- Meta-analysis and systematic reviews
- Anesthesia and Pain Management
- Musculoskeletal pain and rehabilitation
- Infant Nutrition and Health
- Bone fractures and treatments
- Cannabis and Cannabinoid Research
- COVID-19 and healthcare impacts
- Infant Development and Preterm Care
- Neonatal Respiratory Health Research
- Opioid Use Disorder Treatment
- Total Knee Arthroplasty Outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Pediatric Pain Management Techniques
- Technology Adoption and User Behaviour
- COVID-19 and Mental Health
- Parathyroid Disorders and Treatments
- Long-Term Effects of COVID-19
- Pain Mechanisms and Treatments
- HIV/AIDS Research and Interventions
- Cardiac, Anesthesia and Surgical Outcomes
- Delphi Technique in Research
- Pain Management and Opioid Use
- Health Policy Implementation Science
- Surgical site infection prevention
- Ethics in Clinical Research
McMaster University
2015-2023
Impact
2017-2023
Chinese Culture University
2022-2023
Hebei Science and Technology Department
2023
Hebei Medical University
2023
Huazhong University of Science and Technology
2022
London South Bank University
2021
Centre for Disability Prevention and Rehabilitation
2021
National Defense Medical Center
2020
Tri-Service General Hospital
2020
Abstract Background: Older adults with acute myeloid leukemia (AML) represent a vulnerable population in whom disease-based and clinical risk factors, patient goals, prognosis, practitioner- patient-perceived treatment risks benefits influence recommendations. Objective: These evidence-based guidelines of the American Society Hematology (ASH) are intended to support patients, clinicians, other health care professionals their decisions about management AML older adults. Methods: ASH formed...
"If anything kills over 10 million people in the next few decades, it's most likely to be a highly infectious virus, rather than war. Not missiles, but microbes. Now, part of this reason is that we've invested huge amount nuclear deterrents, actually very little system stop an epidemic. We're not ready for epidemic." —Bill Gates, TEDx, Vancouver, British Columbia, Canada, 2015 The outbreak novel coronavirus, referred as severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) or...
The NLRP3 inflammasome is a caspase-1-containing multi-protein complex that controls the release of IL-1β and plays important roles in development inflammatory disease. Here, we report resveratrol, polyphenolic compound naturally produced by plants, inhibits inflammasome-derived secretion pyroptosis macrophages. Resveratrol activation step suppressing mitochondrial damage. also induces autophagy activating p38, macrophages treated with an inhibitor are resistant to suppressive effects...
<b>Objective</b> To determine the frequency of survival, stroke, atrial fibrillation, structural valve deterioration, and length hospital stay after surgical replacement an aortic (SAVR) with a bioprosthetic in patients severe symptomatic stenosis. <b>Design</b> Systematic review meta-analysis observational studies. <b>Data sources</b> Medline, Embase, PubMed (non-Medline records only), Cochrane Database Systematic Reviews, CENTRAL from 2002 to June 2016. <b>Study...
<b>Objective</b> To examine the effect of transcatheter aortic valve implantation (TAVI) versus surgical replacement an (SAVR) in patients with severe stenosis at low and intermediate risk perioperative death. <b>Design</b> Systematic review meta-analysis <b>Data sources</b> Medline, Embase, Cochrane CENTRAL. <b>Study selection</b> Randomized trials TAVI compared SAVR a mean death <8%. <b>Review methods</b> Two reviewers independently extracted data assessed bias...
Modulation of intestinal microbiome by administering probiotics, prebiotics, or both may prevent morbidity and mortality in premature infants.