A5091612440- Polymer Surface Interaction Studies
- Quantum Dots Synthesis And Properties
- Electrospun Nanofibers in Biomedical Applications
- Marine Biology and Environmental Chemistry
- Electrocatalysts for Energy Conversion
- Surface Modification and Superhydrophobicity
- Chalcogenide Semiconductor Thin Films
- Advanced Sensor and Energy Harvesting Materials
- Fuel Cells and Related Materials
- Microbial Community Ecology and Physiology
- Advancements in Battery Materials
- Bone and Dental Protein Studies
- Bone Tissue Engineering Materials
- Listeria monocytogenes in Food Safety
- Advanced battery technologies research
- ZnO doping and properties
- Advanced Antenna and Metasurface Technologies
- Nanocluster Synthesis and Applications
- Cancer-related molecular mechanisms research
- Gas Sensing Nanomaterials and Sensors
- Collagen: Extraction and Characterization
- Genomics and Phylogenetic Studies
- Advanced Battery Technologies Research
- Conducting polymers and applications
- Folate and B Vitamins Research
Second Affiliated Hospital of Zhejiang University
2024-2025
Capital Institute of Pediatrics
2022-2025
Huashan Hospital
2025
Fudan University
2025
Chongqing University
2025
First Affiliated Hospital of Wenzhou Medical University
2024-2025
National Institute for Communicable Disease Control and Prevention
2023-2025
Stomatology Hospital
2025
Nanjing University
2024-2025
Wenzhou Medical University
2024-2025
We propose a design of an extremely broad frequency band absorber based on destructive interference mechanism. Metamaterial multilayered SRRs structure is used to realize desirable refractive index dispersion spectrum, which can induce successive anti-reflection in wide range. The corresponding high absorptance originates from the two reflection waves surfaces metamaterial. A strongly absorptive bandwidth almost 60 GHz demonstrated range 0 70 numerically. This provides effective and feasible...
Zwitterionic poly(sulfobetaine methacrylate) (PSBMA) has been well studied for its superhydrophilic and ultralow biofouling properties, making it a promising material superabsorbent nonadherent wound dressings. Electrospinning provides multiple desirable features dressings, including high absorptivity due to surface-area-to-volume ratio, gas permeation, conformability contour of the bed. The goal this work is develop fibrous membrane PSBMA via electrospinning evaluate properties related...
BACKGROUND: Whether it is effective and safe to extend the time window of intravenous thrombolysis up 24 hours after last known well unknown. We aimed determine efficacy safety tenecteplase in Chinese patients with acute ischemic stroke due large/medium vessel occlusion within an extended window. METHODS: Patients presenting 4.5 from well, a favorable penumbral profile associated occlusion, were randomized 1:1 either 0.25 mg/kg or best medical treatment. A was defined as hypoperfusion lesion...
The orientation of antibodies on surfaces is critical to the performance biosensors. Due charge distribution within an antibody molecule, it hoped that adsorbed can be controlled by adjusting microenvironments (e.g., surface and solution properties). In this work, we investigated orientations two types monoclonal anti-human chorionic gonadotropin (anti-hCG) NH2 (positively charged) COOH (negatively terminated self-assembled monolayers (SAMs) plasmon resonance (SPR) Adsorbed molecules were...
Oil-water separation is a major problem in industries such as oil production and wastewater treatment, where millions of gallons oil-contaminated water are produced. Zwitterionic poly(sulfobetaine methacrylate) (pSBMA) superhydrophilic polymer due to its strong interaction with via electrostatic interactions. By coating surfaces filter media polymer, it expected that one can effectively separate water. In this work, pSBMA was grafted onto glass fiber using surface-initiated atom transfer...
A serine-based zwitterionic poly(serine methacrylate) (pSerMA) was developed in this work to be used as a potential antifouling material. surface-initiated photoiniferter-mediated polymerization (SI-PIMP) method graft polymer brushes on gold surfaces. The pSerMA-grafted samples with different film thicknesses were readily prepared by varying the UV-irradiation time. With optimal thickness, adsorptions from bovine serum albumin, human serum, and plasma onto surfaces, evaluated surface plasmon...
New switchable hydrogels are developed. Under acidic conditions, undergo self-cyclization and can catch kill bacteria. neutral/basic ring-opening release killed bacterial cells resist protein adsorption attachment. Smart also show a dramatically improved mechanical property, which is highly desired for biomedical applications.
In this work, polyacrylamide is investigated as an ultralow fouling surface coating to highly resist protein adsorption, cell adhesion, and bacterial attachment. Polyacrylamide was grafted on gold surfaces via surface-initiated atom transfer radical polymerization (ATRP). Protein adsorption from a wide range of biological media, including single solutions fibrinogen, bovine serum albumin, lysozyme, dilute undiluted human blood serum, plasma, studied by plasmon resonance (SPR). Dependence the...
Arterial pulsation has been suggested as a key driver of paravascular cerebrospinal fluid flow, which is the foundation glymphatic clearance. However, whether intracranial arterial pulsatility associated with markers in humans not yet studied. Seventy-three community participants were enrolled study. 4D phase-contrast magnetic resonance imaging (MRI) was used to quantify hemodynamic parameters including flow index (PIflow) and area (PIarea) from 13 major intracerebral segments. Three...
Cell migration is essential to many physiological processes, including angiogenesis, which critical the success of implanted biomaterials and tissue-engineered constructs. Gradients play an important role in cell migration. Previous work on has been mostly executed either concentration gradients stimuli (e.g., VEGF) bulk or hydrogels surface-density ECM proteins fibronectin) small ligands RGD). Little done investigate how responds growth factors. No study surface both adhesive factors...
Zwitterionic hydrogels, including poly(sulfobetaine methacrylate) (polySBMA) and poly(carboxybetaine (polyCBMA), co-polymeric hydrogels of CBMA 2-hydroxyethyl methacrylate (HEMA) (poly(CBMA-co-HEMA)) were prepared. Their in vitro vivo properties evaluated compared with those polyHEMA hydrogels. Bovine aortic endothelial cells (BAECs) incubated zwitterionic to evaluate their bioadhesion properties. Both polySBMA polyCBMA found be non-cytotoxic endotoxin levels acceptable for implantation....
The misfolding and aggregation of β-amyloid peptides (Aβ) into amyloid fibrils, a process that has been pathologically linked to the onset Alzheimer's disease, is dependent on presence heterogeneous surface (e.g., cell membrane). Understanding kinetics fibril formation associated structural transition from monomers intermediates eventually fibrils critical for development viable therapeutic agents. In this work, using circular dichroism (CD), atomic force microscopy (AFM), plasmon resonance...
A new type of polymer highly resistant to nonspecific protein adsorption is reported. Poly(N-methyl-β-alanine) (PMeA) and poly(N-ethyl-β-alanine) (PEtA) synthesized via cobalt-catalyzed carbonylative polymerization N-methylaziridine N-ethylaziridine were end-functionalized with thiol groups grafted onto Au surfaces. Protein was studied by the surface plasmon resonance (SPR) method. The amounts representative single proteins adsorbed PMeA- PEtA-grafted surfaces below detection limit SPR at...
We aimed to comprehensively explore the etiology of granulomatous lobular mastitis (GLM) optimize treatment programs.We collected 30 fresh samples for metagenomic next-generation sequencing, morphological observation, and analysis clinical information.Of samples, 25 were GLM; pathogens detected in 17, these were: Corynebacterium kroppenstedtii (10 25, 40%); C. Pseudomonas oleovorans (3 12%); human gammaherpesvirus 4 (1 4%); Acinetobacter baumannii P. Tepidiphilus thermophilus 4%). Abnormal...
In this work, we demonstrate the strong resistance of oligo(phosphorylcholine) (OPC) self-assembled monolayers (SAMs) to protein adsorption and cell adhesion. OPC SAMs were characterized using X-ray photoelectron spectroscopy (XPS), was measured a surface plasmon resonance (SPR) sensor. Results are compared with those phosphorylcholine (PC) SAMs. Despite existence negative charge on simple synthesis procedure thiols, resist as effectively or better than PC formed from highly purified thiols....
Abstract A well‐controlled biocompatible nonfouling surface is significant for biomedical requirements, especially the improvement of biocompatibility. We demonstrate low or nonbiofouling surfaces by coating hydrophobic–hydrophilic triblock copolymers poly(ethylene oxide)‐poly(propylene oxide)‐poly(ethylene oxide) (PEO‐PPO‐PEO) on CH 3 ‐terminated self‐assembled monolayer (SAM). Two types are used to modify surface, one with different PEO/PPO ratios (∼20/80, 40/60, and 80/20, w/w) but same...