- Amyloidosis: Diagnosis, Treatment, Outcomes
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Radiopharmaceutical Chemistry and Applications
- Prostate Cancer Treatment and Research
- Cancer Diagnosis and Treatment
- IgG4-Related and Inflammatory Diseases
- Metastasis and carcinoma case studies
- Sarcoma Diagnosis and Treatment
- Simulation-Based Education in Healthcare
- Medical Imaging and Pathology Studies
- Cardiac Arrest and Resuscitation
- Muscle and Compartmental Disorders
- Diverticular Disease and Complications
- Sarcoidosis and Beryllium Toxicity Research
- Diet, Metabolism, and Disease
- Drug-Induced Adverse Reactions
- Salivary Gland Tumors Diagnosis and Treatment
- Biliary and Gastrointestinal Fistulas
- Boron Compounds in Chemistry
- Cervical Cancer and HPV Research
- Diet and metabolism studies
- Soft tissue tumor case studies
- Mast cells and histamine
- Genital Health and Disease
- Veterinary medicine and infectious diseases
VA Central California Health Care System
2020-2024
VA Pittsburgh Healthcare System
2013-2020
UPMC Hillman Cancer Center
2020
University of Pittsburgh
2013-2018
Memphis VA Medical Center
2009
University of Tennessee Health Science Center
2008
University of Rochester Medical Center
2005
The 2001 American Society for Colposcopy and Cervical Pathology Consensus Guidelines recommend that women who have Papanicolaou (Pap) smears diagnosed as atypical squamous cells (ASC), cannot exclude high-grade intraepithelial lesion (HSIL) (ASC-H) should be referred immediate colposcopic examination. objective of this pilot study was to evaluate whether reflex human papillomavirus (HPV)-DNA testing performed on ASC-H may obviate the need examination.All ThinPrep Pap were or metaplastic...
Adamantinoma is a rare low-grade malignant bone tumor of epithelial origin. Metastatic adamantinoma has been reported to be resistant chemotherapy. We report case metastatic the lung, 10 years after initial diagnosis tibial mass. The patient received radiation therapy lung with partial response. A surveillance PET scan revealed progression mass and biopsy confirmed progressive residual adamantinoma. He carboplatin etoposide for 7 months achieved Four later, showed disease progression....
We describe three confirmed cases of squamous cell carcinoma (SCC) the lung with metastasis to gastrointestinal (GI) tract, two having epidermal growth factor receptor (EGFR) exon 19 deletions in all available specimens. One these patients received EGFR tyrosine kinase directed therapy for a brief period some symptom relief. Consideration mutation testing SCC lung, particularly those GI tract metastasis, may identify this potentially drug-targetable entity.
We report a rare case of metastatic renal cell carcinoma (RCC) in patient who developed rhabdomyolysis while on sunitinib. He was admitted to the hospital due muscle weakness, fatigue, poor oral intake, and difficulty swallowing March 2017. found have pancytopenia, liver failure, kidney high uric acid, increased creatine phosphokinase more than 5000. quickly lactic acidosis acute respiratory failure. transferred ICU, but his condition declined rapidly. died 3 days later. In this article we...
A high-fat, moderate-protein, low-carbohydrate ketogenic diet has been reported in the literature as a treatment option for patients with cancer.A 69-year-old veteran was initially diagnosed stage III colorectal cancer and progressed to having liver, pancreatic, omental lymph node involvement despite completing adjuvant FOLFOX (fluorouracil, leucovorin calcium, oxaliplatin) after surgery. The patient treated FOLFIRI irinotecan hydrochloride) bevacizumab, followed by encorafenib cetuximab on...
Abstract Patients with monoclonal gammopathy of renal significance should be treated clone‐directed therapy against sources proteins in order to prevent progression more advanced gammopathies and failure.
Abstract: Atypical fibroxanthoma (AFX) is a neoplasm that most commonly occurs on sun-damaged skin of the head and neck in elderly patients usually exhibits indolent clinical behavior with complete excision. The granular cell variant AFX demonstrates overlapping histopathologic features dermal non-neural tumor (NNGCT), which typically arises extremities young to middle aged adults rare reports regional metastasis. A subset NNGCT harbors ALK rearrangements expresses by immunohistochemistry....
A 74-year-old man presented with a 5-day history of diffuse abdominal pain, constipation, nausea, and vomiting. Radiography the abdomen revealed dilated small intestine that was consistent intestinal obstruction. An exploratory laparotomy performed.
Radium-223 (Ra-223) radioisotope has been reported to increase median survival in bone metastatic prostate carcinoma. The addition of Ra-223 abiraterone was associated with an increased risk fractures. There no comprehensive data for using veterans who were exposed Agent Orange (AO+).We present a retrospective study castration-resistant cancer (CRPC) received standard doses and other sequential therapies at US Department Veterans Affairs Pittsburgh Healthcare System Pennsylvania from January...
A 61-year old man was admitted for a 2-day history of watery diarrhea and RLQ pain, day after he ate pork sandwich. He had AAA endovascular repair 2 months PTA. On exam afebrile, with tender RLQ. WBC count 11k, 70% N. CT showed colitis the cecum ascending colon, patent SMA intact endoprosthesis (Img1a). Stool culture, O/P, C.diff were negative. Diarrhea pain improved IVF discharged 3 days later. previously scheduled surveillance colonoscopy 18 admission, cecal IC valve healing ulcers...
An elderly 72-year-old man presented with anemia, thrombocytopenia, monocytosis, splenomegaly and lymphadenopathy. Bone marrow biopsy was consistent mast cell neoplasm positive CD117, CD25, CD34 myeloblasts polymerase chain reaction (PCR) revealed mutation of D816V. He developed bilateral femoral neck fractures confirmed that he has systemic mastocytosis (SM). received cladribine midostaurin stable disease for 21 months. His SM associated clonal hematological non-mast lineage (SM-AHNMD)...
We report a rare case of monoclonal gammopathy renal significance with immunotactoid glomerulopathy and severe nephrotic syndrome. The patient was diagnosed B-cell IgM κ clone her syndrome is responding well to bortezomib, dexamethasone, rituximab.