About
Contact & Profiles
A5043673168
Research Areas
- CRISPR and Genetic Engineering
- Virus-based gene therapy research
- Viral Infectious Diseases and Gene Expression in Insects
Pfizer (United States)
2021
Adeno-associated virus (AAV) vectors, which contain a DNA transgene packaged into protein capsid, have shown tremendous therapeutic potential in recent years. An inherent characteristic of the manufacturing process is production empty capsids that lack and are therefore unable to provide intended benefit. The effect on clinical outcomes not well understood, but there immunogenicity efficacy concerns, these considered product-related impurity. Therefore, should be controlled during monitored...
10.1016/j.omtm.2021.08.009
article
EN
cc-by-nc-nd
Molecular Therapy — Methods & Clinical Development
2021-09-01
Coming Soon ...