A5054419435- RNA and protein synthesis mechanisms
- Viral Infections and Immunology Research
- RNA modifications and cancer
- Insect and Pesticide Research
- Insect and Arachnid Ecology and Behavior
- Plant and animal studies
- SARS-CoV-2 and COVID-19 Research
- Plant Virus Research Studies
Agriculture and Agri-Food Canada
2021-2025
Lethbridge Research and Development Centre
2025
University of Victoria
2020-2023
Monitoring the environment for pollution, pesticides, and pathogens is crucial protecting human, agriculture, overall ecosystem health. Diverse strategies ranging from physical sensors to sentinel species have been used environmental monitoring. The European honey bee, Apis mellifera, a globally managed pollinator that can serve as continuous biomonitoring species. During foraging, bees are exposed contaminants carry them their hives where they be detected quantified. Although individual...
Multiple coronaviruses including MERS-CoV causing Middle East Respiratory Syndrome, SARS-CoV SARS, and SARS-CoV-2 COVID-19, use a mechanism known as −1 programmed ribosomal frameshifting (−1 PRF) to replicate. possesses unique RNA pseudoknotted structure that stimulates PRF. Targeting PRF in impair viral replication can improve patients’ prognoses. Crucial developing these therapies is understanding the of pseudoknot. Our goal expand knowledge structural conformations. Following alignment...
ABSTRACT The gut microbiome of the European honey bee ( Apis mellifera ) is vital to its health, yet large-scale studies are scarce. We present metagenomic sequencing data from 180 samples collected near and far eight crops across Canada over 2 years. These sets will help address various biological environmental questions.
A bstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to the COVID-19 pandemic; a pandemic of scale that not been seen in modern era. Despite over 29 million reported cases and 900, 000 deaths worldwide as September 2020, herd immunity widespread vaccination efforts by many experts are expected be insufficient addressing this crisis for foreseeable future. Thus, there is an urgent need treatments can lessen effects SARS-CoV-2 patients who become seriously affected....
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to the COVID-19 pandemic. After over 160 million cases and 3.3 deaths worldwide as of May 2021, it is still unclear when this crisis will end. Thus, there an urgent need for treatments that improve prognosis seriously affected patients. Multiple viruses including HIV, MERS-CoV (coronavirus responsible Middle East Respiratory Syndrome, MERS), SARS-CoV SARS) SARS-CoV-2 use a mechanism known -1 programmed ribosomal...
Abstract Background: Multiple viruses including HIV, MERS-CoV (coronavirus responsible for Middle East Respiratory Syndrome, MERS), SARS-CoV SARS) and SARS-CoV-2 COVID-19) use a mechanism known as -1 programmed ribosomal frameshifting (-1 PRF) to successfully replicate. possesses unique RNA pseudoknotted structure that stimulates PRF. Recent experiments identified small molecules antiviral agents can bind the pseudoknot disrupt its stimulation of Targeting PRF in impair viral replication...