A5047795251- Menstrual Health and Disorders
- Pregnancy-related medical research
- Pregnancy and preeclampsia studies
- Maternal and fetal healthcare
- Birth, Development, and Health
- Surgical Sutures and Adhesives
- Biochemical effects in animals
- Spine and Intervertebral Disc Pathology
- Prenatal Screening and Diagnostics
- Epigenetics and DNA Methylation
- Musculoskeletal pain and rehabilitation
- Anorectal Disease Treatments and Outcomes
- Parvovirus B19 Infection Studies
- Prenatal Substance Exposure Effects
- Pelvic floor disorders treatments
- Gestational Diabetes Research and Management
- Preterm Birth and Chorioamnionitis
- Cardiovascular Issues in Pregnancy
- Healthcare and Venom Research
- Maternal Mental Health During Pregnancy and Postpartum
- Delphi Technique in Research
- Autism Spectrum Disorder Research
- Dermatological and COVID-19 studies
- Pelvic and Acetabular Injuries
- Folate and B Vitamins Research
Mayo Clinic in Arizona
2024
University of Kirkuk
2023
Al-Qalam University College
2023
University of Minnesota
2023
University of Minnesota Medical Center
2022
Aswan University
2020
University of Malaya
2010-2019
Keele University
2003-2018
University of Birmingham
2012-2017
Birmingham Women's Hospital
2000-2016
Supplementation with folic acid during pregnancy is known to reduce the risk of neural tube defects and low birth weight. It thought that folate other one-carbon intermediates might secure these clinical effects via DNA methylation. We examined on human methylome using quantitative interrogation 27,578 CpG loci associated 14,496 genes at single-nucleotide resolution across 12 fetal cord blood samples. Consistent previous studies, majority dinucleotides located within islands exhibited...
In patients with sarcoidosis suspected cardiac involvement, late gadolinium enhancement (LGE) on cardiovascular magnetic resonance imaging (CMR) identifies those an increased risk of adverse outcomes. However, these outcomes are experienced by only a minority LGE, and identifying this subgroup may improve treatment in patients.To assess whether CMR phenotypes based left ventricular ejection fraction (LVEF) LGE (CS) associated during follow-up.This cohort study included consecutive...
Folic acid supplementation during pregnancy has known beneficial effects. It reduces risk of neural tube defects and low birth weight. Folate other one-carbon intermediates might secure these clinical effects via DNA methylation. However, most data on the folate epigenome is derived from animal or in vitro models. We examined relationship between cord blood methylation maternal folic intake, homocysteine using 24 pregnant women. Genome-wide was determined by level LINE-1 repeats...
BACKGROUND: Randomized trials in obstructive coronary artery disease (CAD) have largely shown no prognostic benefit from revascularization. Although there are several potential reasons for the lack of benefit, an underexplored possible reason is presence coincidental nonischemic cardiomyopathy (NICM). We investigated prevalence and significance NICM patients with CAD (CAD-NICM). METHODS: conducted a registry study consecutive on angiography who underwent contrast-enhanced cardiovascular...
Objectives : To identify the etiology and pregnancy outcome of hydrops fetalis in a cohort pregnancies referred to tertiary maternal fetal medicine center UK. These data allow review large series affected by emphasize importance investigation then treatment individual cases. This provides parents with improved information especially specific prognostic information. Methods A retrospective 63 consecutive cases managed between September 1996 March 1999. Results Of pregnancies, 12.7% ( n = 8)...
To identify the etiology and pregnancy outcome of hydrops fetalis in a cohort pregnancies referred to tertiary maternal fetal medicine center UK. These data allow review large series affected by emphasize importance investigation then treatment individual cases. This provides parents with improved information especially specific prognostic information.A retrospective 63 consecutive cases managed between September 1996 March 1999.Of pregnancies, 12.7% (n = 8) were associated an 'immune'...
Background Many pregnant women experience low back pain. Acupuncture appears to be a safe, promising intervention but evidence is needed about its clinical effectiveness and cost-effectiveness. Objectives To assess the feasibility of future large randomised controlled trial (RCT) testing additional benefit adding acupuncture standard care (SC) for pregnancy-related Design Phase 1: questionnaire survey described current Focus groups interviews with midwives, physiotherapists explored...
Background The prognosis of early-onset pre-eclampsia (before 34 weeks’ gestation) is variable. Accurate prediction complications required to plan appropriate management in high-risk women. Objective To develop and validate models for outcomes pre-eclampsia. Design Prospective cohort model development, with validation two external data sets. Setting Model development: 53 obstetric units the UK. transportability: PIERS (Pre-eclampsia Integrated Estimate RiSk mothers) PETRA (Pre-Eclampsia...
In Brief OBJECTIVE: To assess whether the G allele of serotonin receptor 1A C(-1019)G polymorphism is associated with premenstrual dysphoric disorder. METHODS: The study sample comprised 53 women clinically diagnosed disorder (age range 27–46 years, mean 37.7 years) and 51 healthy control subjects 22–48 36.2 years). was genotyped compared between two groups. RESULTS: contrast to postulated "high-risk" G/G genotype, there a marked overrepresentation C/C genotype in group (P=.034; odds ratio...