A5003052040- Neural dynamics and brain function
- Neural and Behavioral Psychology Studies
- Visual perception and processing mechanisms
- Functional Brain Connectivity Studies
- Face Recognition and Perception
- EEG and Brain-Computer Interfaces
- Memory and Neural Mechanisms
- Neural Networks and Applications
- Memory Processes and Influences
- Neuroscience and Neuropharmacology Research
- Psychology of Moral and Emotional Judgment
- Decision-Making and Behavioral Economics
- Intelligent Tutoring Systems and Adaptive Learning
- Neurotransmitter Receptor Influence on Behavior
- Visual Attention and Saliency Detection
- Fractal and DNA sequence analysis
- Advanced Neuroimaging Techniques and Applications
- Neuroscience and Music Perception
- Brain Tumor Detection and Classification
- Seismic Imaging and Inversion Techniques
- Seismic Waves and Analysis
- Receptor Mechanisms and Signaling
- Traditional Chinese Medicine Studies
- Molecular spectroscopy and chirality
- Motor Control and Adaptation
Charité - Universitätsmedizin Berlin
2013-2022
Freie Universität Berlin
2019-2022
University of Potsdam
2021-2022
Humboldt-Universität zu Berlin
2015-2022
PATH To Reading
2017
Bernstein Center for Computational Neuroscience Berlin
2012-2016
Orthopädische Universitätsklinik
2014
It is well established that learning can occur without external feedback, yet normative reinforcement theories have difficulties explaining such instances of learning. Here, we propose human observers are capable generating their own feedback signals by monitoring internal decision variables. We investigated this hypothesis in a visual perceptual task using fMRI and confidence reports as measure for process. Employing novel computational model which guided confidence-based signals, found...
Visual working memory (VWM) is used to maintain visual information available for subsequent goal-directed behavior. The content of VWM has been shown affect the behavioral response concurrent input, suggesting that representations originating from and sensory input draw upon a shared neural substrate (i.e., <i>sensory recruitment</i> stance on storage). Here, we hypothesized maintained in would enhance matches VWM. To test this hypothesis, measured fMRI BOLD responses task-irrelevant stimuli...
The premature aging hypothesis of alcohol dependence proposes that the neurobiological and behavioural deficits in individuals with are analogous to those chronological aging. However, date no systematic evidence for this has been provided. To test hypothesis, 119 alcohol-dependent subjects 97 age- gender-matched healthy control underwent structural MRI. Whole-brain grey matter volume maps were computed from MRI scans using voxel-based morphometry parcelled into a comprehensive set...
Research on metacognition-thinking about thinking-has grown rapidly and fostered our understanding of human cognition in healthy individuals clinical populations. Of central importance is the concept metacognitive performance, which characterizes capacity an individual to estimate report accuracy primary (type 1) cognitive processes or actions ensuing from these processes. Arguably one biggest challenges for measures performance their dependency objective type 1 although more recent methods...
The human ability to introspect on thoughts, perceptions or actions - metacognitive has become a focal topic of both cognitive basic and clinical research. At the same time it increasingly clear that currently available quantitative tools are limited in their make unconfounded inferences about metacognition. As step forward, present work introduces comprehensive modeling framework metacognition allows for noise biases during readout decision values at confidence reporting stage. model...
Automatic classification of local seismic events which are only recorded at single stations poses great challenges because weak hypocentre constraints. This study investigates how single-station event clusters relate to geographic regions and common source processes. Typical applications arise in networks where reliable ground truth by a dense temporal network precedes or follows sparse (permanent) installation. The signals for this comprise 3-month subset from field campaign map subduction...
Abstract With progress in magnetic resonance imaging technology and a broader dissemination of state-of-the-art facilities, the acquisition multiple neuroimaging modalities is becoming increasingly feasible. One particular hope associated with multimodal development reliable data-driven diagnostic classifiers for psychiatric disorders, yet previous studies have often failed to find benefit combining modalities. As disorder established neurobiological effects at several levels description,...
Gaze direction and especially direct gaze is a powerful nonverbal cue that plays an important role in social interactions. Here we studied the neural mechanisms underlying privileged access of to visual awareness. We performed functional magnetic resonance imaging healthy human volunteers who were exposed faces with or averted under continuous flash suppression, thereby manipulating their awareness faces. A processing network comprising fusiform face area (FFA), superior temporal sulcus,...
Reinforcement learning algorithms have a long-standing success story in explaining the dynamics of instrumental conditioning humans and other species. While normative reinforcement models are critically dependent on external feedback, recent findings field perceptual point to crucial role internally generated signals based subjective confidence, when feedback is not available. Here, we investigated existence such confidence-based key domain reinforcement-based learning: conditioning. We...
Objective We investigated the potential of computer‐based models to decode diagnosis and lifetime consumption in alcohol dependence (AD) from grey‐matter pattern information. As machine‐learning approaches psychiatric neuroimaging have recently come under scrutiny due unclear generalization opacity algorithms, our investigation aimed address a number methodological criticisms. Method Participants were adult individuals diagnosed with AD ( N = 119) substance‐naïve controls 97) ages 20‐65 who...
Predictive processing posits that perception emerges from inferential processes within a hierarchical cortical system. Alterations of these may result in psychotic experiences, such as hallucinations and delusions. Central to the predictive account psychosis is notion aberrant weights attributed prior information sensory input. Based on previous perceptual choices represent relevant source information, we here asked whether propensity towards experiences be related altered choice history...
Abstract It is well established that learning can occur without external feedback, yet normative reinforcement theories have difficulties explaining such instances of learning. Recently, we reported on a confidence-based learn-ing model for the case perceptual (Guggenmos, Wilbertz, Hebart, & Sterzer, 2016), according to which brain capitalizes internal monitoring processes when no feedback available. In model, confidence prediction errors – difference between current and expected serve...
Visual working memory (VWM) allows for keeping visual information available upcoming goal-directed behavior, while new input is processed concurrently. Interactions between the mnemonic and perceptual systems cause VWM to affect processing of in a content-specific manner: that initially suppressed from consciousness detected faster when it matches rather than mismatches content VWM. It currently under debate whether such influences on perception occur prior or after conscious access. To...
Abstract Feedback is central to most forms of learning, and its reliability therefore critical. Here, we investigated the effects corrupted, hence unreliable, feedback on perceptual inference. Within framework Bayesian inference, hypothesised that corrupting in a demanding task would compromise sensory information processing bias inference towards prior if available. These hypotheses were examined by simulation two behavioural experiments with visual detection (experiment 1) discrimination...
Event Abstract Back to Altered contextual modulation of primary visual cortex responses in schizophrenia Kiley Seymour1, 2*, Timo Stein1, Lia Sanders1, Matthias Guggenmos1, Ines Theophil1 and Philipp Sterzer1 1 Charite', Psychology Psychiatry, Germany 2 Macquarie University, Cognitive Science/Centre for Cognition & its Disorders, Australia Schizophrenia is an illness commonly linked high-level cognitive dysfunction, typically manifesting itself disorganized thoughts, delusions...
Multivariate pattern analysis (MVPA) methods such as decoding and representational similarity (RSA) are growing rapidly in popularity for the of magnetoencephalography (MEG) data. However, little is known about relative performance characteristics specific dissimilarity measures used to describe differences between evoked activation patterns. Here we a multisession MEG dataset qualitatively characterize range quantitatively compare them with respect classification accuracy (for decoding)...
Perceptual learning is the improvement in perceptual performance through training or exposure. Here, we used fMRI before and after extensive behavioral to investigate effects of on recognition objects under challenging viewing conditions. Objects belonged either trained untrained categories. Trained categories were further subdivided into exemplars coupled with high low monetary rewards during training. After a 3-day training, object was markedly improved. Although there considerable...