G. de

ORCID: 0000-0002-0870-4219
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Research Areas
  • Sperm and Testicular Function
  • Reproductive Biology and Fertility
  • Neuropeptides and Animal Physiology
  • Receptor Mechanisms and Signaling
  • Reproductive Physiology in Livestock
  • Neuroendocrine regulation and behavior
  • Neurobiology and Insect Physiology Research
  • Ovarian function and disorders
  • Reproductive biology and impacts on aquatic species
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Hormonal and reproductive studies
  • Urologic and reproductive health conditions
  • Regulation of Appetite and Obesity
  • Genetic and phenotypic traits in livestock
  • Animal Genetics and Reproduction
  • Cancer, Stress, Anesthesia, and Immune Response
  • Biochemical effects in animals
  • Biochemical Analysis and Sensing Techniques
  • Animal Diversity and Health Studies
  • Neurotransmitter Receptor Influence on Behavior
  • Urological Disorders and Treatments
  • Hypothalamic control of reproductive hormones
  • Pharmacological Effects of Natural Compounds
  • Renin-Angiotensin System Studies
  • Chemical Synthesis and Analysis

The University of Sydney
2016-2025

New South Wales Department of Primary Industries
2023

University of Wisconsin–Madison
2021

University of California, Berkeley
2021

University of Warwick
2021

Environmental Earth Sciences
2019

University of Veterinary Science
2013-2017

Universidad Politécnica de Madrid
2017

Institut National de la Recherche Agronomique
2014

UNSW Sydney
2013

1. In the intact conscious dog, caerulein causes emesis and evacuation of bowel. The mean effective dose by intravenous route is 0.4-0.5 mug/kg, subcutaneous 3-4 mug/kg.2. gall bladder in situ or as an isolated preparation highly sensitive to caerulein. A few ng/kg injected intravenously are sufficient stimulate less than 1 per min when infused intravenously. contracted concentrations low 0.03-2 ng/ml. Krebs solution. There no tachyphylaxis but, generally, a good dose-response relationship....

10.1111/j.1476-5381.1968.tb07052.x article EN British Journal of Pharmacology 1968-10-01

The female genital tract includes several anatomical regions whose luminal fluids successively interact with gametes and embryos are involved in the fertilisation development processes. from inner cervix, uterus oviduct were collected along oestrous cycle at oestrus (Day 0 of cycle) during luteal phase 10) adult cyclic ewes. proteomes assessed by GeLC-MS/MS quantified spectral counting. A set 940 proteins identified including 291 differentially present one or regions. global analysis fluid...

10.1074/mcp.m115.052332 article EN cc-by Molecular & Cellular Proteomics 2016-01-01

1. The changes in blood pressure response to parenteral administration of bombesin, the active tetradecapeptide skin European discoglossid frogs Bombina bombina and variegata have been investigated some experimental animals.2. In most species, polypeptide elicited hypertension which was usually gradual onset slow disappear. Blood increases rarely exceeded 40-50 mmHg. At beginning an experiment dose-response relationship could often be observed, but later tachyphylaxis developed. During...

10.1111/j.1476-5381.1968.tb00474.x article EN British Journal of Pharmacology and Chemotherapy 1968-05-01

Successful artificial breeding underpins rapid genetic and production gains in animal agriculture. In sheep, insemination with frozen semen is performed via intrauterine laparoscopy as frozen-thawed spermatozoa do not traverse the cervix sufficient numbers for high fertility transcervical anatomically impossible most ewes. Historically, laparoscopic has always been considered reasonably successful, but recent anecdotal reports of poor place it at risk warning adoption. Understanding male,...

10.1016/j.anireprosci.2024.107453 article EN cc-by-nc-nd Animal Reproduction Science 2024-03-14

1. The South American amphibian Phyllomedusa sauvagei contains in its skin large amounts of a polypeptide closely resembling caerulein pharmacological actions. This polypeptide, called phyllocaerulein, was obtained pure form, and upon acid hydrolysis, enzymic digestion end-group determination experiments it proved to be nonapeptide the following composition Pyr-Glu-Tyr(SO(3)H)-Thr-Gly-Trp-Met-Asp-Phe-NH(2)It may seen that phyllocaerulein have common C-terminal heptapeptide N-terminal...

10.1111/j.1476-5381.1969.tb09538.x article EN British Journal of Pharmacology 1969-09-01

Sperm proteomes have emerged for several species; however, the extent of species similarity is unknown. Sheep are an important agricultural which a comprehensive sperm proteome has not been produced. In addition, potential proteomic factors from seminal plasma that may contribute to improved fertility after cervical insemination yet be explored. Here we use liquid chromatography-tandem mass spectrometry investigate ejaculated ram spermatozoa, with quantitative comparison epididymal...

10.1021/acs.jproteome.6b00530 article EN Journal of Proteome Research 2016-09-16

Seminal plasma purportedly plays a critical role in reproduction, but epididymal spermatozoa are capable of fertilisation following deposition the uterus, calling into question biological requirement this substance. Through combination direct observation utero using probe-based Confocal Laser Endomicroscopy, vivo assessment sperm fertility and vitro analysis various functional parameters, study investigated seminal transit through cervix ewe. Following cervical os, previously exposed to...

10.1530/rep-14-0285 article EN Reproduction 2014-08-28

1. The South American amphibian Leptodactylus pentadactylus labyrinthicus and the African Xenopus laevis contain in their skin a polypeptide indistinguishable from caerulein prepared Australian Hyla caerulea.2. content of different batches skins varies 10 to 500-600 mug/g tissue. Drying causes either moderate decrease or slight increase content. Methanol extraction gives considerably higher yields than acetone extraction.3. Caerulein caerulein-like polypeptides also occur several other...

10.1111/j.1476-5381.1970.tb10351.x article EN British Journal of Pharmacology 1970-01-01

Abstract Quantitative proteomic studies are contributing greatly to the understanding of spermatozoon through provision detailed information on proteins spermatozoa acquire and shed in acquisition fertility. Extracellular vesicles (EVs) thought aid delivery male reproductive tract. The aim this study is isolate, identify quantify EV isolated from ram seminal plasma. Ram sperm plasma membrane also using nitrogen cavitation identified better understand interplay between extracellular...

10.1002/pmic.201900289 article EN PROTEOMICS 2020-05-08

POIRIER, P., S. MAWHINNEY, L. GRONDIN, A. TREMBLAY, T. BRODERICK, J. CLÉROUX, C. CATELLIER, G. TANCRÈDE, and NADEAU. Prior meal enhances the plasma glucose lowering effect of exercise in type 2 diabetes. Med. Sci. Sports Exerc., Vol. 33, No. 8, 2001, pp. 1259–1264. Purpose To compare changes insulin levels response to 1 h performed at 60% V̇O2peak either fasted state or after a standardized breakfast subjects with Methods Ten sedentary men diabetes treated oral agents not under strict...

10.1097/00005768-200108000-00003 article EN Medicine & Science in Sports & Exercise 2001-08-01
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