A5091342789- Dialysis and Renal Disease Management
- Central Venous Catheters and Hemodialysis
- Vascular Procedures and Complications
- Hemodynamic Monitoring and Therapy
- Chronic Kidney Disease and Diabetes
- Acute Kidney Injury Research
- Muscle and Compartmental Disorders
- Blood Pressure and Hypertension Studies
- Health Systems, Economic Evaluations, Quality of Life
- Body Composition Measurement Techniques
- Electrolyte and hormonal disorders
- Cardiac Arrhythmias and Treatments
- Heart Failure Treatment and Management
- Potassium and Related Disorders
- Renal and Vascular Pathologies
- Pharmacological Effects and Toxicity Studies
- Renal function and acid-base balance
- Peripheral Artery Disease Management
- Gestational Diabetes Research and Management
- Pregnancy and preeclampsia studies
- Blood properties and coagulation
- Heparin-Induced Thrombocytopenia and Thrombosis
- Electrical and Bioimpedance Tomography
- Intramuscular injections and effects
- Renal Diseases and Glomerulopathies
University of Glasgow
2023
Western University
2011-2021
Lawson Health Research Institute
2019
London Health Sciences Centre
2006-2017
Heidelberg University
2016
Columbia College - Missouri
2016
Johnson University
2016
Rutgers, The State University of New Jersey
2016
John Wiley & Sons (United States)
2016
Hudson Institute
2016
Regular vascular access blood flow (Qa) surveillance is recommended to detect graft stenosis; however, there little evidence that monitoring and correcting with angioplasty improves survival. This blinded, randomized, controlled trial of 112 patients studied time thrombosis loss, comparing monthly Qa plus standard (dynamic venous pressure physical examination) (treatment group) alone (control group). Only the treatment group was referred for angiogram if <650 ml/min or a 20% decrease in from...
Patients undergoing conventional maintenance hemodialysis typically receive three sessions per week, each lasting 2.5-5.5 hours. Recently, the use of more intensive (>5.5 hours, to seven times week) has increased, but effects these regimens on survival are uncertain. We conducted a retrospective cohort study examine whether associates with better than hemodialysis. identified 420 patients in International Quotidian Dialysis Registry who received home France, United States, and Canada between...
Complications related to inadequate volume management are common during hemodialysis. This trial tested the hypothesis that availability of an intradialytic blood monitoring (IBVM) device improves fluid removal, reducing morbidity. A six-center, randomized with 6 mo intervention comparing IBVM using Crit-Line versus conventional clinical was conducted. The average rate non–access-related hospitalizations compared across treatment groups Poisson regression. Mortality analysis used Kaplan...
Frequent hemodialysis requires using the vascular access more often than with conventional hemodialysis, but whether this increases risk for access-related complications is unknown. In two separate trials, we randomly assigned 245 patients to receive in-center daily (6 days per week) or (3 and 87 home nocturnal nights 12 months. The primary outcome was time first event (repair, loss, hospitalization). Secondary outcomes were all repairs losses. Daily Trial, 77 (31%) of had a event: 33 15...
Whether the duration of hemodialysis treatments improves outcomes remains controversial. Here, we evaluated survival and clinical changes associated with converting from conventional (mean=3.75 h/treatment) to in-center nocturnal (mean=7.85 h/treatment). All 959 consecutive patients who initiated for first time in 77 Fresenius Medical Care facilities during 2006 2007 were eligible. We used Cox models compare risk mortality 2 years follow-up a 1:3 propensity score-matched cohort 746 2062...
Most patients with end-stage kidney disease value their health-related quality of life (HRQoL) and want to know how it will be affected by dialysis modality. We extended the findings two prior clinical trial reports estimate effects frequent compared conventional hemodialysis on additional measures HRQoL. The Daily Trial randomly assigned 245 receive (six times per week) or (three in-center hemodialysis. Nocturnal 87 nocturnal home All were randomization, an average feeling thermometer score...
Platelet counts, coagulation factors, and the fibrinolytic system were studied in seven regular dialysis patients during course of haemodialysis by parallel flow (Gambro-Alwall) coil (Travenol Ultra-Flo 100) dialysers. Significant falls patients' platelet counts rises their factor V levels found with both systems. The changes more pronounced over a Gambro-Alwall dialysis, when significant partial thromboplastin clotting time plasminogen also noted. These haemostatic associated retention...
Summary Background and objectives Surrogate markers such as creatinine, cystatin C (CysC), beta trace protein (BTP) have been used to estimate GFR (eGFR). The accuracy of eGFR may be altered with hyperfiltration differences in filtration fraction (FF). It is hypothesized that the creatinine for affected by different effective renal plasma flow (ERPF). Design, setting, participants, & measurements A total 127 pediatric patients various diseases underwent simultaneous using 51 Cr-EDTA scan...
According to the Barker hypothesis, intrauterine growth restriction and premature delivery adversely affect cardiovascular health in adult life. The association of childhood hypertension as a risk factor birth weight has been understudied. In prospective cohort study, authors evaluated effect weight, gestational age, maternal prepregnancy body mass index (BMI), child BMI z score at time enrollment on systolic diastolic blood pressure (BP) 3024 (1373 women) consecutive outpatient clinic...
The International Quotidian Dialysis Registry was designed to collect data describing treatments, characteristics, and outcomes of patients treated with quotidian hemodialysis (HD) worldwide. In July 2004, North American centers were first invited enroll patients. By March 1, 2005, a total 70 nocturnal 8 short-daily HD from three Canadian two US enrolled. As recruitment continues, projected enrollment for 2005 may exceed 200 America alone. Preliminary analyses indicate that the current...
Pulmonary hypertension gives an indication of poor prognosis in adult respiratory distress syndrome (ARDS) complicating sepsis. In this study, we examined the role platelet and vasoactive amine, serontonin, pulmonary accompanying septic ARDS. The lack any significant difference number (Δ + 3.9 ± 8.4, × 103/mm3) or serum serotonin – 0.03 0.06 nm/mm3) across vascular bed (pulmonary artery minus vein), would suggest that sequestration and/or release is not a major factor However, did note...
In previous reports of the Frequent Hemodialysis Network trials, frequent hemodialysis (HD) reduced extracellular fluid (ECF) and left ventricular mass (LVM), with more pronounced effects observed among patients low urine volume (UVol). We analyzed effect HD on interdialytic weight gain (IDWG) a time-integrated estimate ECF load (TIFL). also explored whether sodium loading contributed to change in LVM over study period. Treatment parameters were for modification by UVol dialysate-to-serum...