- Cardiovascular Function and Risk Factors
- Acute Myocardial Infarction Research
- Cardiovascular Disease and Adiposity
- Cardiac electrophysiology and arrhythmias
- Cardiac Imaging and Diagnostics
- Inflammatory Biomarkers in Disease Prognosis
- Cardiac Arrhythmias and Treatments
- Cardiovascular Health and Disease Prevention
- Atrial Fibrillation Management and Outcomes
- Heart Failure Treatment and Management
- Venous Thromboembolism Diagnosis and Management
- Adipokines, Inflammation, and Metabolic Diseases
- Cardiac pacing and defibrillation studies
- ECG Monitoring and Analysis
- Coronary Artery Anomalies
- Cardiac Valve Diseases and Treatments
- Cardiac Structural Anomalies and Repair
- Liver Disease Diagnosis and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Pregnancy and preeclampsia studies
- Congenital Heart Disease Studies
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Heart Rate Variability and Autonomic Control
- Cardiac Health and Mental Health
- Antiplatelet Therapy and Cardiovascular Diseases
Çanakkale Onsekiz Mart Üniversitesi
2013-2024
İstanbul Eğitim ve Araştırma Hastanesi
2021
Institute of Cardiology
2021
Canakkale Onsekiz Mart Universitesi Tip Fakultesi Hastanesi
2013-2014
Background:Platelet-to-lymphocyte ratio (PLR) is a new prognostic marker in coronary artery disease. We aimed to evaluate the relationship between PLR and in-hospital mortality patients with ST-elevated acute myocardial infarction (AMI). Material andMethods:The present study included 636 AMI. The population was divided into tertiles based on their admission PLR. Patients having values third tertile defined as high group (n=212) those lower 2 were low (n=424). Results:Risk factors of disease...
The predictive value of leukocyte counts has been reported in patients with acute myocardial infarction (AMI). We aimed to evaluate the total count and neutrophil-lymphocyte (N/L) ratio for mortality due AMI. A 522 ST-elevated MI were included study. study population was divided into tertiles based on admission N/L values. High (n = 174) low 348) groups defined as having values third tertile (>5.77) lower 2 (≤ 5.77), respectively. high group had a significantly higher incidence in-hospital...
Platelet activation plays a pivotal role in acute coronary syndrome (ACS). We investigated the relationship between platelet distribution width (PDW) and severity of artery disease (CAD) patients with ACS. A total 502 ACS were enrolled. High (n = 151) low PDW 351) groups defined as having values third tertile (>17%) lower 2 tertiles (≤17%). There significantly higher Gensini score (44 [10-168] vs. 36 [2-132], P < .001), neutrophil-lymphocyte ratio (3.1 [0.8-12.4] .2.5 [0.3-13], .012)...
Aim. Cardiac troponins are the most preferred biomarkers in evaluation of acute coronary syndromes (ACS). The aim our study was to examine association between high sensitive troponin T (hs-TnT), and neutrophil lymphocyte ratio (NLR) complexity ACS assessed by SYNTAX Score. Methods results. 287 patients who underwent angiography were studied (215 male, mean age 62.0 ± 12.7 years). 133 ST elevation myocardial infarction (STEMI), 154 non-ST (NSTE) . divided tertiles according Score; Score ≤ 22...
The albumin to globulin ratio (AGR) is used as a prognostic marker in acute ischemic cardiovascular events. We investigated whether serum AGR, fibrinogen, and fibrinogen (FAR) are related the presence severity of coronary artery disease (CAD). Patients who underwent angiography procedures were analyzed retrospectively. CAD was assessed by Gensini score. study population (3031 patients; 1071 females 1960 males) divided into 3 tertiles based on AGR values. score, lipid levels, diabetes...
The prognostic value of the Global Registry Acute Coronary Events (GRACE) risk score (GRS) and Thrombolysis In Myocardial Infarction (TIMI) index (TRI) has been reported in coronary artery disease (CAD) patients. We aimed to evaluate relationship between GRS, TRI, severity CAD evaluated by SYNTAX (SS) patients with acute syndrome (ACS).Patients ACS who were admitted care unit our institution retrospectively this study. A total 287 [154 non-ST elevated (NSTE-ACS), 133 ST myocardial infarction...
Background: Fragmented QRS (fQRS) complexes on 12-lead electrocardiography (ECG) have been reported to be predictors of cardiac events and all-cause mortality in coronary artery disease (CAD). Aim: To investigate the relationship between fQRS SYNTAX Gensini scores patients with acute syndrome (ACS). Methods: A total 302 (223 men 79 women) ACS (133 ST elevated myocardial infarction [STEMI], 107 non-STEMI [NSTEMI], 62 unstable angina pectoris [USAP]) were evaluated retrospectively this study....
Red cell distribution width (RDW) has been reported to be a predictor of cardiac events in coronary artery disease (CAD). Here, we hypothesized that RDW level on admission would predictive adverse outcomes non-ST elevation acute syndrome (NST-ACS).In total, 202 patients with NST-ACS (159 males and 43 females) were retrospectively analyzed. The divided into two groups based the 50th percentile levels. A high group (n=100) was defined as those having levels >14.0. relationship between primary...
Aim Hemodialysis ( HD ) patients had higher cardiovascular mortality and it is related to atherosclerosis. Epicardial adipose tissue EAT thickness a marker of atherosclerosis independent predictor coronary artery disease. The aim our study was evaluate the relationship between carotid intima‐media CIMT predictors early in patients. Methods included 62 40 healthy controls. were measured by echocardiography all subjects. Results (6.98 ± 1.67 vs. 3.84 0.73 mm, P < 0.001, 0.94 0.17 0.63 0.11...
The prognostic value of a high platelet-lymphocyte ratio (PLR) has been reported in patients with non-ST elevated myocardial infarction (NSTEMI) and different oncologic disorders. We aimed to evaluate the predictive PLR for left ventricular systolic dysfunction (LVSD) acute coronary syndrome (NST-ACS).A total 220 NST-ACS were included study. study population was divided into tertiles based on admission values. High (n=73) low (n=147) groups defined as having values third tertile (>135.6)...
<b><i>Objective:</i></b> While severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) primarily affects lung tissue, it may cause direct or indirect damage to the cardiovascular system, and permanent occur. Arterial stiffness is an early indicator of disease risk. The aim our study was establish potential effects SARS-CoV-2 on vascular system evaluated by transthoracic echocardiographic examination. <b><i>Subjects Methods:</i></b> This...
Ventricular ectopic beats (VEBs) are usually considered a benign condition that can be managed with conservative measures. Heart rate variability (HRV), which is one of the most important methods for assessing autonomic activity, noninvasive, quantitative method analyzing effects on heart. We aimed to investigate risk arrhythmia in patients VEBs and without cardiovascular disease by using HRV parameters.Patients frequent (more than 30 times 1 hour, according Lown classification) were...
Objective: We aimed to study the predictive value of neutrophil-lymphocyte ratio (NLR) for left ventricular systolic dysfunction (LVSD) in patients with non ST-elevated acute coronary syndrome (NST-ACS).Methods: A total 405 (mean age 62 years and 75% male) NST-ACS were included study. The population was divided into tertiles based on admission NLR values. low, medium high defined as NLR≤1.81 (n=135), 1.81<NLR≤3.2 (n=135) NLR>3.2 respectively.Results: group older (p<0.001), have higher rate...
In this study, we aimed to analyze the TURKMI registry identify factors associated with delays from symptom onset treatment that would be focus of improvement efforts in patients acute myocardial infarction (AMI) Turkey.The study is a nation-wide was conducted 50 centers capable 24/7 primary percutaneous coronary intervention (PCI). All consecutive (n=1930) AMI admitted care units within 48 hours were prospectively enrolled during predefined 2-week period between November 1, 2018, and 16,...
Aim The aim of our study was, echocardiographic epicardial adipose tissue ( EAT ) thickness could show the severity and prognosis acute coronary syndromes ACS ). Methods Results Sixty‐five patients (mean age 57.4 ± 12.2 years) who underwent angiography were studied. on free wall right ventricle was measured at end‐diastole from parasternal long‐axis views 3 cardiac cycles. SYNTAX Global Registry Acute Coronary Events (GRACE) scoring considered for . mean value 5.5 0.5 mm (range 1–12 mm). had...
<b><i>Objective:</i></b> To investigate intercellular adhesion molecule-1 <i>(ICAM1)</i> and angiotensinogen <i>(AGT)</i> gene polymorphisms, as related to atherosclerosis endothelial dysfunction, in coronary slow flow (CSF). <b><i>Subjects Methods:</i></b> The participants this study were 48 patients with CSF 67 normal controls. K469E polymorphism of <i>ICAM1</i> (rs5498) the T207M <i>AGT</i>...
Fragmented QRS (fQRS) as a predictor of cardiac events in coronary artery disease has previously been reported. In this study, we hypothesized that presence fQRS on 12-lead electrocardiogram (ECG) admission would be predictive adverse outcomes non-ST elevated myocardial infarction (NSTEMI).A total 149 NSTEMI patients (112 male, 37 female) were retrospectively analyzed. The pattern was defined the an additional R', notching nadir S wave, fragmentation RS or QS complexes 2 contiguous leads...
Objectives Patients with inflammatory bowel disease (IBD) have high cardiovascular morbidity, and, in general, epicardial adipose tissue thickness is related to atherosclerotic vascular disease. This study aimed investigate the association between and carotid intima‐media as markers of early atherosclerosis patients IBD. Methods The comprised 47 IBD (25 Crohn 22 ulcerative colitis) 35 control participants. In all individuals, values were measured by sonography. Results mean age ± SD was 42.3...
Background:We examined the effects of ACE, PAI-1 and eNOS gene polymorphisms on endothelial function.The genes are related to atherosclerosis dysfunction in coronary slow flow (CSF).Methods: Thirty-three patients with angiographically proven CSF 48 subjects normal were enrolled this study.Coronary patterns determined by thrombolysis myocardial infarction (TIMI) frame count method.Endothelial function was assessed brachial artery endothelium-dependent flow-mediated dilatation (FMD).PAI-1...
In this study, we aimed to demonstrate whether the presence of fragmented QRS (fQRS) is associated with frequency premature ventricular contractions (PVCs).We retrospectively analyzed 282 cases by 24-hour Holter monitorings (HMs) between August 2012 and February 2013. Firstly, patients were divided into 2 groups respect fQRS then 3 PVCs as Group 1: seldom PVC (<120 PVCs/day), 2: moderate-frequency (120-720 3: frequent (>720 PVCs/day). We investigated predictors using multinomial logistic...
Objective: Prior studies have demonstrated the relationship between cardiovascular diseases and fragmented QRS (fQRS). fQRS was also associated with ventricular arrhythmias. Our objective to find out paroxysmal atrial fibrillation (PAF).Method: A total of 301 patients without overt structural heart disease were prospectively included in study. Patients divided 2 groups according presence fQRS. Multivariate logistic regression analysis used assess predictive value for predicting PAF.Results:...
Despite advances in therapeutic management of patients with heart failure, there is still an increasing morbidity and mortality all over the world. In this study, we aimed to present 3-year follow-up outcomes included Journey HF-TR study 2016 that has evaluated clinical characteristics acute failure admitted hospital a national registry data.The was designed retrospectively between November December 2019. Patient data previously published were used. Among 1606 patients, 1484 due dropout 122...