A5084774033- Metal complexes synthesis and properties
- Synthesis and biological activity
- Synthesis and Characterization of Heterocyclic Compounds
- Inorganic and Organometallic Chemistry
- Plant biochemistry and biosynthesis
- Multicomponent Synthesis of Heterocycles
- Microbial Natural Products and Biosynthesis
- Water Quality and Pollution Assessment
- Plant-based Medicinal Research
- Chromium effects and bioremediation
- Synthesis and Catalytic Reactions
- Phenothiazines and Benzothiazines Synthesis and Activities
- Synthesis of β-Lactam Compounds
- Metal-Organic Frameworks: Synthesis and Applications
- Phytochemistry and Biological Activities
- Analytical Chemistry and Chromatography
- Chemical Thermodynamics and Molecular Structure
- Plant-derived Lignans Synthesis and Bioactivity
- Cyclopropane Reaction Mechanisms
- Adsorption and biosorption for pollutant removal
- Berberine and alkaloids research
- Free Radicals and Antioxidants
- Plant Pathogenic Bacteria Studies
- Bioactive Natural Diterpenoids Research
- Lipid Membrane Structure and Behavior
Chiba University
2017-2025
University of Illinois Urbana-Champaign
2025
Al-Zahra College for Women
2016-2024
Babasaheb Bhimrao Ambedkar Bihar University
2023
Ashoka University
2023
University of Southampton
2019-2022
National University of Singapore
2016-2019
Banaras Hindu University
2016
Indian Institute of Technology BHU
2016
The present work reported the adsorption of Cr (VI) from aqueous solutions on activated carbon prepared mango kernel, a seasonal waste fruits. Kernels dried fruit shells were taken out and pulverized in micro-pulverizing mill. powder thus obtained was with 40% H3PO4 carbonized at 600 °C for 1 hour an inert atmosphere. Physico-chemical characteristics such as elemental composition, surface area, functional groups morphology analyzed using analyzer, BET area FTIR spectroscopy SEM analysis...
Abstract Plant genomes remain highly fragmented and are often characterized by hundreds to thousands of assembly gaps. Here, we report chromosome-level reference phased genome Ophiorrhiza pumila , a camptothecin-producing medicinal plant, through an ordered multi-scaffolding experimental validation approach. With 21 gaps contig N50 18.49 Mb, is one the most complete plant assembled date. We also 273 nitrogen-containing metabolites, including diverse monoterpene indole alkaloids (MIAs). A...
Aconitum carmichaelii is an important medicinal herb used widely in China, Japan, India, Korea, and other Asian countries. While extensive research on the characterization of metabolic extracts A. has shown accumulation numerous bioactive metabolites including aconitine aconitine-type diterpene alkaloids, its biosynthetic pathway remains largely unknown. Biosynthesis these secondary tightly controlled mostly occurs a tissue-specific manner; therefore, transcriptome analysis across multiple...
Secondary metabolites play a key role in coordinating ecology and defense strategies of plants. Diversity these arises by conjugation core structures with diverse chemical moieties, such as sugars glycosylation. Active pools phytohormones, including those involved plant stress response, are also regulated While much is known about the enzymes glycosylation, we know little their regulation or coordination other processes. We characterized flavonoid pathway transcription factor TRANSPARENT...
The current study is focused on using tannery waste called buffing dust to remove hexavalent chromium from an aqueous solution. was characterised by different technique like FTIR, SEM, and BET analysis. adsorption experiment conducted in batch mode. operating factors including contact time, dose initial Cr (VI) concentration were investigated. optimum capacity observed at time of 240 min 1g/100 mL. isotherm such as Langmuir, Freundlich Temkin investigated concentration. It that Langmuir...
Lithospermum officinale is a valuable source of bioactive metabolites with medicinal and industrial values. However, little known about genes involved in the biosynthesis these metabolites, primarily due to lack genome or transcriptome resources. This study presents first effort establish characterize de novo assembly resource for L. expression analysis three its tissues, namely leaf, stem, root. Using over 4Gbps RNA-sequencing datasets, we obtained officinale, consisting 77,047 unigenes N50...
Magnolia obovata is renowned for its unique bioactive constituents with medicinal properties traditionally used to treat digestive disorders, anxiety, and respiratory conditions. This study aimed establish a comprehensive omics resource through untargeted metabolome transcriptome profiling explore biosynthesis of pharmacologically active compounds M. using seven tissues: young leaf, mature stem, bark, central cylinder, floral bud, pistil. Untargeted metabolomic analysis identified 6733 mass...
Abstract Aconitum japonicum , native to the mountainous regions of Japan, is a toxic perennial plant widely recognized for its therapeutic potential. Despite pharmacological importance, complete biosynthetic pathway diterpene alkaloids, bioactive compounds with significant pharmaceutical implications and derived from species, remains elusive. In this study, leveraging high-throughput metabolome transcriptome analyses, we conducted comprehensive investigation using four tissues A. including...
Iron deficiency (ID) is the most widespread dietary concern globally, with females disproportionately affected due to physiological variables such as menstruation, pregnancy, and aging. The effects of iron on cognitive function in three female age groups—adolescents, mature individuals, elderly—are compared this study. It investigates neurodevelopment, brain functioning, age-associated decline using recent research. findings indicate that adolescents are especially susceptible long-term...
The Isoniazid (INH) ring system is one of the most important heterocycles in nature, as it represents an structural motif many biological compounds. It possesses significant antibacterial activity and given combination with Rifampicin, ethambutol, or pyrazinamide. There is, therefore, urgent need to design rapid, efficient, environmentally benign protocols for synthesis metal complexation INH-based moiety improve its stability bioactivity. Herein, we have developed a novel tetradentate INH...
Abstract A highly efficient, eco‐friendly, recyclable heterogeneous ZnFe 2 O 4 nanocatalyzed synthesis of 2‐amino‐4‐substituted 1,4‐dihydrobenzo[4,5]imidazo[1,2‐a]pyrimidine‐3‐carbonitrile (4a‐j) derivatives via one pot multicomponent reaction benzimidazole ( 1 ), substituted aromatic aldehyde 2a‐j ) and malononitrile 3 under ultrasonic irradiations. Significance this synthetic approach is short time, easy handling, simplicity, efficiency, high yield, recoverable catalyst.
The present study aims to determine the concentrations of potassium (K), sodium (Na), and soil pH in samples collected from Vaijapur tehsil region. Fertilizer-derived elements leached deposits have accumulated soil, contributing pollution. focus this research is compare nutrient content barren Cotton field area using flame photometry analysis.
A high-quality genome assembly is imperative to explore the evolutionary basis of characteristic attributes that define chemotype and provide essential resources for a molecular breeding strategy enhanced production medicinal metabolites. Here, using single-molecule high-fidelity (HiFi) sequencing reads, we report chromosome-scale Chinese licorice (Glycyrrhiza uralensis), widely used herbal natural medicine. The entire was achieved in eight chromosomes, with contig scaffold N50 as 36.02 60.2...
Cornus officinalis, an important traditional medicinal plant, is used as major constituents of tonics, analgesics, and diuretics. While several studies have focused on its characteristic bioactive compounds, little known their biosynthesis. In this study, we performed LC-QTOF-MS-based metabolome RNA-seq-based transcriptome profiling for seven tissues C. officinalis. Untargeted analysis assigned chemical identities to 1,215 metabolites showed tissue-specific accumulation specialized with...
ATP-binding cassette (ABC) proteins play important roles in cells as importers and exporters but membrane they are subject to well-known challenges of isolating pure stable samples for study. One solution this problem is use styrene-maleic acid lipid particles (SMALPs). Styrene-maleic (SMA) can be added directly membranes, forming nanoparticles incorporating lipids. Here we Sav1866, a well-characterised bacterial protein, proxy ABC general. We show that monodispersed Sav1866 purified at high...
High-throughput RNA sequencing (RNA-seq) analysis of samples from Mallotus japonicus, a traditional medicinal plant, yielded two novel viruses tentatively named japonicus virus A (MjVA) and B (MjVB). The MjVA MjVB genomes encode proteins showing amino acid sequence similarities to those poleroviruses (the genus Polerovirus, the family Solemoviridae) amalgaviruses Amalgavirus, Amalgaviridae), respectively. genome contains seven highly overlapping open reading frames, which are translated...
ZnFe2O4 nano-catalyzed facile synthesis of tetrahydropyranoquinoline derivatives (4a–f) via one-pot multi-component Povarov's inverse-electron-demand hetero Diels–Alder reaction substituted aromatic aldehyde (1), amine (2) with dihydrofuran (3) under ultrasonic irradiation. This may be helpful to society get more active pharmaceutical ingredients. In the present study, a series tetrahydroquinoline were synthesized and confirmed several spectral characterization techniques. Synthetic approach...
Escalating rates of urbanization and climate change have led to increased occurrence harmful algal blooms (HABs) in natural waters. HABs caused by Microcystis aeruginosa produce toxic secondary metabolites, such as microcystins (MCs). To understand resource partitioning strategies between cell growth MC production response environmental triggers, we tested the effect interactions light nitrogen on PCC 7806. Statistical models revealed that both affected transcriptome metabolome, however, was...
Mallotus japonicus is a valuable traditional medicinal plant in East Asia for applications as gastrointestinal drug. However, the molecular components involved biosynthesis of bioactive metabolites have not yet been explored, primarily due to lack omics resources. In this study, we established metabolome and transcriptome resources M. capture diverse metabolite constituents active transcripts its regulation. A combination untargeted profiling with data-dependent fragmentation annotation...
Removal of hexavalent chromium from synthetic wastewater was performed by employing vegetable-tanned buffing dust, a byproduct tanneries. Different analysis techniques such as SEM, BET, and FTIR were used to characterize the dust. The experiment on adsorption carried out in batch manner. Investigations conducted into various operating parameters, dose adsorbent, contact period, initial Cr (VI) concentration. At 1g/100 mL period 280 minutes, maximum capacity noted. Langmuir, Freundlich,...
The genus Potyvirus (the family Potyviridae ) is the largest group of plant-infecting viruses transmitted by aphids. Through high-throughput RNA sequencing analysis asymptomatic samples Aconitum carmichaelii , a significant medicinal herb in Asia, we identified genome sequences two viruses, tentatively named potyvirus 1 (AcoPV1) and 2 (AcoPV2). genomes AcoPV1 AcoPV2 encode polyproteins composed 3,069 3,054 amino acids, respectively. Sequence comparisons phylogenetic analyses established that...