Kian Sani

ORCID: 0000-0002-0907-8643
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About
Contact & Profiles
Research Areas
  • COVID-19 epidemiological studies
  • SARS-CoV-2 detection and testing
  • Viral Infections and Outbreaks Research
  • COVID-19 Digital Contact Tracing
  • Data-Driven Disease Surveillance
  • SARS-CoV-2 and COVID-19 Research
  • Biomedical and Engineering Education
  • Insect and Pesticide Research
  • COVID-19 Impact on Reproduction
  • Migration, Health and Trauma
  • Simulation-Based Education in Healthcare
  • Disaster Management and Resilience
  • Global Maternal and Child Health
  • Genetic diversity and population structure
  • Vector-borne infectious diseases

Broad Institute
2020-2023

Center for Systems Biology
2020-2022

Harvard University
2019-2022

Universities are vulnerable to infectious disease outbreaks, making them ideal environments study transmission dynamics and evaluate mitigation surveillance measures. Here, we analyze multimodal COVID-19-associated data collected during the 2020-2021 academic year at Colorado Mesa University introduce a SARS-CoV-2 response framework.We analyzed epidemiological sociobehavioral (demographics, contact tracing, WiFi-based co-location data) alongside pathogen (wastewater diagnostic testing, viral...

10.1016/j.medj.2022.09.003 article EN cc-by Med 2022-09-19

Babesia microti is tick-borne disease that an emerging threat to public health due increasing prevalence and expanding geographic range. Detection constant surveillance of babesiosis imperative for predicting pathogen expansion. Leveraging our whole genome sequence (WGS) analyses B. microti, we developed a single nucleotide polymorphism (SNP)-based high resolution melt (HRM) tool. We HRM assay using available data identified 775 SNPs. From these candidate SNPs, 32-SNP barcode robust...

10.1371/journal.pntd.0007194 article EN cc-by PLoS neglected tropical diseases 2019-03-25

Abstract Amid COVID-19, many institutions deployed vast resources to test their members regularly for safe reopening. This self-focused approach, however, not only overlooks surrounding communities but also remains blind community transmission that could breach the institution. To relative merits of a more altruistic strategy, we built an epidemiological model assesses differential impact on case counts when instead allocate proportion tests members’ close contacts in larger community. We...

10.1038/s41598-021-02605-4 article EN cc-by Scientific Reports 2022-02-03

Abstract Universities are particularly vulnerable to infectious disease outbreaks and also ideal environments study transmission dynamics evaluate mitigation surveillance measures when occur. Here, we introduce a SARS-CoV-2 response framework based on high-resolution, multimodal data collected during the 2020-2021 academic year at Colorado Mesa University. We analyzed epidemiological sociobehavioral (demographics, contact tracing, wifi-based co-location data) alongside pathogen (wastewater,...

10.1101/2022.07.06.22277314 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2022-07-07

An app-based educational outbreak simulator, Operation Outbreak (OO), seeks to engage and educate participants better respond outbreaks. Here, we examine the utility of OO for understanding epidemiological dynamics. The app enables experience-based learning about outbreaks, spreading a virtual pathogen via Bluetooth among participating smartphones. Deployed at many colleges in other settings, collects anonymized spatiotemporal data, including time duration contacts simulation. We report...

10.1016/j.patter.2022.100572 article EN cc-by Patterns 2022-08-01

Abstract Amid COVID-19, many institutions deployed vast resources to test their members regularly for safe reopening. This self-focused approach, however, not only overlooks surrounding communities but also remains blind community transmission that could breach the institution. To relative merits of a more altruistic strategy, we built an epidemiological model assesses differential impact on case counts when instead allocate proportion tests members’ close contacts in larger community. We...

10.1101/2021.03.16.21253669 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2021-03-24

ABSTRACT Operation Outbreak (OO), an app-based, educational outbreak simulator, seeks to engage, educate, and empower citizens prevent better respond infectious disease outbreaks. We examine the utility of OO for further understanding mitigating spread communicable diseases. The smartphone app uses Bluetooth a virtual pathogen among nearby participants’ devices simulate outbreak, providing experiential learning opportunity. Deployed at many college campuses other settings, collects these...

10.1101/2022.02.04.22270198 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2022-02-06

We demonstrate the effectiveness of an app-based, educational outbreak simulator, Operation Outbreak (OO), for understanding and mitigating spread communicable diseases. The OO smartphone app uses Bluetooth to a virtual pathogen among nearby participating devices simulate outbreak, providing experiential learning opportunity. Deployed at many college campuses other settings, collects these anonymized spatio-temporal data, including time duration contacts participants simulation. Here, we...

10.2139/ssrn.4042283 article EN SSRN Electronic Journal 2022-01-01
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