Owing to white meat production Labeo rohita have vast economic importance, but its population has been reduced drastically in River Chenab due pollution. Atomic absorption spectrophotometry showed a merciless toxicity level of Cd, Cu, Mn, Zn, Pb, Cr, Sn and Hg. Comet assay results indicated significant (p < .05) DNA fragmentation as 42.21 ± 2.06%, 31.26 2.41% 21.84 2.21% comet tail, tail moment 17.71 1.79, 10.30 1.78 7.81 1.56, olive 13.58 1.306, 8.10 1.04 5.88 0.06, respectively, from three...

ABSTRACT Organophosphates and carbamates are major agrochemicals that strongly affect different neuroenzymes the growth of various fish species. Here, we study effect sublethal concentrations profenofos carbofuran on activity acetylcholinesterase (AChE) butyrylcholinesterase (BuChE) associated health risk in fish. Labeo rohita fingerlings were exposed to three carbofuran. The minimum cholinesterase activities brain, gills, muscle, kidney, liver, blood after exposure (0.06 mg/L). AChE BuChE...

The present study was aimed to evaluate the effect of heavy metals on an important tissue two fish species Cyprinus carpio and Wallago attu, sampled from Indus river, Mianwali District, Pakistan. concentration selected Fe, Cr, Cu, in gills, muscles, kidney liver compared with International standard food fish. overall metal concentrations among different weight categories C. were order Fe > Cu Cr >. In W. attu accumulation these were, Pb gills muscle Cu; muscles Pb; Pb. An increasing trend...

Abstract Untreated sewage and industrial wastes from Faisalabad city are disposed to River Chenab through Chakbandi Main Drain (CMD). The present project is planned investigate the effects of this freshwater pollution on body fish Ictalurus punctatus. specimens species were collected upstream downstream entrance CMD into Chenab. Fish gills, liver, kidney muscles dorsolateral regions subjected histopathology. Farmed areas used as control. polluted experimental sites showed significant damage...

The present study aimed to determine the degree of changes in histological architecture liver, gills, kidneys, and muscles fish Oreochromis niloticus collected from different polluted river sites. Fish samples Faisalabad Hatchery upstream Chakbandi drain acted as a control. Necrosis, hemorrhage, epithelial hyperplasia were observed gills inhabiting downstream entrance. Liver tissues found be affected by vacuolated cytoplasm, bile duct proliferation, melanomacrophages, necrosis. In kidney...

This investigation is aimed to study an impact of habitat degradation on proximate composition and amino acid (AAs) profile Catla catla, Labeo rohita Cirrhinus mrigala collected from polluted, non-polluted area (upstream) a commercial fish farm. The was estimated by the analyzer. C. catla polluted environment had highest lipid, protein ash contents (12.04 ± 0.01, 13.45 0.01 0.93 0.03%, respectively). high content (14.73 14.12 0. 01%) recorded in procured wild River Chenab controlled Farmed...

This research work was carried out to determine the effects of water contamination on fatty acid (FA) profile periphyton, zoobenthos, two Chinese carps and a common carp (Hypophthalmichthys molitrix, Ctenopharygodon idella Cyprinus carpio), captured from highly polluted (HP), less (LP), non-polluted (NP) sites Indus river. We found that concentration heavy metals in river locations exceeded permissible limits suggested by World Health Organization (WHO) US Environmental Protection Agency...

Targeting the serine biosynthesis pathway enzymes has turned up as a novel strategy for anti-cancer therapeutics. 3- Phosphoglycerate dehydrogenase (PHGDH) is rate-limiting enzyme that catalyzes conversion of 3-Phosphoglyceric acid (3-PG) into 3-Phosphohydroxy pyruvate (3-PPyr) in first step synthesis and perform critical role cancer progression. PHGDH been reported to be overexpressed different types cancers emerged target During this study, virtual screening tools were used identification...

Liver injury is a prevalent pathological process that can give rise to conditions such as fatty liver, cirrhosis, fibrosis, and even cancer. It has been observed plants natural products possess significant protective effects against liver injury. Current study was performed investigate the efficacy of almonds shell carbon tetrachloride (CCl4) induced hepatotoxicity in rat model. As contain large variety phenolic flavonoid compounds, which are largely associated with antioxidant...

ABSTRACT: The present study investigated the presence and potent source of pesticides specific pesticide bearing effluent release points on River Ravi, between Shahdara Balloki Headworks. Pakistan has banned use organochlorine nitrogen containing pesticides, yet no attention been paid to continuous monitoring assessment these make sure that they are not being used in practice. Levels selected residues were assessed water collected from 18 sampling sites Ravi its tributaries using a gas...

A study was carried out on the optimal dose of inorganic fertilizer used in carp polyculture system over a period 10 months. Three treatments were assigned: without fertilizer, with application 100 kg/ha/month and 150 as T1, T2 T3, respectively. Each treatment had three replications. The selected indigenous species Rui (Labeo rohita), Catla (Catla catla) Mrigal (Cirrhinus mrigala), exotic silver (Hypophthalamichthys molitrix), grass (Ctenopharyngodon idella), common (Cyprinus carpio) thai...

AbstractProfenofos and trizaophos (organophosphates) carbofuran carbaryl (carbamates) are among the major toxicants polluting freshwater bodies, as well exerting a significant effect on health of fish. In this study, 96 h LC50 most commonly used organophosphates carbamates was determined in one indigenous fish species, Labeo rohita fingerlings. Pesticides were applied to fingerlings that had been grown under optimized standard conditions maintained static bioassay system. Probit analysis for...

The levels of dichlorodiphenyltrichloroethane (DDT), dichlorodiphenyldichloroethylene (DDE), endosulfan, endosulfan sulfate, carbofuran, and cartap which were estimated in the flesh Catla catla sampled from ten sites Ravi River between its stretches Shahdara to Head Balloki studied know level contamination selected pesticides by GC-ECD method. All fish samples found contaminated with different concentrations DDT, DDE, carbofuran; however, DDT DDE more than maximum residue limits (MRLs) about...