant Genomics
2016-2025

Institute of Genetics and Developmental Biology
2016-2025

Chinese Academy of Sciences
2016-2025

Ministry of Agriculture and Rural Affairs
2017-2025

Kailuan General Hospital
2020-2025

Northeast Institute of Geography and Agroecology
2013-2025

Shanghai Changzheng Hospital
2023-2025

Jimei University
2010-2025

Xinxiang Medical University
2024-2025

Shaanxi Normal University
2016-2024

Soybean (Glycine max [L.] Merr.) is one of the most important oil and protein crops. Ever-increasing soybean consumption necessitates improvement varieties for more efficient production. However, both correlations among different traits genetic interactions genes that affect a single trait pose challenge to breeding. To understand networks underlying phenotypic correlations, we collected 809 accessions worldwide phenotyped them two years at three locations 84 agronomic traits. Genome-wide...

10.1186/s13059-017-1289-9 article EN cc-by Genome biology 2017-08-24

The transition from the juvenile to adult phase in plants is controlled by diverse exogenous and endogenous cues such as age, day length, light, nutrients, temperature. Previous studies have shown that gradual decline microRNA156 (miR156) with age promotes expression of traits. However, how temporally regulates abundance miR156 poorly understood. We show here responds sugar. Sugar represses at both transcriptional level post-transcriptional through degradation primary transcripts....

10.7554/elife.00269 article EN cc-by eLife 2013-03-26

Abstract Receptor-like proteins (RLPs) are cell surface receptors that typically consist of an extracellular leucine-rich repeat domain, a transmembrane and short cytoplasmatic tail. In several plant species, RLPs have been found to play role in disease resistance, such as the tomato (Solanum lycopersicum) Cf Ve apple (Malus domestica) HcrVf2 protein mediate resistance against fungal pathogens Cladosporium fulvum, Verticillium spp., Venturia inaequalis, respectively. addition, development;...

10.1104/pp.108.119487 article EN cc-by PLANT PHYSIOLOGY 2008-04-23

Thellungiella salsuginea, a close relative of Arabidopsis , represents an extremophile model for abiotic stress tolerance studies. We present the draft sequence T. salsuginea genome, assembled based on ∼134-fold coverage to seven chromosomes with coding capacity at least 28,457 genes. This genome provides resources and evidence about nature defense mechanisms constituting genetic basis underlying plant tolerance. Comparative genomics experimental analyses identified genes related cation...

10.1073/pnas.1209954109 article EN Proceedings of the National Academy of Sciences 2012-07-09

Abstract The seed oil content in oilseed crops is a major selection trait to breeders. In Arabidopsis (Arabidopsis thaliana), LEAFY COTYLEDON1 (LEC1) and LEC1-LIKE (L1L) are key regulators of fatty acid biosynthesis. Overexpression AtLEC1 its orthologs canola (Brassica napus), BnLEC1 BnL1L, causes an increased level transgenic plants, which, however, also show severe developmental abnormalities. Here, we use truncated napin A promoters, which retain the seed-specific expression pattern but...

10.1104/pp.111.175000 article EN cc-by PLANT PHYSIOLOGY 2011-05-11

Significance The phytohormone indole-3-acetic acid (IAA) plays a vital role in plant growth and development. IAA can be synthesized through the precursor tryptophan (Trp), known as Trp-dependent biosynthetic pathway. However, may also proposed Trp-independent Although biosynthesis was hypothesized 20 years ago, it remains mystery. In this paper, we provide compelling evidence that cytosol-localized indole synthase (INS) initiates pathway spatial temporal expression of INS an important...

10.1073/pnas.1503998112 article EN Proceedings of the National Academy of Sciences 2015-03-23

Abstract The flavonoid xanthohumol is an important flavor substance in the brewing industry that has a wide variety of bioactivities. However, its unstable structure results low content beer. Microbial biosynthesis considered sustainable and economically viable alternative. Here, we harness yeast Saccharomyces cerevisiae for de novo from glucose by balancing three parallel biosynthetic pathways, prenyltransferase engineering, enhancing precursor supply, constructing enzyme fusion,...

10.1038/s41467-023-44654-5 article EN cc-by Nature Communications 2024-01-04

Abstract Hop (Humulus lupulus L. Cannabaceae) is an economically important crop for the brewing industry, where it used to impart flavor and aroma beer, has also drawn attention in recent years due its potential pharmaceutical applications. Essential oils (mono- sesquiterpenes), bitter acids (prenylated polyketides), prenylflavonoids are primary phytochemical components that account these traits, all accumulate at high concentrations glandular trichomes of hop cones. To understand molecular...

10.1104/pp.108.125187 article EN cc-by PLANT PHYSIOLOGY 2008-09-05

Background And Objective The investigation concerning the B7-H1 expression in colorectal cancer cells is at an early stage. It unclear whether may have diagnostic or prognostic value carcinoma. Additionally, how associated with clinical features of carcinoma not known. In order to investigate relationship between and cancer, we analyzed its effect specimens HCT116 cells. Methods Paraffin-embedded from 143 eligible patients were used CD274 by immunohistochemistry. We also examined itself be...

10.1371/journal.pone.0076012 article EN cc-by PLoS ONE 2013-10-04

Myrcene, which accounts for 30–50% of the essential oil in hop ( Humulus lupulus L.) trichomes, derives from geranyl diphosphate (GPP), common precursor monoterpenes. Full-length sequences heterodimeric GPP synthase small subunit (GPPS.SSU, belonging to SSU I subfamily) and large (LSU) cDNAs were mined a trichome cDNA library. The was inactive, whereas LSU produced GPP, farnesyl diphosphate, geranylgeranyl (GGPP) dimethylallyl isopentenyl vitro. Coexpression both subunits Escherichia coli...

10.1073/pnas.0904069106 article EN Proceedings of the National Academy of Sciences 2009-05-30

DnaJ proteins act as essential molecular chaperones in protein homeostasis and complex stabilization under stress conditions. The roles of a tomato (Lycopersicon esculentum) chloroplast-targeted (LeCDJ1), whose expression was upregulated by treatment at 4 42 °C, with high light, NaCl, polyethylene glycol, H2O2, were investigated here using sense antisense transgenic tomatoes. plants exhibited not only higher chlorophyll content, fresh weight net photosynthetic rate, but also lower...

10.1093/jxb/ert357 article EN Journal of Experimental Botany 2013-11-13

Programmed cell death (PCD) is a fundamental biological process. Deficiency in MOSAIC DEATH 1 (MOD1), plastid-localized enoyl-ACP reductase, leads to the accumulation of reactive oxygen species (ROS) and PCD, which can be suppressed by mitochondrial complex I mutations, indicating signal from chloroplasts mitochondria. However, this remains elucidated. In study, through cloning analyzing series mod1 suppressors, we reveal comprehensive organelle communication pathway that regulates...

10.1038/s41422-018-0024-8 article EN cc-by Cell Research 2018-03-14

Soybean (Glycine max) production is severely affected in unfavorable environments. Identification of the regulatory factors conferring stress tolerance would facilitate soybean breeding. In this study, through coexpression network analysis salt-tolerant wild soybeans, together with molecular and genetic approaches, we revealed a previously unidentified function class B heat shock factor, HSFB2b, salt response. We showed that HSFB2b improves promotion flavonoid accumulation by activating one...

10.1111/nph.16104 article EN New Phytologist 2019-08-10

Grain size is one of the most important determinants crop yield in cereals. Here, we identified a dominant mutant, big grain2 (bg2-D) from our enhancer-trapping population. Genetic analysis and SiteFinding PCR (polymerase chain reaction) revealed that BG2 encodes cytochrome P450, OsCYP78A13. Sequence search CYP78A13 has paralogue Length 3.2 (GL3.2, LOC_Os03g30420) rice with distinct expression patterns, transgenic plants harbouring either or GL3.2 showed both can promote grain growth....

10.1111/pce.12452 article EN Plant Cell & Environment 2014-09-25

Plant volatile organic compounds, which are generated in a tissue-specific manner, play important ecological roles the interactions between plants and their environments, including well-known functions of attracting pollinators protecting from herbivores/fungi attacks. However, to date, there have not been reports holistic profiling various tissues single plant species, even for model species. In this study, we qualitatively quantitatively analyzed 85 chemicals, 36 terpenes, 23 different...

10.1104/pp.16.01051 article EN PLANT PHYSIOLOGY 2016-07-25

NAC (NAM-ATAF1, 2-CUC2) family members play important roles in various environmental responses. Here, we cloned a full-length gene (954 bp) from Solanum lycopersicum (SlNAC1). This belonged to ATAF subfamily which included ATAF1 and ATAF2 of Arabidopsis thaliana. SlNAC1 expression was induced by chilling stress (4°C), heat (40°C), high salinity, osmotic mechanical wounding. transcripts were enhanced after application abscisic acid, methyl jasmonate, salicylic gibberellin, ethylene, viologen...

10.1111/ppl.12049 article EN Physiologia Plantarum 2013-03-14

The NAC transcription factor family participates in responses to various kinds of environmental stimuli plants. Responses genes abiotic stresses have been widely studied, but their functions response biotic stress are little reported plants, especially crops. In the present study, we examined a novel tomato ( Solanum lycopersicum ) protein SlNAC35 and resistance by using transgenic tobacco. Expression analysis found that expression was induced drought stress, salt bacterial pathogen,...

10.1111/ppl.12444 article EN Physiologia Plantarum 2016-03-19

The cascade reactions between NH2-functionalized enaminones and sulfonyl hydrazines have been developed for the synthesis of fully substituted pyrazoles. By making use hydrophilic primary amino group in enaminones, proceed well medium pure water presence molecular iodine, TBHP, NaHCO3 via C-H sulfonylation pyrazole annulation. cleavage C–N bond is confirmed by experiment using 15N-labeled enaminone.

10.1021/acs.joc.8b02897 article EN The Journal of Organic Chemistry 2019-02-04

Photosynthesis is one of the biological processes most sensitive to heat stress in plants. Carbon assimilation, which depends on ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco), major sites photosynthesis. In this study, roles a tomato (Solanum lycopersicum) chloroplast-targeted DnaJ protein (SlCDJ2) resisting using sense and antisense transgenic tomatoes were examined. SlCDJ2 was found be uniformly distributed thylakoids stroma chloroplasts. Under stress, plants exhibited higher...

10.1093/jxb/erv102 article EN Journal of Experimental Botany 2015-03-23

Abstract The conversion of lignocellulosic feedstocks to fermentable sugar for biofuel production is inefficient, and most strategies enhance efficiency directly target lignin biosynthesis, with associated negative growth impacts. Here we demonstrate, both laboratory- field-grown plants, that expression Pag-miR408 in poplar ( Populus alba × P. glandulosa ) significantly enhances saccharification, no requirement acid-pretreatment, while promoting plant growth. overexpression plants show...

10.1038/s41467-023-39930-3 article EN cc-by Nature Communications 2023-07-18
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