A5012921704- Renal cell carcinoma treatment
- Renal Diseases and Glomerulopathies
- Bladder and Urothelial Cancer Treatments
- Heterotopic Ossification and Related Conditions
- Systemic Sclerosis and Related Diseases
- Abdominal Trauma and Injuries
- Systemic Lupus Erythematosus Research
- Gout, Hyperuricemia, Uric Acid
- Hepatocellular Carcinoma Treatment and Prognosis
- Multiple and Secondary Primary Cancers
- Liver Disease Diagnosis and Treatment
- Nanoparticle-Based Drug Delivery
- Head and Neck Anomalies
- Nanoplatforms for cancer theranostics
- vaccines and immunoinformatics approaches
- Thyroid Cancer Diagnosis and Treatment
- Inflammatory Biomarkers in Disease Prognosis
- Hepatitis B Virus Studies
- Neuroendocrine Tumor Research Advances
- Pancreatic and Hepatic Oncology Research
- Innovative Microfluidic and Catalytic Techniques Innovation
- Immunotherapy and Immune Responses
- Acute Kidney Injury Research
Guangdong Medical College
2021-2024
Chinese PLA General Hospital
2020-2024
Nankai University
2020
Ionic liquid (IL)-loaded or metal ions-enriched nanoparticles have been witnessed to assist microwave ablation (MWA) and heighten heat utilization for tumor treatment, which, however, inevitably brings about cell dys-homeostasis severely endangers normal cells tissues. In this report, a nonionic MWA sensitizer that encapsulates ethyl formate (EF) doxorubicin (DOX) in liposomes (EF-DOX-Lips) was constructed reinforce combined therapy against incomplete MWA-induced recurrence. EF EF-DOX-Lips...
Background Symptomatic aseptic necrosis (SAN) followed by nodule rupture is a kind of severe complications after thermal ablation for benign thyroid nodules (BTN). No studies are available to evaluate its pathologic process, clinical manifestations, risk factors and effectiveness therapies microwave (MWA).Methods From 2012 2019, 398 patients who received MWA BTN were retrospectively reviewed. Clinical data included baseline patient characteristics, imaging features (internal vascularity the...
Hyperuricemia is an independent risk factor for chronic kidney disease and contributes to renal fibrosis. This study aims investigate the effect of Src family kinase (SFK) inhibition on development hyperuricemic nephropathy (HN) mechanisms involved. In a rat model HN, feeding rats mixture adenine potassium oxonate increased phosphorylation, severe glomerular sclerosis, interstitial fibrosis, accompanied by dysfunction urine microalbumin excretion. Administration PP1, highly selective SFK...
e14513 Background: Local recurrence of Hepatocellular Carcinoma (HCC) following potentially curative resection or ablation is an inevitable risk. T cells recognizing neoantigens are present in most cancers including HCC and offer a specific highly immunogenic target for the personalized vaccination as adjuvant therapy. The purpose this study to evaluate safety cell immune response neoantigen-based mRNA loaded dendritic (DC) vaccine (LK101) combined with regular patients (NCT03674073)....
Purpose To compare acute kidney injury (AKI) incidence between nephron sparing surgery (NSS) and microwave ablation (MWA) for T1a RCC patients, reveal the effect of AKI on survival prognosis, construct nomogram use Law Total Probability probability (SP) prediction.Materials methods Patients were studied retrospectively after NSS (n = 1267) or MWA 210) from January 1, 2011 to June 30, 2017. Using one Propensity Score Matching (PSM), 158 pairs patients identified cohort study. incidence, risk...
Previous studies have failed to investigate the specific effects of advanced age on survival outcomes by considering Charlson Comorbidity Index (CCI) and permutation in patients with T1a renal cell carcinoma (T1a RCC) treated microwave ablation (MWA). Notably, RCC guidelines recommended radiofrequency (RFA) active surveillance (AS) are both treatment options for elderly RCC, but whether MWA is superior AS light higher heating efficiency larger zone compared RFA not clear. This study aimed...
Several studies have revealed that the prognostic nutritional index (PNI) was associated with survival in several cancers. However, value of PNI hepatocellular carcinoma (HCC) patients following ultrasound-guided percutaneous microwave ablation (US-PMWA) remains unknown, especially hepatitis B virus (HBV) infection. Therefore, present study aimed to evaluate potential these patients.The medical records 1,047 HCC HBV infection US-PMWA were retrospectively reviewed. The association between...