A5035823838- Cystic Fibrosis Research Advances
- Inhalation and Respiratory Drug Delivery
- Pneumonia and Respiratory Infections
- Neonatal Respiratory Health Research
- Immunodeficiency and Autoimmune Disorders
- Respiratory Support and Mechanisms
- Asthma and respiratory diseases
- Tracheal and airway disorders
- Pediatric health and respiratory diseases
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Saffron Plant Research Studies
- Antibiotic Resistance in Bacteria
- Neurogenetic and Muscular Disorders Research
- Allergic Rhinitis and Sensitization
- Antifungal resistance and susceptibility
- Respiratory and Cough-Related Research
- Inflammatory Biomarkers in Disease Prognosis
- Sinusitis and nasal conditions
- Immune responses and vaccinations
- Nosocomial Infections in ICU
- Child Nutrition and Water Access
- Sepsis Diagnosis and Treatment
- Gut microbiota and health
- Congenital Anomalies and Fetal Surgery
Shahid Beheshti University of Medical Sciences
2012-2024
Children's Medical Center
2013-2022
Imam Hossein Hospital
2013
Tehran University of Medical Sciences
2013
Hôpital Arnaud de Villeneuve
2006
The prevalence of rhinitis is high and frequently observed in association with asthma. Although the persistence predisposing factors such as adults, this has not yet been confirmed children.The aim present work to show relationship between asthma control asthmatic authors carried out a cross-sectional study by collecting clinical, spirometric, fractional exhaled nitric oxide (FeNO) data children aged from 4 17 years.One hundred seventeen were included. Asthma was optimal 37.6%, suboptimal...
This study was performed to investigate frequency and antimicrobial susceptibility of pulmonary pathogens in cystic fibrosis (CF) patients. 129 pediatric patients with CF were enrolled this cross-sectional study. Microbiological cultures based on sputum or pharyngeal swabs. Antibiotic susceptibilities the isolated bacteria determined by disk diffusion method. The main infecting Pseudomonas aeruginosa (38.8%), Klebsiella pneumoniae (11.6%) Staphyloccus areus (9.3%), respectively. most active...
Abstract Background Early detection of pulmonary contamination in children with cystic fibrosis (CF) is essential since these are vulnerable to Pseudomonas aeruginosa ( P. ) colonization. In Iran, home nebulization antibiotics a widespread practice treatment for patients CF and, the best our knowledge, no bacteriological surveys have been conducted till date this regard. Method This observational, cross sectional study was on 61 at Mofid Children’s Hospital, Tehran, from September 2017 march...
Background:Pseudomonas aeruginosa is the most common microorganism found in sputum culture of Cystic fibrosis (CF) patients causing pulmonary destruction. Aminoglycosides have a low diffuse rate from lipid membranes, and respiratory system secretions. Regarding burden exacerbation caused by pseudomonas cystic long term limited number clinical trials focused on appropriate treatment strategies, present study evaluated concurrent inhaled intravenous aminoglycoside antibiotics for as safe...
Background: Cystic fibrosis (CF) is one of the most prevalent inherited diseases in children. Coronavirus can lead to more severe respiratory complications patients with comorbidities, such as CF. Additionally, coronavirus disease 2019 (COVID-19) pandemic has imposed a substantial burden on both national and international healthcare systems. could influence CF patients’ morbidities mortalities. Methods: A descriptive retrospective study was performed at Mofid Children's Hospital determine...
Abstract INTRODUCTION Cystic fibrosis (CF) patients frequently experience gut microbiota dysbiosis. Probiotic supplementation is a potential therapeutic approach to modify and improve CF management through the gut–lung axis. The aim of this study was investigate effect Lactobacillus reuteri on pulmonary function test, respiratory symptoms growth in patients. METHODS A randomized, placebo‐controlled clinical trial carried out 40 children with aged from 6 20 years. Participants were designated...
Abstract Introduction Interstitial lung disease (ILD) is a prevalent complication in patients with common variable immunodeficiency (CVID) and often related to other characteristics such as bronchiectasis autoimmunity. Because the term ILD encompasses variety of acute chronic pulmonary conditions, diagnosis usually based on imaging features. Histopathology less available. This study was conducted aim investigating CVID. Materials methods In this retrospective cross-sectional study, sixty...
Reinfection rate with SARS-CoV-2 and degree of protection by the induced antibody after first episode infection is not well known, so it makes a big dilemma for health care personnel (HCP) who work in front line combating SARS-CoV-2. In this study, we investigated frequency redetection among HCP initial onset children's hospital during one year. Out 131 seropositive HCP, 13.7% them were symptomatic PCR positive 74-360 days sampling. Analysis demographic data showed correlation between higher...
Background: In December 2019, a new coronavirus appeared in China, as cause of acute respiratory disease. Healthcare Workers (HCWs) children's hospitals are one the groups who at high rate exposure to COVID-19 patients. The detection antibodies is useful and helps diagnose late or recent SARS-CoV-2 infection. Most children may present with asymptomatic mild infection can be silent sources community hospitals. Objectives: This study was conducted determine (IgM IgG) against Mofid hospital...
Background: One of the main aspects treatment in patients with cystic fibrosis (CF) is effective clearing airway secretions. Inhaled hypertonic saline (HTS) and mannitol are among drugs used for this purpose. There two forms mannitol, including dry-powder soluble form. We study. Objectives: The aim study was to evaluate effect inhaled on pulmonary function CF as well its comparison 5% HTS. Methods: This clinical trial performed 30 children ≥ 5 years age who referred clinic Mofid Children's...
Background: Recently, a relationship has been demonstrated between red blood cell distribution width (RDW) and mortality risk in critically ill patients although the exact mechanism of this association is still vague. However, impact changes RDW on sepsis its outcome not widely studied. Therefore, we studied prognostic pediatric with sepsis. Methods: A total 304 who were admitted to intensive care unit selected participate study. The day admission 4 8 days after PICU documented their SIRS...
OBJECTIVE:This study was performed to investigate frequency and antimicrobial susceptibility of pulmonary pathogens in cystic fibrosis (CF) patients. METHODS: 129 pediatric patients with CF were enrolled this cross-sectional study. Microbiological cultures based on sputum or pharyngeal swabs. Antibiotic susceptibilities the isolated bacteria determined by disk diffusion method. RESULTS: The main infecting Pseudomonas aeruginosa (38.8%), Klebsiella pneumoniae (11.6%) Staphyloccus areus...
CF patients experience several episodes of pulmonary exacerbations and reduction in their lung function progressively. Lung is not the only diagnostic index by physicians to decide if require antibiotic therapy following exacerbations. Non-invasive fecal indicators are increasingly being used assess intestinal inflammation. Calprotectin most extensively utilized biomarker recent researches.In this longitudinal study, 30 (1-18 years) without current infectious gastroenteritis were recruited...
Background: Cystic fibrosis (CF) is a multisystem disease presenting different manifestations, including the involvement of respiratory and gastrointestinal tract. Patients may be at risk for micronutrient depletion, particularly during illness infection. However, relationship between depletion pulmonary not established well. Objectives: This study aimed to determine serum levels calcium, phosphorus, magnesium, zinc, copper, selenium, vitamin D with severity in patients CF. Methods:...
Introduction: Tracheal tumors are rare in the pediatric population. Primary within trachea often present with non-specific symptoms during initial stages, leading to a delayed diagnosis. Prompt diagnosis of tracheal tumor is crucial due risk life-threatening airway obstruction it poses. This article discusses case twelve-year-old girl who experienced 8years breathing difficulties without an adequate response treatment. Case Presentation: The patient was referred Mofid Children's Hospital...
Background: Proper sedation in ill children can enhance treatment outcomes, provide comfort, control pain, reduce delirium, and prevent self-extubation. This study aimed to compare the “Comfort Scale” with “State Behavioral (SBS) under mechanical ventilation ICU develop a protocol. Methods: assessed 50 children, ranging from one month 15 years of age, who were hospitalized Mofid Hospital for over four months. The convenience sampling method was used select participants, then divided into two...