A5000208805- Leprosy Research and Treatment
- S100 Proteins and Annexins
- Peripheral Neuropathies and Disorders
- Cell Adhesion Molecules Research
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Diabetic Foot Ulcer Assessment and Management
- Pharmacological Effects and Toxicity Studies
- Chronic Lymphocytic Leukemia Research
- Erythrocyte Function and Pathophysiology
- Chemotherapy-related skin toxicity
- Pancreatic and Hepatic Oncology Research
- Foot and Ankle Surgery
- Orthopedic Surgery and Rehabilitation
- Gallbladder and Bile Duct Disorders
- Chronic Myeloid Leukemia Treatments
- Nail Diseases and Treatments
- Redox biology and oxidative stress
- Drug-Induced Hepatotoxicity and Protection
- Kawasaki Disease and Coronary Complications
- Pancreatitis Pathology and Treatment
- Medical Imaging Techniques and Applications
- Soft tissue tumors and treatment
- Nuclear Structure and Function
- Lower Extremity Biomechanics and Pathologies
Baylor College of Medicine
2024
University of Southern California
2018
The University of Texas MD Anderson Cancer Center
2018
Anesthesiology and Surgical Oncology Research Group
2018
Rice University
2018
Sorbonne Université
1992
Washington University in St. Louis
1985
United States Department of Veterans Affairs
1984
John Cochran VA Medical Center
1979
Saint Louis University Hospital
1976
Perioperative opioid use is associated with poor survival in patients esophageal squamous cell carcinoma. The most common histological type of cancer western countries adenocarcinoma. objective this study was to evaluate the association between intraoperative consumption and adenocarcinoma carcinoma esophagus.Records who had undergone surgery January 2000 2017 were reviewed. Comparisons made received high versus low doses opioids. Groups divided using recursive partitioning method....
A factor with chemotactic properties for neutrophils and mononuclear cells was extracted from the lysosomal fraction of both human rabbit that had been allowed to phagocytose monosodium urate crystals. The found be a glycoprotein mol wt 8,400 daltons. is heat labile has activity as well cells. Preincubation induced or complement activated plasma prevents cell migrating chemotactically when challenged either in chamber. induces release enzymes cytochalasin B treated neutrophils.
The crystal-induced chemotactic factor, a cell-derived chemoattractant for neutrophils, binds specifically to site on human neutrophils but not erythrocytes or lymphocytes, suggesting relationship between the presence of specific binding sites and ability be chemotactically activated. Scatchard analysis revealed an equilibrium dissociation constant at 37 degrees C 0.446 micrometer approximately equal 6.44 x 10(5) 125I-crystal-induced factor per cell. Binding was displaced by synthetic...
A 35-year-old female with borderline lepromatous (BL) leprosy who suffered from dapsone-induced erythroderma is reported. Sudden onset of gave rise to a temporary arrest the function nail matrix resultant Beau's lines. She rapidly recovered omission dapsone and therapy systemic corticosteroids topical emollient. In view potentially fatal hypersensitivity reaction, we suggest that any patient on multidrug for needs an urgent referral dermatologist if develops skin rash during first two months...
SummaryNiridazole, a nitrothiazole derivative, was tried in 32 patients with amebiasis. It is effective both amebic dysentery and hepatic amebiasis, gave cure rate of 77.7 72.7%, respectively. Electrocardiographic changes were observed 53.1% the patients. In eight who could be followed, EKG reverted to normal 2 4 weeks after end therapy. Confusional psychosis two patients, one whom died during treatment. The exact cause death not ascertained even autopsy.
Incubation of pulmonary alveolar macrophages (PAM) with the synthetic chemotactic tripeptide, N-formyl-methionyl-leucyl-phenylalanine (FMLP) results in deactivation PAM chemotaxis. The response to 10(-8) M FMLP was inhibited 85% after 30 min preincubation 10(-6) and 48% by FMLP. Only higher dose (10(-6) M) caused C5a (20%). Preincubation partially purified at a concentration 100 microliter/ml produced 32% inhibition In contrast, had no significant effect on superoxide generation, either...
The microfilament-disrupting agents cytochalasins A, B, and D were shown to impair the binding of chemotactic factors [3H]formylmethionylleucylphenylalanine 125 I-labeled crystal-induced factor their neutrophil receptor. Scatchard plot analysis revealed a decrease available sites in cytochalasin B-treated cells. Cytochalasin B showed same inhibitory profile on intact cells membrane-rich preparation, suggesting that effect was not dependent an microfilament apparatus. microtubule modifiers...
A 74-year-old man with a history of chronic lymphocytic leukemia (CLL) presented large salmon-colored patch lesions along the inferior fornix and superotemporal conjunctiva OS. The patient underwent an incisional biopsy lesions, which showed CLL areas B-cell lymphoma, consistent Richter transformation. Following medical radiation-based therapy these returned 3 months later inferomedial preseptal swelling in contralateral eye, proved to be recurrent/resistant low-grade posttreatment...
This paper investigates cash productivity as a signal for future stock performance, building on the cash-return framework of Faulkender and Wang (2006). Using financial market data from WRDS, we calculate returns proxy operational efficiency evaluate long-only strategy applied to Nasdaq-listed non-financial firms. Results show limited predictive power across broader Nasdaq universe but strong performance in handpicked portfolio, which achieves significant positive alpha after controlling...