Ukrainian medical students face a high risk of mental health issues, including depression and anxiety, which exacerbated by the COVID-19 pandemic ongoing war. This study examines their one year into war, focusing on depression, coping strategies while identifying vulnerable groups. A cross-sectional was conducted during 2023, involving 506 from Bogomolets National Medical University in Kyiv 380 Split, Croatia, as control group. higher proportion had history problems (37.5%) compared to...

Introduction Takayasu arteritis (TAK) is a granulomatous inflammation of vessels large diameter, mainly affecting the aorta and its proximal branches, which more common in young women. The incidence coronary artery disease TAK unknown not sufficiently studied. Material Methods A literature review was performed for period 2003 to 2023 using search PubMed Scopus scientific databases. We used following key words academic journal data-bases: “Takayasu arteritis”, “coronary angiography”,...

Background The SarQoL, a quality-of-life questionnaire specific to sarcopenia, was developed in 2015 and has since been translated into number of other languages. main reason introduce this new Ukrainian version the measure sarcopenic individuals' perceptions regarding their positions life context culture value systems. Methods using forward-backward approach with pre-test. A total 49 participants were recruited for validation study. Sarcopenia diagnosed according Ishii test. analyses...

Effective prevention of thromboembolism is essential for patients with mechanical prosthetic heart valves. For this group patients, vitamin K antagonists (VKAs) remain the drug choice despite widespread use new anticoagulants in other diseases. As a consequence, warfarin resistance remains serious challenge physicians. The current report describes 65-year-old male patient that had aortic valve implanted due to severe insufficiency after infective endocarditis. Despite consistent increases...

Introduction. The problem of cardiovascular morbidity and mortality remains an urgent issue modern medicine, arterial stiffness is its independent predictor. Lively discussions about the correct approach to prevention treatment comorbid conditions – increased vascular as influential factor events decreased bone mineral density (osteoporosis), primarily arise against background need safety calcium vitamin D supplements. purpose was search for literature data possible common pathogenetic links...

cardiorenal syndrome includes a spectrum of disorders the heart and kidneys, in which acute or chronic dysfunction one organ can lead to development another organ. Changes hemodynamics, activation renin-angiotensin-aldosterone system, metabolic disorders, inflammation, etc., are important pathogenesis syndrome. The purpose this article is analyze systematize available contemporary scientific data on role renal biomarkers stratifying risk development, mortality repeated hospitalizations due...

Myocardial bridges (MM) are common congenital anomaly of the coronary arteries (CA) with location a separate bundle myocardial muscle fibers over any epicardial vessel, most often middle segment left anterior descending artery (LAD). In patients, MM has benign course, though in 25% cases, it can cause stable or unstable angina, infarction non‑obstructive CA (MINOCA), paroxysmal rhythm disturbances, and sudden cardiac death. The pathophysiological mechanisms development fatal non‑fatal...

Sarcopenia is characterized by a loss of skeletal muscle mass, decrease in strength and/or physical performance, and one the main causes for limiting daily activities elderly. This associated with an increased incidence many adverse events such as dysfunction, falls, frailty, hospitalization, disability, mortality. Primary (considered part aging process) secondary sarcopenia (due to malabsorption, immobility/bed rest, starvation, hypothyroidism, osteoporosis, immune-mediated rheumatic...

To assess the long-term effects of juvenile idiopathic arthritis in adulthood, unified diagnostic methods for articular and extra-articular lesions should be used which depend on variants, disease activity treatment. The objective research was to compare clinical manifestations adult patients with different arthritis-specific immunogenic markers evaluate their impact damage.Materials methods. We observed 132 young variants. According genetic/immunological following groups were formed: Group...

Relevance. The existence of associations between histocompatibility antigens and JIA variants has been proved. There is no consensus that the JIAs associated with HLA-B27 antigen are transformed in adulthood into other diseases for which it necessary to revise diagnosis, according adult classification rheumatic diseases. Is this one process began childhood continues adulthood, whether these two processes begin have common signs differences? few data about hallmarks disease outcome adulthood....

The aim — to determine differences in the structure and function of heart, arterial stiffness, resistive pulsative loads ventricular‑arterial connection patients with hypertension, confirmed heart failure (HF) preserved ejection fraction, depending on age gender.Materials methods. study included 115 (62 (53.9 %) men 53 (46.1 women, average 67.3 ± 9.7 years) a diagnosis HF EF IIA or IIB stage, II III functional class according NYHA, left ventricular (LV) fraction (EF) ≥ 50 % signs LV...

Objective: To compare the indices of aortic blood pressure (ABP) and pulse wave, bone mineral density (BMD) in elderly female patients with mild-moderate uncomplicated arterial hypertension (AH) Design method: 44 women AH stage I-II 30 practically healthy were involved to study. Groups didn‘t differ age (correspondingly 69.1 ± 0.7; 69.3 1.2 years), average duration postmenopausal period (18.4 0.9; 19.4 years). All underwent general clinical a laboratory examination, daily monitoring (BP)...

Болезнь Бехчета (ББ) относится к системным васкулитам, поражающим сосуды любого калибра (малого, среднего и большого) типа (артерии, вены капилляры). ББ характеризуется рецидивирующими язвами в полости рта и/или половых органов, сопровождающимися воспалительными поражениями кожи, глаз, суставов, желудочно-кишечного тракта центральной нервной системы. Патология вен тромбозы являются отличительными признаками ББ. Тем не менее поражение сердца артерий также является важным аспектом этого...

<p style="background: white; margin: 0cm 1.9pt 0pt; text-align: justify; line-height: 150%; text-indent: 24pt; vertical-align: top;"><span style="line-height: font-size: 14pt;"><span style="font-family: Times New Roman;">Основним критерієм ефективності навчального процесу є засвоєння студентом базисних знань та спроможність до реального їх приросту, а також формування навичок професійно-орієнтованої діяльності. Фактично набуваються компетенції, котрі формують нову модель...

Запропоновано регламент підсумкового модульного контролю при впровадженні Європейської кредитно-трансферної системи організації навчального процесу, що сприяє підвищенню об’єктивності оцінювання знань, умінь та практичних навичок студентів.

Background. Osteoporosis is actually today's problem, as it affects the quality and length of life, increases risk fragility fractures, which leads to significant medical, social, economic problems. One reasons for development secondary osteoporosis use vitamin K new oral anticoagulants, increasing. The purpose this review was analyze literature data regarding impact anticoagulants on bone state, its complications in order improve awareness doctors various specialties. Materials methods....

Abstract This case report describes the occurrence of symmetrical dactylitis toes combined with chilblain-like acral lesions in a 32-year-old female patient 19 days after mild coronavirus infection. The article addresses existing problems managing patients COVID-19 daily clinical practice. Scientific evidence is pointing to growing number cases articular and skin involvement associated COVID-19. However, it remains unclear what approaches use treatment such patients.

Background. Cardiovascular disease (CVD) is one of the main causes morbidity and mortality among adults worldwide. On another hand, obstructive sleep apnea syndrome (OSAS) common in patients with CVD, can worsen prognosis due to late diagnosis. 
 Aim: analyze summarize published researches about interrelation between CVD OSAS, its influence on effects continuous airway pressure (CPAP) treatment OSAS order pay attention potential risks, improve investigation this management.
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The aim — to perform a comparative analysis of the indices central aortic pressure and pulse wave, bone mineral density (BMD) in elderly female patients with uncomplicated essential hypertension.Materials methods. study involved 30 women hypertension II stage, 2 degree, mean age 69.3 ± 0.9 years, post­menopausal duration 17.7 1.1 years 25 practically healthy aged 65.6 1.6 period 15 years. All underwent general clinical laboratory examination, daily monitoring blood (BP) echocardiography....

Relevance. It is known that the poly-articular variant of JIA associated with significant articular and extra-articular damages predominant lesions small medium joints limitation their function development ankylosis, requiring surgical intervention in these patients.
 Objective. The aim study was to evaluate risk factors adults work out a prognostic model for development.
 Materials methods. included 45 adult patients (RF+ RF-) JIA. Retrospective analysis medical records made,...

Objective: The aim was to compare the frequency of NT-pro-BNP elevation in phenotypes mild arterial hypertension (AH) pts with left heart structural changes and failure (HF) symptoms based on E/E′> at rest, E/E′>13 only after exercise E/E′<13 both rest exercise. Design method: Materials methods. We consequently enrolled 84 hemodynamic stable patients AH ventricular myocardial index LVMI > 115 g/m2 (for male) 95 female), atrial volume LAVI 34 ml/m2, dived them three groups. Group A included...

Objective: was to assess the association between carotid – femoral pulse wave velocity (PWV) and serum 25(OH) vitamin D level in postmenopausal women with controlled uncomplicated hypertension (UH). Design method: In 28 69.2 ± 0.85 years old mild-moderate UH 25 healthy ones matched for age (65.6 1.58 years), length of menopause (17.4 1.05 vs 15.0 1.64 body mass index (28.3 0.76 kg/m2 27.7 0.8 kg/m2), brachial systolic blood pressure - BP (126.2 2,53 mmHg 120.0 2,54 mmHg, all p > 0.05),...