A5027163959- Photochemistry and Electron Transfer Studies
- Radical Photochemical Reactions
- Oxidative Organic Chemistry Reactions
- Porphyrin and Phthalocyanine Chemistry
- Molecular Sensors and Ion Detection
- Luminescence and Fluorescent Materials
- Synthesis and Properties of Aromatic Compounds
- Cyclopropane Reaction Mechanisms
- Asymmetric Synthesis and Catalysis
- Vanadium and Halogenation Chemistry
- Organic Chemistry Cycloaddition Reactions
- Sulfur-Based Synthesis Techniques
- Analytical Chemistry and Chromatography
- Photochromic and Fluorescence Chemistry
- Free Radicals and Antioxidants
- Lanthanide and Transition Metal Complexes
- Protein Interaction Studies and Fluorescence Analysis
- Inorganic and Organometallic Chemistry
- Organic and Inorganic Chemical Reactions
- Molecular Junctions and Nanostructures
- Fluorine in Organic Chemistry
- Synthesis of Organic Compounds
- Polyoxometalates: Synthesis and Applications
- Spectroscopy and Quantum Chemical Studies
- X-ray Diffraction in Crystallography
Williams (United States)
2013-2025
William & Mary
2014-2025
Colonial Williamsburg Foundation
2020
Eastern Virginia Medical School
2005
Old Dominion University
2005
Tohoku University
1989
AT&T (United States)
1986-1988
Alcatel Lucent (Germany)
1985-1986
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT1,2,4,6-Cycloheptatetraene: the key intermediate in arylcarbene interconversions and related C7H6 rearrangementsRobert J. McMahon, Christopher Abelt, Orville L. Chapman, Jeffery W. Johnson, Curtis Kreil, Jean Pierre LeRoux, Anne M. Mooring, Paul R. WestCite this: Am. Chem. Soc. 1987, 109, 8, 2456–2469Publication Date (Print):April 1, 1987Publication History Published online1 May 2002Published inissue 1 April...
The synthesis and photochemical properties of 1-(4-methyl-1,2,3,4-tetrahydrobenzo[f]quinolin-8-yl)propan-1-one (7) 2,2-dimethyl-1-(4-methyl-1,2,3,4-tetrahydrobenzo[f]quinolin-8-yl)propan-1-one (8) are reported. These compounds models for PRODAN, 6-propionyl-2-(dimethylamino)naphthalene, where the dialkylamino group is forced to remain coplanar with naphthalene ring. Stokes shifts 7 8 in various solvents compared those PRODAN. absorption emission transitions calculated by AM1 semiempirical...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPreparation, spectroscopic properties, and characterization of novel peroxo complexes vanadium(V) molybdenum(VI) with nicotinic acid N-oxideCirila Djordjevic, Bruce C. Puryear, Nikola Vuletic, Christopher J. Abelt, Sandra SheffieldCite this: Inorg. Chem. 1988, 27, 17, 2926–2932Publication Date (Print):August 1, 1988Publication History Published online1 May 2002Published inissue 1 August...
The synthesis and photophysical properties of 7-(dimethylamino)-3,4-dihydrophenanthren-1(2H)-one (7) 3-(dimethylamino)-8,9,10,11-tetrahydro-7H-cyclohepta[a]naphthalen-7-one (8) are reported. These compounds possess a cycloalkanone substructure that controls the extent twisting carbonyl group. six-membered ring in 7 forces group to be coplanar with naphthalene ring, whereas seven-membered 8 induces significant twist. Both have PRODAN (6-propionyl-2-(dimethylamino)naphthalene, 1). Comparing...
The effects of intramolecular hydrogen-bonding on the fluorescence behavior three derivatives 6-propionyl-2-dimethylaminonaphthalene are reported. H-bonding revealed through comparisons with corresponding reference compounds in which H-bond-donating hydroxyl groups replaced methoxy groups. In toluene, H bonding gives rise to a dramatic increase intensity but only slight red shift position. This is attributed decreased efficiency intersystem crossing due an energy n → π* triplet state. bond...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis and photochemistry of some anthraquinone-substituted .beta.-cyclodextrinsAngela M. Aquino, Christopher J. Abelt, Karen L. Berger, Colleen Darragh, Sarah E. Kelley, Michael V. CossetteCite this: Am. Chem. Soc. 1990, 112, 15, 5819–5824Publication Date (Print):July 1, 1990Publication History Published online1 May 2002Published inissue 1 July...
The synthesis and photophysical properties of 7-cyano-3,4-dihydro-2H-1,4-ethano-benzo[g]quinoline 3,4-dihydro-2H-1,4-ethano-7-propionyl-benzo[g]quinoline are reported. These compounds possess a quinuclidine substructure that locks the tertiary amino group perpendicular to naphthalene ring. Their excited states models for twisted 2-(dimethylamino)-6-naphthonitrile (DMANN) 6-propionyl-2-(dimethylamino)naphthlene (PRODAN). In contrast DMANN PRODAN, fluorescence these derivatives is strongly...
The preparation of two 1-acyl-8-pyrrolylnaphthalenes (5 and 6) one pyrrolone (8) are reported along with the issues complicating preparations other compounds. photophysical behavior fused, planar derivative 6 is explored in detail. fluorescence shows solvato-chromism due to intramolecular charge transfer excited state enhanced emission protic solvents. intensity increases very linearly H-bond-donating strength solvent. Preferential solvation studies, multilinear regression analysis...
Two extrinsic fluorescent probes, 3-(dimethylamino)-8,9,10,11-tetrahydro-7H-cyclohepta[a]naphthalen-7-one (1) and 7-(dimethylamino)-2,3-dihydrophenanthren-4(1H)-one (2), are used to probe the unfolding of human serum albumin by sodium dodecyl sulfate (SDS). These probes respond separately polarity H-bond-donating ability their surroundings. Competitive binding experiments show that fluorophore 1 binds site I (domain IIA) 2 II IIIA). The local acidity in is out sensing range 1, whereas...
The local solvent acidities (SA scale) of six 6-carbonyl-2-aminonaphthalene derivatives as β-cyclodextrin complexes in water are determined through fluorescence quenching. polarities (E(T)(N) the shift emission center-of-mass. apparent SA values reflect structure surrounding guest’s carbonyl group, whereas E(T)(N) reveal net polarity entire guest molecule. Comparison these affords greater insight into structures host–guest complexes. Derivatives 1 and 5 show unusually large acidities,...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStereoselective azine formation in the decomposition of phenyldiazomethanesChristopher J. Abelt and Jennifer M. PleierCite this: Am. Chem. Soc. 1989, 111, 5, 1795–1799Publication Date (Print):March 1, 1989Publication History Published online1 May 2002Published inissue 1 March 1989https://pubs.acs.org/doi/10.1021/ja00187a037https://doi.org/10.1021/ja00187a037research-articleACS PublicationsRequest reuse permissionsArticle...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTElectron transfer induced dimerization of spiro[2.4]heptadiene. A facile radical cation Diels-Alder reactionHeinz D. Roth, Marcia L. M. Schilling, and Christopher J. AbeltCite this: Am. Chem. Soc. 1986, 108, 19, 6098–6099Publication Date (Print):September 1, 1986Publication History Published online1 May 2002Published inissue 1 September 1986https://pubs.acs.org/doi/10.1021/ja00279a102https://doi.org/10.1021/ja00279a102research-articleACS...
Fluorescence from dialkylamino donor–acyl acceptor substituted 1,8-naphthalene derivatives can occur either a planar (PICT) or twisted (TICT) intramolecular charge transfer excited state. The photophysical properties of 8-acetyl-1-(dimethyl-amino)naphthalene (3) and 8-pivaloyl-1-(dimethyl-amino)naphthalene (4) are compared with 1-methyl-2,3-dihydronaphtho[1,8-bc]azepin-4(1H)-one (5). In 3 4, both the carbonyl amino groups forced to twist out plane naphthalene ring. 5, these nearly coplanar...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of a Water-Soluble Dicyanoanthracene as Cap For .beta.-CyclodextrinMichael F. Acquavella, Mary E. Evans, Steven W. Farraher, Cedrine J. Nevoret, and Christopher AbeltCite this: Org. Chem. 1994, 59, 10, 2894–2897Publication Date (Print):May 1, 1994Publication History Published online1 May 2002Published inissue 1 1994https://pubs.acs.org/doi/10.1021/jo00089a041https://doi.org/10.1021/jo00089a041research-articleACS PublicationsRequest reuse...
We have synthesized a series of 2-aminoethoxydiphenyl borate (2-APB, 2,2-diphenyl-1,3,2-oxazaborolidine) analogs and tested their ability to inhibit thrombin-induced Ca<sup>2+</sup> influx in human platelets. The were either by adding various substituents the oxazaborolidine ring (methyl, dimethyl, <i>tert</i>-butyl, phenyl, methyl pyridyl) or increasing size seven- nine-membered rings. NMR analysis boron-containing suggests that each them exist as structure through formation an N→B...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTElectron-transfer-induced rearrangements: radical cations of bridged bicyclobutanesChristopher J. Abelt, Heinz D. Roth, and Marcia L. M. SchillingCite this: Am. Chem. Soc. 1985, 107, 14, 4148–4152Publication Date (Print):July 1, 1985Publication History Published online1 May 2002Published inissue 1 July 1985https://pubs.acs.org/doi/10.1021/ja00300a010https://doi.org/10.1021/ja00300a010research-articleACS PublicationsRequest reuse permissionsArticle...
Derivatives of 2-propionyl-6-dimethylaminonaphthalene (PRODAN) with twisted carbonyl groups were investigated as highly responsive sensors H-bond donating ability. The PRODAN derivative bearing a pivaloyl group (4) was prepared. torsion angle between the and naphthalene is 26° in crystal. It shows solvatochromism that similar to five other derivatives (1–3, 5, 6). Twisted-carbonyl 3, 4, 6 show strong fluorescence quenching protic solvents. order magnitude linearly related ability solvent...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT.beta.-Cyclodextrin as a molecular reaction vessel: reactions of included phenylmethyldiazirineChristopher J. Abelt and Jennifer M. PleierCite this: Org. Chem. 1988, 53, 10, 2159–2162Publication Date (Print):May 1, 1988Publication History Published online1 May 2002Published inissue 1 1988https://pubs.acs.org/doi/10.1021/jo00245a005https://doi.org/10.1021/jo00245a005research-articleACS PublicationsRequest reuse permissionsArticle...
1-Propionyl-5-dimethylaminonaphthalene (8, 1,5-Prodan) and two derivatives where the amino group is constrained in a seven-membered (9) five-membered (10) ring are prepared. All three exhibit strong fluorescence similar degrees of solvatochromism. Their strongly quenched alcohol solvents. Because 9 especially 10 forced to be coplanar with naphthalene ring, photophysical behavior all suggests that emission arises from planar excited state (planar intramolecular charge transfer).
The Rosés and Bosch model for preferential solvation is used to analyze the fluorescence behavior of two PRODAN derivatives in binary solvents with one or protic components. results suggest that excited form H-bonds. allows determining characteristics singly H-bonded states. They show red-shifted but relatively little quenching. In contrast, doubly states are significantly quenched when solvent a strong H-bond donor (large SA value). With there interaction even though have very different...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIon pairs from electron donor-acceptor systems: a comparison between picosecond and CIDNP studiesP. M. Rentzepis, D. W. Steyert, H. Roth, C. J. AbeltCite this: Phys. Chem. 1985, 89, 19, 3955–3960Publication Date (Print):September 1, 1985Publication History Published online1 May 2002Published inissue 1 September 1985https://pubs.acs.org/doi/10.1021/j100265a004https://doi.org/10.1021/j100265a004research-articleACS PublicationsRequest reuse...
Fluorescence quenching of 6A,6D(C)-(9, 10-dicyanoanthracene-2,6-disulfonyl)-β-cyclodextrin (DCA-β-CD) by several amines (1–6) has been investigated. Apparent Stern–Volmer constants, which are the sum dynamic and static (binding) components, have determined. Quenching constants with potassium 9, 10-dicyanoanthracene-2,6-disulfonate (DCA-DS) binding β-CD determined as approximations for respectively. DCA-β-CD does not bind all more strongly than despite its greater hydrophobic surface area....
The coordination chemistry of Hg(II) with tris[(1-methylimidazol-2-yl)methyl]amine (TMIMA) was investigated. structures [Hg(TMIMA)2](ClO4)2 (1), [Hg(TMIMA)(NCCH3)](ClO4)2 (2) and [Hg(TMIMA)Cl]2(HgCl4) (3) were characterized by X-ray crystallography. Complex 1 has six strong Hg–Nimidazoyl bonds ranging from 2.257(5) to 2.631(6) Å. Ligand geometry suggests the Hg–N(NR3) distances 2.959(6) Å in reflects weak bonding interactions. This complex a 199Hg chemical shift −1496 ppm, significantly...