A5006167280- Prostate Cancer Diagnosis and Treatment
- MRI in cancer diagnosis
- Advanced MRI Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Prostate Cancer Treatment and Research
- Urologic and reproductive health conditions
- Advanced Neural Network Applications
- Medical Image Segmentation Techniques
- Advanced Neuroimaging Techniques and Applications
- AI in cancer detection
- Urological Disorders and Treatments
- Urinary Bladder and Prostate Research
- Ultrasound and Hyperthermia Applications
- Medical Imaging Techniques and Applications
- Generative Adversarial Networks and Image Synthesis
- Medical Imaging and Analysis
- Advanced X-ray and CT Imaging
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Blind Source Separation Techniques
- Systemic Lupus Erythematosus Research
- Pelvic floor disorders treatments
- Ectopic Pregnancy Diagnosis and Management
- Gallbladder and Bile Duct Disorders
- Ultrasound Imaging and Elastography
- Hormonal and reproductive studies
University of Chicago
2016-2025
University Radiology
2018
Beijing Jiaotong University
2016
Aga Khan University
2010
Magnetic resonance imaging guided focal laser ablation is an investigational strategy for the treatment of prostate cancer.This phase II evaluation included men with stage T1c-T2a, specific antigen less than 15 ng/ml or density 0.15 ng/ml3, Gleason 7 in 25% biopsies and magnetic 1 2 lesions concordant biopsy detected cancer. At 3 months all patients underwent zone(s). 12 systematic biopsy. I-PSS (International Prostate Symptom Score) SHIM (Sexual Health Inventory Men) scores were collected...
Comparison of T2-Weighted Imaging, DWI, and Dynamic Contrast-Enhanced MRI for Calculation Prostate Cancer Index Lesion Volume: Correlation With Whole-Mount PathologyChongpeng Sun1,2, Aritrick Chatterjee1, Ambereen Yousuf1, Tatjana Antic3, Scott Eggener4, Gregory S. Karczmar1 Aytekin Oto1Audio Available | Share Claim CREDIT
This study demonstrates that hybrid multidimensional MRI has the potential to improve MRI/US fusion biopsy results, provide more reliable detection of prostate cancer, and add complementary information Prostate Imaging Reporting Data System–based evaluation by expert radiologists.
Extracting the high-level feature representation by using deep neural networks for detection of prostate cancer, and then based on constructing hierarchical classification to refine results.High-level is first learned a learning network, where multiparametric MR images are used as input data. Then, features, method developed, multiple random forest classifiers iteratively constructed results cancer.The experiments were carried 21 real patient subjects, proposed achieves an averaged...
To study the dependence of apparent diffusion coefficient (ADC) and T2 on echo time (TE) b-value, respectively, in normal prostate cancer, using two-dimensional MRI sampling, referred to as "hybrid multidimensional imaging."The included 10 patients with biopsy-proven cancer who underwent 3 Tesla MRI. Diffusion-weighted (DWI) data were acquired at b = 0, 750, 1500 s/mm(2) . For each TEs 47, 75, 100 ms. ADC measured a function b-value TE, 15 regions interest (ROIs). The Friedman test was used...
Benign prostatic hyperplasia (BPH) is a common condition in middle-aged and older men negatively affects the quality of life. An ultrasound classification for BPH based on previous pathologic was reported, types were classified according to different enlargement locations prostate. Afterwards, this demonstrated using magnetic resonance imaging (MRI). The important, as patients with can have symptoms treatment options. MRI are follows: type 0, an equal or less than 25 cm3 prostate showing...
Background Tissue estimates obtained by using microstructure imaging techniques, such as hybrid multidimensional (HM) MRI, may improve prostate cancer diagnosis but require histologic validation. Purpose To validate tissue composition measured HM with quantitative evaluation from whole-mount prostatectomy the reference standard. Materials and Methods In this HIPAA-compliant study, December 2016 to July 2018, prospective participants biopsy-confirmed underwent 3-T MRI before radical...
Background Variability of acquisition and interpretation prostate multiparametric MRI (mpMRI) persists despite implementation the Prostate Imaging Reporting Data System (PI-RADS) version 2.1 due to range reader experience subjectivity lesion characterization. A quantitative method, hybrid multidimensional (HM-MRI), may introduce objectivity. Purpose To compare performance, interobserver agreement, time radiologists using mpMRI versus HM-MRI diagnose clinically significant cancer. Materials...
To determine the possibility of obtaining high-quality magnetic resonance (MR) images before, during, and immediately after ejaculation detecting measurable changes in quantitative MR imaging parameters ejaculation.In this prospective, institutional review board-approved, HIPAA-compliant study, eight young healthy volunteers (median age, 22.5 years), providing informed consent, underwent while masturbating to point ejaculation. A 1.5-T unit was used, with an eight-channel surface coil a...
Purpose To investigate the correlation between magnetic resonance imaging (MRI)‐derived prostate parameters and benign prostatic hyperplasia (BPH) type with International Prostate Symptom Score (IPSS). Materials Methods In all, 61 patients (median age, 60; range, 41–81 years) who underwent preoperative MRI prostatectomy were included in this retrospective study. The MRI‐based including total volume (TPV), transition zone (TZ) (TZV), TZ index, intravesical protrusion (IPP), anterior...
The purpose of this article is to study relationships between MRI-based prostate volume and volume-adjusted serum prostate-specific antigen (PSA) concentration estimates cancer Gleason score.The included 61 patients with (average age, 63.3 years; range 52-75 years) who underwent MRI before prostatectomy. A semiautomated technique was used estimate total central gland volumes, fraction (central divided by volume), PSA density (PSAD; PSAD for the (PSA volume). These were compared prostatectomy...
The objective of our study was to evaluate the role a hybrid T2-weighted imaging-DWI sequence for prostate cancer diagnosis and differentiation aggressive from nonaggressive cancer.Twenty-one patients with who underwent preoperative 3-T MRI prostatectomy were included in this study. Patients examination consisting DW images acquired TEs 47, 75, 100 ms b values 0 750 s/mm(2). apparent diffusion coefficient (ADC) T2 calculated normal ROIs at each TE value. Changes ADC as function increasing...
The purpose of this study was to evaluate the effect increasing spatial resolution prostate DWI protocol on image quality and lesion conspicuity.Twenty-nine patients with biopsy-proven cancer undergoing MRI examinations were imaged two diffusion-weighted imaging (DWI) protocols: current standard clinical (6.7 mm(3) voxels) a new high-resolution (3.1 voxels). Diffusion-weighted images independently subjectively scored conspicuity, internal architecture definition, overall by radiologists....
The purpose of this study is to describe the quantitative and qualitative findings multiparametric prostate MRI performed after MRI-guided focal laser ablation cancer.A total 27 consenting patients met inclusion criteria, which included but were not limited presence clinical category T1c-T2a cancer with a Gleason score 7 or less, having undergone biopsy before ablation, immediately 3 12 months ablation. Signal changes evaluated both qualitatively quantitatively then correlated results...
Multiparametric MRI Features and Pathologic Outcome of Wedge-Shaped Lesions in the Peripheral Zone on T2-Weighted Images ProstateAritrick Chatterjee1, Sevil Tokdemir2, Alexander J. Gallan3, Ambereen Yousuf1, Tatjana Antic3, Gregory S. Karczmar1 Aytekin Oto1Audio Available | Share
This study investigates whether administration of low doses gadolinium-based contrast agent (GBCA) for dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) can be as effective a standard dose in distinguishing prostate cancer (PCa) from benign tissue. In addition, we evaluated the combination kinetic parameters low- and high-dose injection new diagnostic marker.Patients (n = 17) with histologically confirmed PCa underwent preoperative 3 T MRI. Dynamic MRI images were acquired at...