A5100748619- Herpesvirus Infections and Treatments
- Plant Parasitism and Resistance
- Plant Pathogenic Bacteria Studies
- Single-cell and spatial transcriptomics
- Immune cells in cancer
- Cytomegalovirus and herpesvirus research
- CRISPR and Genetic Engineering
- Virus-based gene therapy research
- Plant-Microbe Interactions and Immunity
Institute of Plant Protection
2024
Chinese Academy of Agricultural Sciences
2024
Hainan University
2022-2024
Two guanine base editors created using an engineered N-methylpurine DNA glycosylase with CRISPR systems achieved targeted G-to-T editing 4.94–12.50% efficiency in rice (Oryza sativa). The combined use of the and deaminases enabled co-editing target guanines adenines or cytosines. Single nucleotide polymorphisms (SNPs) are widely present related to desirable agronomic traits crops. clustered regularly interspaced palindromic repeats (CRISPR)/CRISPR-associated nuclease 9 (Cas9)-mediated have...
Abstract Recent advancements of sequencing-based spatial transcriptomics (sST) have catalyzed significant by facilitating transcriptome-scale gene expression measurement. Despite this progress, efforts to comprehensively benchmark different platforms are currently lacking. The extant variability across technologies and datasets poses challenges in formulating standardized evaluation metrics. In study, we established a collection reference tissues regions characterized well-defined...
Powdery mildew severely affects several important crops and cash plants. Disruption of resistance locus O (MLO) genes elevates against powdery in However, whether rubber tree (Heveae brasiliensis) MLO proteins are linked to susceptibility remains unknown, owing technical limitations the genetic manipulation this woody plant. A previous study showed that H. brasiliensis MLO-like protein HbMLO12 demonstrates high amino acid sequence similarity with known Arabidopsis AtMLO12. In study, we...