- Childhood Cancer Survivors' Quality of Life
- Glioma Diagnosis and Treatment
- Testicular diseases and treatments
- Pharmacological Effects and Toxicity Studies
- Genetic and Kidney Cyst Diseases
- Epilepsy research and treatment
- Bone and Joint Diseases
- Photoreceptor and optogenetics research
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Renal cell carcinoma treatment
- Electrolyte and hormonal disorders
- Chemotherapy-induced organ toxicity mitigation
- Retinal Development and Disorders
Minerva Foundation
2016-2017
Tampere University
2004-2012
Tampere University Hospital
2004-2012
Abstract Background A population based cross‐sectional study was used to examine the prevalence of metabolic syndrome and its components in childhood brain tumor survivors. Procedure Fifty‐two survivors were examined at a mean age 14.4 years (range 3.8–28.7). Lipid glucose metabolism, thyroid function, plasma uric acid evaluated. Fat mass fat percentage assessed by dual‐energy X‐ray absorptiometry (DXA). Metabolic defined on International Diabetes Federation criteria. Results Ten (19%)...
Abstract Background This study was designed to evaluate the renal consequences of treatment brain tumor patients diagnosed in childhood. Procedure One hundred four primary before 17 years age from 1983 1997 had been treated Tampere University Hospital, Finland. Of 80 survivors 52 (65.0%) were examined at a median 14.4 (range 3.8–28.7) and 6.0 1.2–14.8) after last treatment. The main outcome measures blood pressure (BP), function, calcium metabolism. Results Eight (15.4%) hypertensive....
Abstract Aim: To determine the prevalence of low bone mineral density among children surviving brain tumours and to identify possible factors underlying impaired health. Methods: Cross‐sectional study; total body (TBBMD), fat mass (FM) lean (LBM) were measured by dual‐energy X‐ray absorptiometry (DXA) in 46 tumour patients aged from 3.8 28.7 y (mean 14.9 y) treated childhood 1.4–14.8 6.4 after end treatment for tumour. Low was defined as TBBMD z score<−2.0. Results: Fifteen had...
Abstract Aim Childhood brain tumour survivors have a high risk of endocrine morbidity. This study evaluated the growth, pubertal development and gonadal function in childhood tumours identified factors associated with problems we observed. Methods The 52 subjects (52% male) were diagnosed 1983–1997 treated for at Tampere University Hospital, Finland. They followed up mean age 14.2 (3.8–28.7) years, 7.5 (1.5–15.1) years after diagnosis. Results We found that 30 (58%) participants had lower...
This population-based cross-sectional study evaluates the clinical value of electroretinography and visual evoked potentials in childhood brain tumor survivors. A flash a checkerboard reversal pattern potential (or alternatively potential) were done for 51 survivors (age 3.8-28.7 years) after mean follow-up time 7.6 (1.5-15.1) years. Abnormal was obtained 1 case, bilaterally delayed abnormal 22/51 (43%) cases. Nine 25 patients with infratentorial location, altogether 12 out 31 (39%) who did...