A5052365065- Advanced biosensing and bioanalysis techniques
- Mass Spectrometry Techniques and Applications
- Analytical Chemistry and Chromatography
- Biosensors and Analytical Detection
- Nanocluster Synthesis and Applications
- Luminescence and Fluorescent Materials
- Microfluidic and Capillary Electrophoresis Applications
- Hemoglobin structure and function
- RNA Interference and Gene Delivery
- Gold and Silver Nanoparticles Synthesis and Applications
- Molecular Sensors and Ion Detection
- Advanced Nanomaterials in Catalysis
- Analytical Methods in Pharmaceuticals
- Nanoplatforms for cancer theranostics
- Quantum Dots Synthesis And Properties
- Analytical Chemistry and Sensors
- Carbon and Quantum Dots Applications
- Erythrocyte Function and Pathophysiology
- Gas Sensing Nanomaterials and Sensors
- Electrochemical sensors and biosensors
- Advanced Photocatalysis Techniques
- Advanced Chemical Sensor Technologies
- Pharmacological Effects and Assays
- Metabolomics and Mass Spectrometry Studies
- Neonatal Health and Biochemistry
Beijing Normal University
2016-2025
Capital University of Economics and Business
2024
Ministry of Education of the People's Republic of China
2024
China Tobacco
2022
Jiujiang University
2020
North China Electric Power University
2020
Bioengineering (Switzerland)
2013
Capital Medical University
2013
Liaoning Planning and Design Institute of Post and Telecommunication
2012
Ghent University
1998-2009
Nanozymes have shown great promise in reactive oxygen species (ROS)-mediated tumor therapy with mitigated side effects but are normally limited by the complex microenvironment (TME). Herein, to overcome adverse of TME, such as hypoxia and high endogenous glutathione (GSH), an aptamer-functionalized Pd@MoO3–x nano-hydrangea (A-Pd@MoO3–x NH) is constructed for high-efficiency cancer therapy. Utilizing irregular shape characteristics nano Pd, A-Pd@MoO3–x NH nanozyme simultaneously exposes...
Most of the nanozymes have been obtained based on trial and error, for which application is usually compromised by enzymatic activity regulation due to a vague catalytic mechanism. Herein, hollow axial Mo–Pt single-atom nanozyme (H-MoN5@PtN4/C) constructed two-tier template capture strategy. The ligand can induce Mo 4d orbital splitting, leading rearrangement spin electrons (↑ ↑ → ↑↓) regulate activity. This creates catalase-like enhances oxidase-like catalyze cascade reactions (H2O2 O2...
This paper describes a visual sensor array for pattern recognition analysis of proteins based on two different optical signal changes: colorimetric and fluorometric, by using types novel blue-emitting collagen protected gold nanoclusters macerozyme R-10 with lower synthetic demands. Eight have been well-discriminated this array, protein mixtures after one-dimensional polyacrylamide gel electrophoresis also could be well-discriminated. The possible mechanism was illustrated validated...
Abstract There are only a few systematic rules about how to selectively control the formation of DNA‐templated metal nanoparticles (NPs) by varying sequence combinations double‐stranded DNA (dsDNA), although many attempts have been made. Herein, we develop facile method for sequence‐dependent fluorescent CuNPs using dsDNA as templates. Compared with random sequences, AT sequences better templates highly CuNPs. Other specific example, GC do not induce These results shed light on directed...
A high-throughput and controllable synthesis of colloidal CsPbX<sub>3</sub> perovskite NCs with tunable properties morphologies was achieved by microwave irradiation within minutes.
A novel dual-emission ratiometric fluorescence probe is designed and developed by linking two parts, positively charged aggregation-induced emission (AIE) organic nanoparticles (OFNs) as the reference negatively Au nanoclusters (Au NCs) response, electrostatic attraction for first time. This can be used not only visual but quantitative determination of Hg2+ well melamine, because red NCs quenched mercury ions recovered due to strong affinity metallophilic Hg2+–Au interaction stronger Hg2+–N....
Abstract Single‐atom nanozymes (SAzymes) have obtained increasing interest to mimic natural enzymes for efficient cancer therapy, while challenged by chemoresistance from cellular redox homeostasis and the interface of reductive species in tumor microenvironment (TME). Herein, a dual single‐atomic ultrathin 2D metal organic framework (MOF) nanosheet multienzyme (Pd/Cu SAzyme@Dzy) is prepared synergistically overcome enhanced catalytic therapy. The Pd SAzyme exhibits peroxidase (POD)‐like...
The electron spin orbital was regulated by sulfur doping of Ti vacancies, which efficiently manipulated flip for enhancing PEC water splitting performance.
Optical antennas with anisotropic metal nanostructures are widely used in the field of fluorescence enhancement based on localized surface plasmons (LSPs). They overcome intrinsic defects low brightness near-infrared (NIR) dyes and can be to develop sensitive NIR sensors for bioapplications. Here, we demonstrate a novel plasmon-enhanced (PEF) system consisting elongated gold nanobipyramids (Au NBPs) antennas, silica, dyes. Silica was chosen as rigid spacer regulate distance between Maximum...
Developing plasmon‐enhanced fluorescence (PEF) technology for identifying important biological molecules has a profound impact on biosensing and bioimaging. However, exploration of PEF application is still at very early stage. Herein, novel PEF‐based core–shell nanostructures as near‐infrared fluorescent turn‐on sensor highly sensitive selective detection pyrophosphate (PPi) in aqueous solution are proposed. This nanostructure gold nanorod (AuNR)@SiO 2 @ meso ‐tetra(4‐carboxyphenyl)...
Abstract Nanogap antennas are plasmonic nanostructures with a strong electromagnetic field generated at the gap region of two neighboring particles owing to coupling collective surface plasmon resonance. They have great potential for improving optical properties fluorophores. Herein, nanogap constructed using an aqueous solution‐based method overcome defects weak fluorescence and photobleaching associated traditional organic dyes, highly sensitive antenna‐based sensing strategy is presented...
Compared with traditional visible light-driven fluorescence visualization (FV), near-infrared (NIR)-induced FV is an interesting and promising method, while photoelectrochemical (PEC) immunoassay sensing possesses the advantages of high sensitivity, low cost, simple instrumentation. We combined PEC NIR-induced together developed a dual readout platform. In this protocol, based on antibody–analyte (i.e., antigen, DNA, RNA) reaction sandwich-type structure, CuInS2 microflowers as matrix...
A highly sensitive and water-soluble "switch-on" fluorescent probe with aggregation-induced emission characteristics was developed for protein quantification visualization. It offers a rapid, economic effective way the assay of complete serum proteins disease-marker proteins.
Four electron-donor-substituted aggregation-induced emission (AIE) compounds, N,N'-bis(4-methoxylsalicylidene)-p-phenylenediamine (BSPD-OMe), N,N'-bis(4-methylsalicylidene)-p-phenylenediamine (BSPD-Me), N,N'-bis(salicylidene)-p-phenylenediamine (BSPD), and N,N'-bis(4-hydroxylsalicylidene)-p-phenylenediamine (BSPD-OH), are designed synthesized. They all found to exhibit controlled self-assembly behaviors good thermal properties. By changing the terminal electron-donor groups, they...
The direct extraction, desorption and ionization of in gel-intact proteins after electrophoresis have been achieved by CNTs-modified paper spray MS at ambient conditions.
Abstract Two compounds, 9,10‐bis[2‐(quinolyl)vinyl]anthracene (BQVA) and 9,10‐bis[2‐(naphthalen‐2‐yl)vinyl]anthracene (BNVA), have been synthesised investigated. Both of them aggregation‐induced enhanced emission (AIEE) properties. Heteroatom‐assisted BQVA shows solvatochromism, reversible chromism properties self‐assembly effects. When increasing the solvent polarities, green solution turns to orange with a redshift fluorescence wavelengths from λ =527 565 nm. Notably, exhibits properties,...